WormFlux: mechanistic analysis of C. elegans metabolism

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Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	4mlacac
Name .....................................................	:	4-Maleylacetoacetate, etc.4-Maleylacetoacetic acid
Model ID .....................................................	:	C01036
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C01036
Formula .....................................................	:	C8H6O6
Charge .....................................................	:	-2
Localization .....................................................	:	Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	4mlacac
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Tyrosine metabolism (c)

iCEL1314

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Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC02519Name: Homogentisate:oxygen 1,2-oxidoreductase (decyclizing) Type: Regular Location: Cytosol KEGG ID: R02519 click to see details on this item	1.13.11.5Name: homogentisate 1,2-dioxygenase Other names: homogentisicase, homogentisate oxygenase, homogentisate dioxygenase, homogentisate oxidase, homogentisic acid oxidase, homogentisic acid oxygenase, homogentisic oxygenase click to see details on this item	[c] : hgentisName: Homogentisate Formula: C8H7O4 Charge: -1 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		4mlacacName: 4-Maleylacetoacetate Formula: C8H6O6 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	hgo-1	Tyrosine metabolism
RC03181Name: 4-Maleylacetoacetate cis-trans-isomerase Type: Regular Location: Cytosol KEGG ID: R03181 click to see details on this item	5.2.1.2Name: maleylacetoacetate isomerase Other names: maleylacetoacetic isomerase, maleylacetone isomerase, maleylacetone cis-trans-isomerase click to see details on this item	[c] : 4mlacacName: 4-Maleylacetoacetate Formula: C8H6O6 Charge: -2 click to see details on this item		4fumacacName: 4-Fumarylacetoacetate Formula: C8H6O6 Charge: -2 click to see details on this item	Y53G8B.1 \| gst-42 \| gst-43	Tyrosine metabolism

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