Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	id3acald
Name .....................................................	:	Indole-3-acetaldehyde, etc.2-(Indol-3-yl)acetaldehyde, Indoleacetaldehyde
Model ID .....................................................	:	C00637
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00637
Formula .....................................................	:	C10H9NO
Charge .....................................................	:	0
Localization .....................................................	:	Mitochondria, Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	id3acald
Other associations .....................................................	:	See reaction table below.
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Tryptophan degradation (c,m)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM02678Name: Indole-3-acetaldehyde:NAD+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R02678 click to see details on this item	1.2.1.3Name: aldehyde dehydrogenase (NAD+) Other names: CoA-independent aldehyde dehydrogenase, m-methylbenzaldehyde dehydrogenase, NAD-aldehyde dehydrogenase, NAD-dependent 4-hydroxynonenal dehydrogenase, NAD-dependent aldehyde dehydrogenase, NAD-linked aldehyde dehydrogenase, propionaldehyde dehydrogenase, aldehyde dehydrogenase (NAD) click to see details on this item	[m] : id3acaldName: Indole-3-acetaldehyde Formula: C10H9NO Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		ind3acName: Indole-3-acetate Formula: C10H8NO2 Charge: -1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item	(alh-1 | alh-2 | alh-4) | alh-9	Tryptophan degradation
RC02678Name: Indole-3-acetaldehyde:NAD+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R02678 click to see details on this item	1.2.1.3Name: aldehyde dehydrogenase (NAD+) Other names: CoA-independent aldehyde dehydrogenase, m-methylbenzaldehyde dehydrogenase, NAD-aldehyde dehydrogenase, NAD-dependent 4-hydroxynonenal dehydrogenase, NAD-dependent aldehyde dehydrogenase, NAD-linked aldehyde dehydrogenase, propionaldehyde dehydrogenase, aldehyde dehydrogenase (NAD) click to see details on this item	[c] : id3acaldName: Indole-3-acetaldehyde Formula: C10H9NO Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		ind3acName: Indole-3-acetate Formula: C10H8NO2 Charge: -1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item	(alh-2 | alh-4) | (alh-11 | alh-12)	Tryptophan degradation
RC02173Name: Tryptamine:oxygen oxidoreductase (deaminating) Type: Regular Location: Cytosol KEGG ID: R02173 click to see details on this item	1.4.3.4Name: monoamine oxidase Other names: adrenalin oxidase, adrenaline oxidase, amine oxidase (ambiguous), amine oxidase (flavin-containing), amine:oxygen oxidoreductase (deaminating) (flavin-containing), epinephrine oxidase, MAO, MAO A, MAO B, MAO-A, MAO-B, monoamine oxidase A, monoamine oxidase B, monoamine:O2 oxidoreductase (deaminating), polyamine oxidase (ambiguous), serotonin deaminase, spermidine oxidase (ambiguous), spermine oxidase (ambiguous), tyraminase, tyramine oxidase click to see details on this item	[c] : tryptaName: Tryptamine Formula: C10H13N2 Charge: 1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		id3acaldName: Indole-3-acetaldehyde Formula: C10H9NO Charge: 0 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item + h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item	amx-2	Tryptophan degradation
TCM1063Name: Indole-3-acetaldehyde transport Type: Transport Location: Mitochondria, Cytosol KEGG ID: NA click to see details on this item	Not applicable	id3acaldName: Indole-3-acetaldehyde Formula: C10H9NO Charge: 0 click to see details on this item[c]		id3acaldName: Indole-3-acetaldehyde Formula: C10H9NO Charge: 0 click to see details on this item[m]	Not determined	Transport

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