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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 1.13.11.27
Name ..................................................... : 4-hydroxyphenylpyruvate dioxygenase, etc.P-hydroxyphenylpyruvic hydroxylase, P-hydroxyphenylpyruvate hydroxylase, P-hydroxyphenylpyruvate oxidase, P-hydroxyphenylpyruvic oxidase, P-hydroxyphenylpyruvate dioxygenase, P-hydroxyphenylpyruvic acid hydroxylase, 4-hydroxyphenylpyruvic acid dioxygenase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K00457HPD hppD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]
Genes ..................................................... : C31H2.4, hpd-1
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC01372Name: Phenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating)
Type: Regular
Location: Cytosol
KEGG ID: R01372

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1.13.11.27Name: 4-hydroxyphenylpyruvate dioxygenase
Other names: p-hydroxyphenylpyruvic hydroxylase, p-hydroxyphenylpyruvate hydroxylase, p-hydroxyphenylpyruvate oxidase, p-hydroxyphenylpyruvic oxidase, p-hydroxyphenylpyruvate dioxygenase, p-hydroxyphenylpyruvic acid hydroxylase, 4-hydroxyphenylpyruvic acid dioxygenase

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[c] : o2Name: O2
Formula: O2
Charge: 0




click to see details on this item + phpyrName: Phenylpyruvate
Formula: C9H7O3
Charge: -1




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2hyoxplacName: 2-Hydroxyphenylacetate
Formula: C8H7O3
Charge: -1




click to see details on this item + co2Name: CO2
Formula: CO2
Charge: 0




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C31H2.4 | hpd-1
Phenylalanine degradation
RC02521Name: 4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating)
Type: Regular
Location: Cytosol
KEGG ID: R02521

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1.13.11.27Name: 4-hydroxyphenylpyruvate dioxygenase
Other names: p-hydroxyphenylpyruvic hydroxylase, p-hydroxyphenylpyruvate hydroxylase, p-hydroxyphenylpyruvate oxidase, p-hydroxyphenylpyruvic oxidase, p-hydroxyphenylpyruvate dioxygenase, p-hydroxyphenylpyruvic acid hydroxylase, 4-hydroxyphenylpyruvic acid dioxygenase

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[c] : 34hppName: 3-(4-Hydroxyphenyl)pyruvate
Formula: C9H7O4
Charge: -1




click to see details on this item + o2Name: O2
Formula: O2
Charge: 0




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co2Name: CO2
Formula: CO2
Charge: 0




click to see details on this item + hgentisName: Homogentisate
Formula: C8H7O4
Charge: -1




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C31H2.4 | hpd-1
Tyrosine metabolism
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