WormFlux: mechanistic analysis of C. elegans metabolism

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? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	2aobut
Name .....................................................	:	L-2-Amino-3-oxobutanoate, etc.L-2-Amino-3-oxobutanoic acid, L-2-Amino-acetoacetate, (S)-2-Amino-3-oxobutanoic acid
Model ID .....................................................	:	C03508
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C03508
Formula .....................................................	:	C4H7NO3
Charge .....................................................	:	0
Localization .....................................................	:	Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	2aobut
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Glycine and threonine metabolism (m)

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM00371Name: Acetyl-CoA:glycine C-acetyltransferase Type: Regular Location: Mitochondria KEGG ID: R00371 click to see details on this item	2.3.1.29Name: glycine C-acetyltransferase Other names: 2-amino-3-ketobutyrate CoA ligase, 2-amino-3-ketobutyrate coenzyme A ligase, 2-amino-3-ketobutyrate-CoA ligase, glycine acetyltransferase, aminoacetone synthase, aminoacetone synthetase, KBL, AKB ligase click to see details on this item	[m] : accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + glyName: Glycine Formula: C2H5NO2 Charge: 0 click to see details on this item		2aobutName: L-2-Amino-3-oxobutanoate Formula: C4H7NO3 Charge: 0 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item	T25B9.1	Glycine and threonine metabolism
RM01465Name: L-Threonine:NAD+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R01465 click to see details on this item	1.1.1.103Name: L-threonine 3-dehydrogenase Other names: L-threonine dehydrogenase, threonine 3-dehydrogenase, threonine dehydrogenase, TDH click to see details on this item	[m] : nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + thr-LName: L-Threonine Formula: C4H9NO3 Charge: 0 click to see details on this item		2aobutName: L-2-Amino-3-oxobutanoate Formula: C4H7NO3 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	F08F3.4	Glycine and threonine metabolism
RM03758Name: L-2-Amino-3-oxobutanoic acid decarboxylation Type: Regular Location: Mitochondria KEGG ID: R03758 click to see details on this item	spontaneous	[m] : 2aobutName: L-2-Amino-3-oxobutanoate Formula: C4H7NO3 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		aactName: Aminoacetone Formula: C3H8NO Charge: 1 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	Not applicable	Glycine and threonine metabolism

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