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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 1.14.16.1
Name ..................................................... : Phenylalanine 4-monooxygenase, etc.Phenylalaninase, Phenylalanine 4-hydroxylase, Phenylalanine hydroxylase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K00500phhA PAH; phenylalanine-4-hydroxylase [EC:1.14.16.1]
Genes ..................................................... : pah-1
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC01795Name: L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)
Type: Regular
Location: Cytosol
KEGG ID: R01795

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1.14.16.1Name: phenylalanine 4-monooxygenase
Other names: phenylalaninase, phenylalanine 4-hydroxylase, phenylalanine hydroxylase

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[c] : o2Name: O2
Formula: O2
Charge: 0




click to see details on this item + phe-LName: L-Phenylalanine
Formula: C9H11NO2
Charge: 0




click to see details on this item + thbptName: Tetrahydrobiopterin
Formula: C9H15N5O3
Charge: 0




click to see details on this item
dhbptName: "6,7-Dihydrobiopterin"
Formula: C9H13N5O3
Charge: 0




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + tyr-LName: L-Tyrosine
Formula: C9H11NO3
Charge: 0




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pah-1
Folate biosynthesis
RC07211Name: L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating) (First step)
Type: Regular
Location: Cytosol
KEGG ID: R07211

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1.14.16.1Name: phenylalanine 4-monooxygenase
Other names: phenylalaninase, phenylalanine 4-hydroxylase, phenylalanine hydroxylase

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[c] : o2Name: O2
Formula: O2
Charge: 0




click to see details on this item + phe-LName: L-Phenylalanine
Formula: C9H11NO2
Charge: 0




click to see details on this item + thbptName: Tetrahydrobiopterin
Formula: C9H15N5O3
Charge: 0




click to see details on this item
thbpt4acamName: Tetrahydrobiopterin-4a-carbinolamine
Formula: C9H15N5O4
Charge: 0




click to see details on this item + tyr-LName: L-Tyrosine
Formula: C9H11NO3
Charge: 0




click to see details on this item
pah-1
Folate biosynthesis
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