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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 2.1.2.1
Name ..................................................... : Glycine hydroxymethyltransferase, etc.Serine aldolase, Threonine aldolase, Serine hydroxymethylase, Serine hydroxymethyltransferase, Allothreonine aldolase, L-serine hydroxymethyltransferase, L-threonine aldolase, Serine hydroxymethyltransferase, Serine transhydroxymethylase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K00600glyA SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1]
Genes ..................................................... : mel-32
Localization ..................................................... : Cytosol, Mitochondria
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RM00945Name: 5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase
Type: Regular
Location: Mitochondria
KEGG ID: R00945

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2.1.2.1Name: glycine hydroxymethyltransferase
Other names: serine aldolase, threonine aldolase, serine hydroxymethylase, serine hydroxymethyltransferase, allothreonine aldolase, L-serine hydroxymethyltransferase, L-threonine aldolase, serine hydroxymethyltransferase, serine transhydroxymethylase

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[m] : ser-LName: L-Serine
Formula: C3H7NO3
Charge: 0




click to see details on this item + thfName: "5,6,7,8-Tetrahydrofolate"
Formula: C19H21N7O6
Charge: -2




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glyName: Glycine
Formula: C2H5NO2
Charge: 0




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + mlthfName: "5,10-Methylenetetrahydrofolate"
Formula: C20H21N7O6
Charge: -2




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mel-32
Folate cycle
RC00945Name: 5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase
Type: Regular
Location: Cytosol
KEGG ID: R00945

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2.1.2.1Name: glycine hydroxymethyltransferase
Other names: serine aldolase, threonine aldolase, serine hydroxymethylase, serine hydroxymethyltransferase, allothreonine aldolase, L-serine hydroxymethyltransferase, L-threonine aldolase, serine hydroxymethyltransferase, serine transhydroxymethylase

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[c] : ser-LName: L-Serine
Formula: C3H7NO3
Charge: 0




click to see details on this item + thfName: "5,6,7,8-Tetrahydrofolate"
Formula: C19H21N7O6
Charge: -2




click to see details on this item
glyName: Glycine
Formula: C2H5NO2
Charge: 0




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + mlthfName: "5,10-Methylenetetrahydrofolate"
Formula: C20H21N7O6
Charge: -2




click to see details on this item
mel-32
Folate cycle
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