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PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	5aizc
Name .....................................................	:	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate, etc.1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate, 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxylate, 1-(5'-Phosphoribosyl)-5-amino-4-carboxyimidazole, 5'-Phosphoribosyl-5-amino-4-imidazolecarboxylate, 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole, 5'-Phosphoribosyl-4-carboxy-5-aminoimidazole
Model ID .....................................................	:	C04751
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C04751
Formula .....................................................	:	C9H11N3O9P
Charge .....................................................	:	-3
Localization .....................................................	:	Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	5aizc
Other associations .....................................................	:	See reaction table below.
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Purine metabolism (c)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC04209Name: 1-(5-phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase Type: Regular Location: Cytosol KEGG ID: R04209 click to see details on this item	4.1.1.21Name: phosphoribosylaminoimidazole carboxylase Other names: 5-phosphoribosyl-5-aminoimidazole carboxylase, 5-amino-1-ribosylimidazole 5-phosphate carboxylase, AIR carboxylase, 1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase, ADE2, class II PurE, 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase click to see details on this item	[c] : airName: 5-amino-1-(5-phospho-D-ribosyl)imidazole Formula: C8H12N3O7P Charge: -2 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item		5aizcName: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate Formula: C9H11N3O9P Charge: -3 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	pacs-1	Purine metabolism
RC04591Name: 1-(5-Phosphoribosyl)-5-amino-4-carboxyimidazole:L-aspartate ligase (ADP-forming) Type: Regular Location: Cytosol KEGG ID: R04591 click to see details on this item	6.3.2.6Name: phosphoribosylaminoimidazolesuccinocarboxamide synthase Other names: phosphoribosylaminoimidazole-succinocarboxamide synthetase, PurC, SAICAR synthetase, 4-(N-succinocarboxamide)-5-aminoimidazole synthetase, 4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase, SAICARs, phosphoribosylaminoimidazolesuccinocarboxamide synthetase, 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase click to see details on this item	[c] : 5aizcName: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate Formula: C9H11N3O9P Charge: -3 click to see details on this item + asp-LName: L-Aspartate Formula: C4H6NO4 Charge: -1 click to see details on this item + atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item		25aicsName: (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate Formula: C13H15N4O12P Charge: -4 click to see details on this item + adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	pacs-1	Purine metabolism

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