WormFlux: mechanistic analysis of C. elegans metabolism

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Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	ascr3coa
Name .....................................................	:	ascaryl (ascr3) coa
Model ID .....................................................	:	CC0168
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	Not available
Formula .....................................................	:	C36H56N7O21P3S
Charge .....................................................	:	-4
Localization .....................................................	:	Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	Not available
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Ascaroside biosynthesis (c)

iCEL1314

Comments

Charge is based on similar metabolites.

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RCC0206Name: ascr1 synthesis Type: Regular Location: Cytosol KEGG ID: NA click to see details on this item	Not applicable	[c] : ascr3coaName: ascaryl (ascr3) coa Formula: C36H56N7O21P3S Charge: -4 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item		ascr1coaName: ascaryl (ascr1) coa Formula: C34H54N7O21P3S Charge: -4 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	maoc-1 & dhs-28 & daf-22	Ascaroside biosynthesis
RCC0207Name: ascr3 synthesis Type: Regular Location: Cytosol KEGG ID: NA click to see details on this item	Not applicable	[c] : ascr10coaName: ascaryl (ascr10) coa Formula: C36H58N7O21P3S Charge: -4 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		ascr3coaName: ascaryl (ascr3) coa Formula: C36H56N7O21P3S Charge: -4 click to see details on this item + h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item	acox-1.1 \| acox-1.4	Ascaroside biosynthesis
RCC0230Name: ascr-coa (ascr3) hydrolysis Type: Regular Location: Cytosol KEGG ID: NA click to see details on this item	Not applicable	[c] : ascr3coaName: ascaryl (ascr3) coa Formula: C36H56N7O21P3S Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		ascr3Name: Ascaroside 3 Formula: C15H25O6 Charge: -1 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	Not determined	Ascaroside biosynthesis

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