WormFlux: mechanistic analysis of C. elegans metabolism

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Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	o2s
Name .....................................................	:	Superoxide anion, etc.O2.-, O2-
Model ID .....................................................	:	C00704
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00704
Formula .....................................................	:	O2
Charge .....................................................	:	-1
Localization .....................................................	:	Mitochondria, Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	o2s
Other associations .....................................................	:	See reaction table below (6 reactions in total)

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Reactive oxygen species metabolism (c,e,m), Tryptophan degradation (c)

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC00275Name: superoxide:superoxide oxidoreductase Type: Regular Location: Cytosol KEGG ID: R00275 click to see details on this item	1.15.1.1Name: superoxide dismutase Other names: superoxidase dismutase, copper-zinc superoxide dismutase, Cu-Zn superoxide dismutase, ferrisuperoxide dismutase, superoxide dismutase I, superoxide dismutase II, SOD, Cu,Zn-SOD, Mn-SOD, Fe-SOD, SODF, SODS, SOD-1, SOD-2, SOD-3, SOD-4, hemocuprein, erythrocuprein, cytocuprein, cuprein , hepatocuprein click to see details on this item	[c] : (2) hName: H+ Formula: H Charge: 1 click to see details on this item + (2) o2sName: Superoxide anion Formula: O2 Charge: -1 click to see details on this item		h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item	sod-1 \| sod-4 \| sod-5	Reactive oxygen species metabolism
RM00275Name: superoxide:superoxide oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R00275 click to see details on this item	1.15.1.1Name: superoxide dismutase Other names: superoxidase dismutase, copper-zinc superoxide dismutase, Cu-Zn superoxide dismutase, ferrisuperoxide dismutase, superoxide dismutase I, superoxide dismutase II, SOD, Cu,Zn-SOD, Mn-SOD, Fe-SOD, SODF, SODS, SOD-1, SOD-2, SOD-3, SOD-4, hemocuprein, erythrocuprein, cytocuprein, cuprein , hepatocuprein click to see details on this item	[m] : (2) hName: H+ Formula: H Charge: 1 click to see details on this item + (2) o2sName: Superoxide anion Formula: O2 Charge: -1 click to see details on this item		h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item	sod-1 \| sod-2 \| sod-3	Reactive oxygen species metabolism
RC02670Name: Hydroxyanthranilate oxidation Type: Regular Location: Cytosol KEGG ID: R02670 click to see details on this item	1.11.1.6Name: catalase Other names: equilase, caperase, optidase, catalase-peroxidase, CAT click to see details on this item	[c] : (2) 3hanthrnName: 3-Hydroxyanthranilate Formula: C7H7NO3 Charge: 0 click to see details on this item + (4) o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		cinnavalininateName: Cinnavalininate Formula: C14H6N2O6 Charge: -2 click to see details on this item + (2) o2sName: Superoxide anion Formula: O2 Charge: -1 click to see details on this item + (2) h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item + (4) hName: H+ Formula: H Charge: 1 click to see details on this item	ctl-1 \| ctl-2 \| ctl-3	Tryptophan degradation
TCM0158Name: Superoxide anion transport Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	o2sName: Superoxide anion Formula: O2 Charge: -1 click to see details on this item[c]		o2sName: Superoxide anion Formula: O2 Charge: -1 click to see details on this item[m]	Not determined	Transport
TCE0627Name: Superoxide anion transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	o2sName: Superoxide anion Formula: O2 Charge: -1 click to see details on this item[c]		o2sName: Superoxide anion Formula: O2 Charge: -1 click to see details on this item[e]	Not determined	Transport
EX00704Name: Superoxide anion exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	o2sName: Superoxide anion Formula: O2 Charge: -1 click to see details on this item[e]			Not applicable	Exchange with the environment

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