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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 2.1.1.13
Name ..................................................... : Methionine synthase, etc.5-methyltetrahydrofolate---homocysteine S-methyltransferase, 5-methyltetrahydrofolate---homocysteine transmethylase, N-methyltetrahydrofolate:L-homocysteine methyltransferase, N5-methyltetrahydrofolate methyltransferase, N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase, N5-methyltetrahydrofolic---homocysteine vitamin B12 transmethylase, B12 N5-methyltetrahydrofolate homocysteine methyltransferase, Methyltetrahydrofolate---homocysteine vitamin B12 methyltransferase, Tetrahydrofolate methyltransferase, Tetrahydropteroylglutamate methyltransferase, Tetrahydropteroylglutamic methyltransferase, Vitamin B12 methyltransferase, Cobalamin-dependent methionine synthase, Methionine synthase (cobalamin-dependent), MetH
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K00548metH MTR; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Genes ..................................................... : metr-1
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC00946Name: methionine synthase
Type: Regular
Location: Cytosol
KEGG ID: R00946;R05182

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2.1.1.13Name: methionine synthase
Other names: 5-methyltetrahydrofolate---homocysteine S-methyltransferase, 5-methyltetrahydrofolate---homocysteine transmethylase, N-methyltetrahydrofolate:L-homocysteine methyltransferase, N5-methyltetrahydrofolate methyltransferase, N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase, N5-methyltetrahydrofolic---homocysteine vitamin B12 transmethylase, B12 N5-methyltetrahydrofolate homocysteine methyltransferase, methyltetrahydrofolate---homocysteine vitamin B12 methyltransferase, tetrahydrofolate methyltransferase, tetrahydropteroylglutamate methyltransferase, tetrahydropteroylglutamic methyltransferase, vitamin B12 methyltransferase, cobalamin-dependent methionine synthase, methionine synthase (cobalamin-dependent), MetH

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[c] : 5mthfName: 5-Methyltetrahydrofolate
Formula: C20H24N7O6
Charge: -1




click to see details on this item + hcys-LName: L-Homocysteine
Formula: C4H9NO2S
Charge: 0




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hName: H+
Formula: H
Charge: 1




click to see details on this item + met-LName: L-Methionine
Formula: C5H11NO2S
Charge: 0




click to see details on this item + thfName: "5,6,7,8-Tetrahydrofolate"
Formula: C19H21N7O6
Charge: -2




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metr-1 & mtrr-1
Folate cycle
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