WormFlux: mechanistic analysis of C. elegans metabolism

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Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	lpro
Name .....................................................	:	Lipoylprotein, etc.H-Protein-lipoyllysine
Model ID .....................................................	:	C02051
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C02051
Formula .....................................................	:	S2X
Charge .....................................................	:	0
Localization .....................................................	:	Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	lpro
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Glycine and threonine metabolism (m)

iCEL1314

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ID

Enzyme

Reactants

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Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM03425Name: glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating) Type: Regular Location: Mitochondria KEGG ID: R03425 click to see details on this item	1.4.4.2Name: glycine dehydrogenase (aminomethyl-transferring) Other names: P-protein, glycine decarboxylase, glycine-cleavage complex, glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating), protein P1, glycine dehydrogenase (decarboxylating), glycine cleavage system P-protein, glycine-cleavage complex P-protein click to see details on this item	[m] : glyName: Glycine Formula: C2H5NO2 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + lproName: Lipoylprotein Formula: S2X Charge: 0 click to see details on this item		alproName: S-Aminomethyldihydrolipoylprotein Formula: CH6NS2X Charge: 1 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	gldc-1 & (gcsh-1 \| gcsh-2)	Glycine and threonine metabolism
RM03815Name: dihydrolipoylprotein:NAD+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R03815 click to see details on this item	1.8.1.4Name: dihydrolipoyl dehydrogenase Other names: LDP-Glc, LDP-Val, dehydrolipoate dehydrogenase, diaphorase, dihydrolipoamide dehydrogenase, dihydrolipoamide:NAD+ oxidoreductase, dihydrolipoic dehydrogenase, dihydrothioctic dehydrogenase, lipoamide dehydrogenase (NADH), lipoamide oxidoreductase (NADH), lipoamide reductase, lipoamide reductase (NADH), lipoate dehydrogenase, lipoic acid dehydrogenase, lipoyl dehydrogenase, protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase click to see details on this item	[m] : dhlproName: Dihydrolipolprotein Formula: H2S2X Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		hName: H+ Formula: H Charge: 1 click to see details on this item + lproName: Lipoylprotein Formula: S2X Charge: 0 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	dld-1 & (gcsh-1 \| gcsh-2)	Glycine and threonine metabolism

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