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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 1.13.11.11
Name ..................................................... : Tryptophan 2,3-dioxygenase, etc.Tryptophan pyrrolase (ambiguous), Tryptophanase, Tryptophan oxygenase, Tryptamine 2,3-dioxygenase, Tryptophan peroxidase, Indoleamine 2,3-dioxygenase (ambiguous), Indolamine 2,3-dioxygenase (ambiguous), L-tryptophan pyrrolase, TDO, L-tryptophan 2,3-dioxygenase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K00453E1.13.11.11 TDO2; tryptophan 23-dioxygenase [EC:1.13.11.11]
Genes ..................................................... : tdo-2
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC00678Name: L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)
Type: Regular
Location: Cytosol
KEGG ID: R00678

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1.13.11.11Name: tryptophan 2,3-dioxygenase
Other names: tryptophan pyrrolase (ambiguous), tryptophanase, tryptophan oxygenase, tryptamine 2,3-dioxygenase, tryptophan peroxidase, indoleamine 2,3-dioxygenase (ambiguous), indolamine 2,3-dioxygenase (ambiguous), L-tryptophan pyrrolase, TDO, L-tryptophan 2,3-dioxygenase

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[c] : o2Name: O2
Formula: O2
Charge: 0




click to see details on this item + trp-LName: L-Tryptophan
Formula: C11H12N2O2
Charge: 0




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LfmkynrName: L-Formylkynurenine
Formula: C11H12N2O4
Charge: 0




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tdo-2
Tryptophan degradation
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