WormFlux: mechanistic analysis of C. elegans metabolism

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? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	prostge2
Name .....................................................	:	Prostaglandin E2, etc.(5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate, (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate, Dinoprostone, PGE2
Model ID .....................................................	:	C00584
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00584
Formula .....................................................	:	C20H31O5
Charge .....................................................	:	-1
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	prostge2
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Not yet represented in WormPaths maps.

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC02265Name: (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13- dienoate E-isomerase Type: Regular Location: Cytosol KEGG ID: R02265 click to see details on this item	5.3.99.3Name: prostaglandin-E synthase Other names: prostaglandin-H2 E-isomerase, endoperoxide isomerase, endoperoxide isomerase, prostaglandin R-prostaglandin E isomerase, prostaglandin endoperoxide E isomerase, PGE isomerase, PGH-PGE isomerase, PGE2 isomerase, prostaglandin endoperoxide E2 isomerase, prostaglandin H-E isomerase click to see details on this item	[c] : prostgh2Name: Prostaglandin H2 Formula: C20H31O5 Charge: -1 click to see details on this item		prostge2Name: Prostaglandin E2 Formula: C20H31O5 Charge: -1 click to see details on this item	pges-2 \| ZC395.10	Arachidonic acid metabolism
DMN0066Name: Prostaglandin E2 demand Type: Demand Location: Cytosol KEGG ID: NA click to see details on this item	Not applicable	prostge2Name: Prostaglandin E2 Formula: C20H31O5 Charge: -1 click to see details on this item[c]			Not applicable	Demand reactions
TCE0474Name: Prostaglandin E2 transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	prostge2Name: Prostaglandin E2 Formula: C20H31O5 Charge: -1 click to see details on this item[e]		prostge2Name: Prostaglandin E2 Formula: C20H31O5 Charge: -1 click to see details on this item[c]	Not determined	Transport
EX00584Name: Prostaglandin E2 exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	prostge2Name: Prostaglandin E2 Formula: C20H31O5 Charge: -1 click to see details on this item[e]			Not applicable	Exchange with the environment

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