WormFlux: mechanistic analysis of C. elegans metabolism

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Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	5adtststerone
Name .....................................................	:	5alpha-Dihydrotestosterone, etc.Dihydrotestosterone, 17beta-Hydroxyandrostan-3-one, Androstanolone, 17beta-Hydroxy-5alpha-androstan-3-one
Model ID .....................................................	:	C03917
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C03917
Formula .....................................................	:	C19H30O2
Charge .....................................................	:	0
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	5adtststerone
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Not yet represented in WormPaths maps.

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC02497Name: dihydrotestosterone:NADP+ delta4-oxidoreductase Type: Regular Location: Cytosol KEGG ID: R02497 click to see details on this item	1.3.1.22Name: 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) Other names: cholestenone 5alpha-reductase, testosterone Delta4-5alpha-reductase, steroid 5alpha-reductase, 3-oxosteroid Delta4-dehydrogenase, 5alpha-reductase, steroid 5alpha-hydrogenase, 3-oxosteroid 5alpha-reductase, testosterone Delta4-hydrogenase, 4-ene-3-oxosteroid 5alpha-reductase, reduced nicotinamide adenine dinucleotide phosphate:Delta4-3-ketosteroid 5alpha-oxidoreductase, 4-ene-5alpha-reductase, Delta4-3-ketosteroid 5alpha-oxidoreductase, cholest-4-en-3-one 5alpha-reductase, testosterone 5alpha-reductase, 3-oxo-5alpha-steroid 4-dehydrogenase click to see details on this item	[c] : tststeroneName: Testosterone Formula: C19H28O2 Charge: 0 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		5adtststeroneName: 5alpha-Dihydrotestosterone Formula: C19H30O2 Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item	B0024.13 \| F42F12.3	Miscellaneous
TCE0612Name: 5alpha-Dihydrotestosterone transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	5adtststeroneName: 5alpha-Dihydrotestosterone Formula: C19H30O2 Charge: 0 click to see details on this item[e]		5adtststeroneName: 5alpha-Dihydrotestosterone Formula: C19H30O2 Charge: 0 click to see details on this item[c]	Not determined	Transport
EX03917Name: 5alpha-Dihydrotestosterone exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	5adtststeroneName: 5alpha-Dihydrotestosterone Formula: C19H30O2 Charge: 0 click to see details on this item[e]			Not applicable	Exchange with the environment

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