Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	1.14.11.2
Name .....................................................	:	Procollagen-proline dioxygenase, etc.Protocollagen hydroxylase, Proline hydroxylase, Proline,2-oxoglutarate 4-dioxygenase, Collagen proline hydroxylase, Hydroxylase, collagen proline, Peptidyl proline hydroxylase, Proline protocollagen hydroxylase, Proline, 2-oxoglutarate dioxygenase, Prolyl hydroxylase, Prolylprotocollagen dioxygenase, Prolylprotocollagen hydroxylase, Protocollagen proline 4-hydroxylase, Protocollagen proline dioxygenase, Protocollagen proline hydroxylase, Protocollagen prolyl hydroxylase, Prolyl 4-hydroxylase, Prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating, Procollagen-proline 4-dioxygenase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K00472E1.14.11.2; prolyl 4-hydroxylase [EC:1.14.11.2]
Genes .....................................................	:	C14E2.4, Y43F8B.19, dpy-18, phy-2, phy-3, phy-4
Localization .....................................................	:	Cytosol
Other associations .....................................................	:	See reaction table below.

External links

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC01252Name: L-Proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) Type: Regular Location: Cytosol KEGG ID: R01252 click to see details on this item	1.14.11.2Name: procollagen-proline dioxygenase Other names: protocollagen hydroxylase, proline hydroxylase, proline,2-oxoglutarate 4-dioxygenase, collagen proline hydroxylase, hydroxylase, collagen proline, peptidyl proline hydroxylase, proline protocollagen hydroxylase, proline, 2-oxoglutarate dioxygenase, prolyl hydroxylase, prolylprotocollagen dioxygenase, prolylprotocollagen hydroxylase, protocollagen proline 4-hydroxylase, protocollagen proline dioxygenase, protocollagen proline hydroxylase, protocollagen prolyl hydroxylase, prolyl 4-hydroxylase, prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating, procollagen-proline 4-dioxygenase click to see details on this item	[c] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item + pro-LName: L-Proline Formula: C5H9NO2 Charge: 0 click to see details on this item		4hpro-LTName: trans-4-Hydroxy-L-proline Formula: C5H9NO3 Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + succName: Succinate Formula: C4H4O4 Charge: -2 click to see details on this item	C14E2.4 | Y43F8B.19 | dpy-18 | phy-2 | phy-3 | phy-4	Proline metabolism
RC03219Name: Procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) Type: Regular Location: Cytosol KEGG ID: R03219 click to see details on this item	1.14.11.2Name: procollagen-proline dioxygenase Other names: protocollagen hydroxylase, proline hydroxylase, proline,2-oxoglutarate 4-dioxygenase, collagen proline hydroxylase, hydroxylase, collagen proline, peptidyl proline hydroxylase, proline protocollagen hydroxylase, proline, 2-oxoglutarate dioxygenase, prolyl hydroxylase, prolylprotocollagen dioxygenase, prolylprotocollagen hydroxylase, protocollagen proline 4-hydroxylase, protocollagen proline dioxygenase, protocollagen proline hydroxylase, protocollagen prolyl hydroxylase, prolyl 4-hydroxylase, prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating, procollagen-proline 4-dioxygenase click to see details on this item	[c] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item + pcollgproName: Procollagen L-proline (to be modified) Formula: XH Charge: 0 click to see details on this item		pcollg4hproName: Procollagen trans-4-hydroxy-L-proline Formula: XOH Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + succName: Succinate Formula: C4H4O4 Charge: -2 click to see details on this item	C14E2.4 | Y43F8B.19 | dpy-18 | phy-2 | phy-3 | phy-4	Collagen biosynthesis

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