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  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network
Metabolite Overview
Abbreviation ..................................................... : xoltri25
Name ..................................................... : "7-alpha,25-Dihydroxycholesterol", etc.Cholest-5-ene-3beta,7alpha,25-triol, 7alpha,25-Dihydroxycholesterol, 5-Cholesten-3beta,7alpha,25-triol, 3beta,7alpha,25-Trihydroxycholest-5-ene
Model ID ..................................................... : C15520
KEGG ID (?) Compounds in KEGG database that match this compound. ..................................................... : C15520
Formula ..................................................... : C27H46O3
Charge ..................................................... : 0
Localization ..................................................... : Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. ..................................................... : xoltri25
Other associations ..................................................... : See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here.

Letters after map name indicate the compartments the metabolite is placed in the map:

(c) Cytosol
(m) Mitochondria
(e) Extracellular space ..................................................... 		: Biosynthesis of bile acid-like molecules (c)
Comments
ERROR
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC07209Name: oxysterol 7alpha-hydroxylase (acting on 25-hydroxycholesterol)
Type: Regular
Location: Cytosol
KEGG ID: R07209

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1.14.13.100Name: 25/26-hydroxycholesterol 7alpha-hydroxylase
Other names: 25-hydroxycholesterol 7alpha-monooxygenase, CYP7B1, CYP7B1 oxysterol 7alpha-hydroxylase, 27-hydroxycholesterol 7-monooxygenase, 27-hydroxycholesterol 7alpha-hydroxylase, cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating), 25-hydroxycholesterol 7alpha-hydroxylase

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[c] : hName: H+
Formula: H
Charge: 1




click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item + o2Name: O2
Formula: O2
Charge: 0




click to see details on this item + xol25ohName: 25-Hydroxycholesterol
Formula: C27H46O2
Charge: 0




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h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item + xoltri25Name: "7-alpha,25-Dihydroxycholesterol"
Formula: C27H46O3
Charge: 0




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To be determined
Biosynthesis of bile acid-like molecules
RC08723Name: 3beta-hydroxy-Delta5-C27-steroid oxidoreductase
Type: Regular
Location: Cytosol
KEGG ID: R08723

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1.1.1.181Name: cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase
Other names: 3beta-hydroxy-Delta5-C27-steroid oxidoreductase

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[c] : xoltri25Name: "7-alpha,25-Dihydroxycholesterol"
Formula: C27H46O3
Charge: 0




click to see details on this item + nadName: Nicotinamide adenine dinucleotide
Formula: C21H26N7O14P2
Charge: -1




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xol25oneName: 7alpha,25-Dihydroxy-4-cholesten-3-one
Formula: C27H44O3
Charge: 0




click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced
Formula: C21H27N7O14P2
Charge: -2




click to see details on this item + hName: H+
Formula: H
Charge: 1




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hsd-1 | hsd-2 | hsd-3
Biosynthesis of bile acid-like molecules
TCE0615Name: "7-alpha,25-Dihydroxycholesterol" transport
Type: Transport
Location: Cytosol, Extracellular
KEGG ID: NA

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Not applicable
xoltri25Name: "7-alpha,25-Dihydroxycholesterol"
Formula: C27H46O3
Charge: 0




click to see details on this item[c]
xoltri25Name: "7-alpha,25-Dihydroxycholesterol"
Formula: C27H46O3
Charge: 0




click to see details on this item[e]
Not determined
Transport
EX15520Name: "7-alpha,25-Dihydroxycholesterol" exchange
Type: Exchange
Location: Extracellular
KEGG ID: NA

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Not applicable
xoltri25Name: "7-alpha,25-Dihydroxycholesterol"
Formula: C27H46O3
Charge: 0




click to see details on this item[e]
Not applicable
Exchange with the environment
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