Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	6pthp
Name .....................................................	:	"6-Pyruvoyl-5,6,7,8-tetrahydropterin", etc.6-Pyruvoyltetrahydropterin, 6-(1,2-Dioxopropyl)-5,6,7,8-tetrahydropterin, 6-Pyruvoyl-5,6,7,8-tetrahydropterin
Model ID .....................................................	:	C03684
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C03684
Formula .....................................................	:	C9H11N5O3
Charge .....................................................	:	0
Localization .....................................................	:	Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	6pthp
Other associations .....................................................	:	See reaction table below.
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Folate biosynthesis (c)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC04286Name: 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate lyase Type: Regular Location: Cytosol KEGG ID: R04286 click to see details on this item	4.2.3.12Name: 6-pyruvoyltetrahydropterin synthase Other names: 2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase, 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming) click to see details on this item	[c] : ahdtName: "2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate" Formula: C9H12N5O13P3 Charge: -4 click to see details on this item		6pthpName: "6-Pyruvoyl-5,6,7,8-tetrahydropterin" Formula: C9H11N5O3 Charge: 0 click to see details on this item + pppiName: Inorganic triphosphate Formula: HO10P3 Charge: -4 click to see details on this item	ptps-1	Folate biosynthesis
RCC0157Name: sepiapterin reductase Type: Regular Location: Cytosol KEGG ID: R04285;R01813 click to see details on this item	1.1.1.153Name: sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) Other names: SR click to see details on this item	[c] : 6pthpName: "6-Pyruvoyl-5,6,7,8-tetrahydropterin" Formula: C9H11N5O3 Charge: 0 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + (2) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item		(2) nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + thbptName: Tetrahydrobiopterin Formula: C9H15N5O3 Charge: 0 click to see details on this item	Unknown	Folate biosynthesis

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