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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 1.14.18.1
Name ..................................................... : Tyrosinase, etc.Monophenol monooxygenase, Phenolase, Monophenol oxidase, Cresolase, Monophenolase, Tyrosine-dopa oxidase, Monophenol monooxidase, Monophenol dihydroxyphenylalanine:oxygen oxidoreductase, N-acetyl-6-hydroxytryptophan oxidase, Monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase, O-diphenol:O2 oxidoreductase, Phenol oxidase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K00505TYR; tyrosinase [EC:1.14.18.1]
Genes ..................................................... : tyr-1, tyr-2, tyr-3, tyr-4, tyr-5, tyr-6
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC02383Name: Monophenol,L-dopa:oxygen oxidoreductase
Type: Regular
Location: Cytosol
KEGG ID: R02383

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1.14.18.1Name: tyrosinase
Other names: monophenol monooxygenase, phenolase, monophenol oxidase, cresolase, monophenolase, tyrosine-dopa oxidase, monophenol monooxidase, monophenol dihydroxyphenylalanine:oxygen oxidoreductase, N-acetyl-6-hydroxytryptophan oxidase, monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase, o-diphenol:O2 oxidoreductase, phenol oxidase

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[c] : tymName: Tyramine
Formula: C8H12NO
Charge: 1




click to see details on this item + o2Name: O2
Formula: O2
Charge: 0




click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced
Formula: C21H27N7O14P2
Charge: -2




click to see details on this item + hName: H+
Formula: H
Charge: 1




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dopaName: Dopamine
Formula: C8H12NO2
Charge: 1




click to see details on this item + nadName: Nicotinamide adenine dinucleotide
Formula: C21H26N7O14P2
Charge: -1




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




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tyr-1 | tyr-2 | tyr-3 | tyr-4 | tyr-5 | tyr-6
Miscellaneous
RC00731Name: L-Tyrosine:oxygen oxidoreductase
Type: Regular
Location: Cytosol
KEGG ID: R00731

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1.14.18.1Name: tyrosinase
Other names: monophenol monooxygenase, phenolase, monophenol oxidase, cresolase, monophenolase, tyrosine-dopa oxidase, monophenol monooxidase, monophenol dihydroxyphenylalanine:oxygen oxidoreductase, N-acetyl-6-hydroxytryptophan oxidase, monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase, o-diphenol:O2 oxidoreductase, phenol oxidase

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[c] : o2Name: O2
Formula: O2
Charge: 0




click to see details on this item + (2) tyr-LName: L-Tyrosine
Formula: C9H11NO3
Charge: 0




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(2) 34dhpheName: "3,4-Dihydroxy-L-phenylalanine"
Formula: C9H11NO4
Charge: 0




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tyr-1 | tyr-2 | tyr-3 | tyr-4 | tyr-5 | tyr-6
Tyrosine metabolism
RC02078Name: L-Tyrosine,L-dopa:oxygen oxidoreductase
Type: Regular
Location: Cytosol
KEGG ID: R02078

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1.14.18.1Name: tyrosinase
Other names: monophenol monooxygenase, phenolase, monophenol oxidase, cresolase, monophenolase, tyrosine-dopa oxidase, monophenol monooxidase, monophenol dihydroxyphenylalanine:oxygen oxidoreductase, N-acetyl-6-hydroxytryptophan oxidase, monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase, o-diphenol:O2 oxidoreductase, phenol oxidase

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[c] : (2) 34dhpheName: "3,4-Dihydroxy-L-phenylalanine"
Formula: C9H11NO4
Charge: 0




click to see details on this item + o2Name: O2
Formula: O2
Charge: 0




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(2) dopaqnName: Dopaquinone
Formula: C9H9NO4
Charge: 0




click to see details on this item + (2) h2oName: H2O
Formula: H2O
Charge: 0




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tyr-1 | tyr-2 | tyr-3 | tyr-4 | tyr-5 | tyr-6
Tyrosine metabolism
RCC0018Name: melanine biosynthesis (merged)
Type: Regular
Location: Cytosol
KEGG ID: R02962;R03672;R03674;R04884

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1.14.18.1Name: tyrosinase
Other names: monophenol monooxygenase, phenolase, monophenol oxidase, cresolase, monophenolase, tyrosine-dopa oxidase, monophenol monooxidase, monophenol dihydroxyphenylalanine:oxygen oxidoreductase, N-acetyl-6-hydroxytryptophan oxidase, monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase, o-diphenol:O2 oxidoreductase, phenol oxidase

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[c] : (2) dopaqnName: Dopaquinone
Formula: C9H9NO4
Charge: 0




click to see details on this item + (0.5) o2Name: O2
Formula: O2
Charge: 0




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34dhpheName: "3,4-Dihydroxy-L-phenylalanine"
Formula: C9H11NO4
Charge: 0




click to see details on this item + ind56qnName: Indole-5,6-quinone
Formula: C8H5NO2
Charge: 0




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + co2Name: CO2
Formula: CO2
Charge: 0




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tyr-1 | tyr-2 | tyr-3 | tyr-4 | tyr-5 | tyr-6
Tyrosine metabolism
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