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Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 1.1.1.42
Name ..................................................... : Isocitrate dehydrogenase (NADP+), etc.Oxalosuccinate decarboxylase, Oxalsuccinic decarboxylase, Isocitrate (NADP) dehydrogenase, Isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase, NADP-specific isocitrate dehydrogenase, NADP-linked isocitrate dehydrogenase, NADP-dependent isocitrate dehydrogenase, NADP isocitric dehydrogenase, Isocitrate dehydrogenase (NADP-dependent), NADP-dependent isocitric dehydrogenase, Triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase, NADP+-linked isocitrate dehydrogenase, IDH (ambiguous), Dual-cofactor-specific isocitrate dehydrogenase, NADP+-ICDH, NADP+-IDH, IDP, IDP1, IDP2, IDP3
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K00031IDH1 IDH2 icd; isocitrate dehydrogenase [EC:1.1.1.42]
Genes ..................................................... : idh-1, idh-2
Localization ..................................................... : Cytosol, Mitochondria
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC00267Name: Isocitrate:NADP+ oxidoreductase
Type: Regular
Location: Cytosol
KEGG ID: R00267

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1.1.1.42Name: isocitrate dehydrogenase (NADP+)
Other names: oxalosuccinate decarboxylase, oxalsuccinic decarboxylase, isocitrate (NADP) dehydrogenase, isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase, NADP-specific isocitrate dehydrogenase, NADP-linked isocitrate dehydrogenase, NADP-dependent isocitrate dehydrogenase, NADP isocitric dehydrogenase, isocitrate dehydrogenase (NADP-dependent), NADP-dependent isocitric dehydrogenase, triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase, NADP+-linked isocitrate dehydrogenase, IDH (ambiguous), dual-cofactor-specific isocitrate dehydrogenase, NADP+-ICDH, NADP+-IDH, IDP, IDP1, IDP2, IDP3

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[c] : icitName: Isocitrate
Formula: C6H5O7
Charge: -3




click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




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akgName: 2-Oxoglutarate
Formula: C5H4O5
Charge: -2




click to see details on this item + co2Name: CO2
Formula: CO2
Charge: 0




click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




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idh-1
TCA cycle
RM00267Name: Isocitrate:NADP+ oxidoreductase
Type: Regular
Location: Mitochondria
KEGG ID: R00267

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1.1.1.42Name: isocitrate dehydrogenase (NADP+)
Other names: oxalosuccinate decarboxylase, oxalsuccinic decarboxylase, isocitrate (NADP) dehydrogenase, isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase, NADP-specific isocitrate dehydrogenase, NADP-linked isocitrate dehydrogenase, NADP-dependent isocitrate dehydrogenase, NADP isocitric dehydrogenase, isocitrate dehydrogenase (NADP-dependent), NADP-dependent isocitric dehydrogenase, triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase, NADP+-linked isocitrate dehydrogenase, IDH (ambiguous), dual-cofactor-specific isocitrate dehydrogenase, NADP+-ICDH, NADP+-IDH, IDP, IDP1, IDP2, IDP3

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[m] : icitName: Isocitrate
Formula: C6H5O7
Charge: -3




click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item
akgName: 2-Oxoglutarate
Formula: C5H4O5
Charge: -2




click to see details on this item + co2Name: CO2
Formula: CO2
Charge: 0




click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item
idh-1 | idh-2
TCA cycle
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