WormFlux: mechanistic analysis of C. elegans metabolism

HOME DOWNLOAD CITATION HELP

(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	1.2.1.31
Name .....................................................	:	L-aminoadipate-semialdehyde dehydrogenase, etc.Aminoadipate semialdehyde dehydrogenase, 2-aminoadipate semialdehyde dehydrogenase, Alpha-aminoadipate-semialdehyde dehydrogenase, Alpha-aminoadipate reductase, 2-aminoadipic semialdehyde dehydrogenase, L-alpha-aminoadipate delta-semialdehyde oxidoreductase, L-alpha-aminoadipate delta-semialdehyde:NAD+ oxidoreductase, L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase, L-2-aminoadipate 6-semialdehyde:NAD(P)+ 6-oxidoreductase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K14085ALDH7A1; aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Genes .....................................................	:	alh-9
Localization .....................................................	:	Mitochondria
Other associations .....................................................	:	See reaction table below.

External links

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM03102Name: L-2-Aminoadipate-6-semialdehyde:NAD+ 6-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R03102 click to see details on this item	1.2.1.31Name: L-aminoadipate-semialdehyde dehydrogenase Other names: aminoadipate semialdehyde dehydrogenase, 2-aminoadipate semialdehyde dehydrogenase, alpha-aminoadipate-semialdehyde dehydrogenase, alpha-aminoadipate reductase, 2-aminoadipic semialdehyde dehydrogenase, L-alpha-aminoadipate delta-semialdehyde oxidoreductase, L-alpha-aminoadipate delta-semialdehyde:NAD+ oxidoreductase, L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase, L-2-aminoadipate 6-semialdehyde:NAD(P)+ 6-oxidoreductase click to see details on this item	[m] : L2aadp6saName: L-2-Aminoadipate 6-semialdehyde Formula: C6H11NO3 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		L2aadpName: L-2-Aminoadipate Formula: C6H10NO4 Charge: -1 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	alh-9	Lysine degradation
RM03103Name: L-2-Aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R03103 click to see details on this item	1.2.1.31Name: L-aminoadipate-semialdehyde dehydrogenase Other names: aminoadipate semialdehyde dehydrogenase, 2-aminoadipate semialdehyde dehydrogenase, alpha-aminoadipate-semialdehyde dehydrogenase, alpha-aminoadipate reductase, 2-aminoadipic semialdehyde dehydrogenase, L-alpha-aminoadipate delta-semialdehyde oxidoreductase, L-alpha-aminoadipate delta-semialdehyde:NAD+ oxidoreductase, L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase, L-2-aminoadipate 6-semialdehyde:NAD(P)+ 6-oxidoreductase click to see details on this item	[m] : L2aadp6saName: L-2-Aminoadipate 6-semialdehyde Formula: C6H11NO3 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item		L2aadpName: L-2-Aminoadipate Formula: C6H10NO4 Charge: -1 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item	alh-9	Lysine degradation

The information and tools provided in this website are to be used for academic purposes only.