Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	1.2.1.18
Name .....................................................	:	Malonate-semialdehyde dehydrogenase (acetylating), etc.Malonic semialdehyde oxidative decarboxylase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K00140mmsA iolA ALDH6A1; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
Genes .....................................................	:	alh-8
Localization .....................................................	:	Mitochondria
Other associations .....................................................	:	See reaction table below.

External links

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM00705Name: 3-Oxopropanoate:NAD+ oxidoreductase (decarboxylating, CoA-acetylating) Type: Regular Location: Mitochondria KEGG ID: R00705 click to see details on this item	1.2.1.18Name: malonate-semialdehyde dehydrogenase (acetylating) Other names: malonic semialdehyde oxidative decarboxylase click to see details on this item 1.2.1.27Name: methylmalonate-semialdehyde dehydrogenase (acylating) Other names: MSDH, MMSA dehydrogenase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + msaName: Malonate semialdehyde Formula: C3H3O3 Charge: -1 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	alh-8	Propionate degradation
RM00706Name: 3-Oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating) Type: Regular Location: Mitochondria KEGG ID: R00706 click to see details on this item	1.2.1.18Name: malonate-semialdehyde dehydrogenase (acetylating) Other names: malonic semialdehyde oxidative decarboxylase click to see details on this item	[m] : coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + msaName: Malonate semialdehyde Formula: C3H3O3 Charge: -1 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item		accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item	alh-8	Propionate degradation

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