Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	sucsal
Name .....................................................	:	Succinic semialdehyde, etc.Succinate semialdehyde, 4-Oxobutanoate
Model ID .....................................................	:	C00232
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00232
Formula .....................................................	:	C4H5O3
Charge .....................................................	:	-1
Localization .....................................................	:	Mitochondria, Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	sucsal
Other associations .....................................................	:	See reaction table below.
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Glutamate / glutamine metabolism (m)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM00713Name: Succinate-semialdehyde:NAD+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R00713 click to see details on this item	1.2.1.24Name: succinate-semialdehyde dehydrogenase (NAD+) Other names: succinate semialdehyde dehydrogenase (NAD+), succinic semialdehyde dehydrogenase (NAD+), succinyl semialdehyde dehydrogenase (NAD+), succinate semialdehyde:NAD+ oxidoreductase click to see details on this item	[m] : sucsalName: Succinic semialdehyde Formula: C4H5O3 Charge: -1 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		succName: Succinate Formula: C4H4O4 Charge: -2 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item	alh-7	Glutamate / glutamine metabolism
RM01648Name: 4-aminobutanoate:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R01648 click to see details on this item	2.6.1.19Name: 4-aminobutyrate---2-oxoglutarate transaminase Other names: beta-alanine-oxoglutarate transaminase, aminobutyrate aminotransferase (ambiguous), beta-alanine aminotransferase, beta-alanine-oxoglutarate aminotransferase, gamma-aminobutyrate aminotransaminase (ambiguous), gamma-aminobutyrate transaminase (ambiguous), gamma-aminobutyrate-alpha-ketoglutarate aminotransferase, gamma-aminobutyrate-alpha-ketoglutarate transaminase, gamma-aminobutyrate:alpha-oxoglutarate aminotransferase, gamma-aminobutyric acid aminotransferase (ambiguous), gamma-aminobutyric acid transaminase (ambiguous), gamma-aminobutyric acid-alpha-ketoglutarate transaminase, gamma-aminobutyric acid-alpha-ketoglutaric acid aminotransferase, gamma-aminobutyric acid-2-oxoglutarate transaminase, gamma-aminobutyric transaminase (ambiguous), 4-aminobutyrate aminotransferase (ambiguous), 4-aminobutyrate-2-ketoglutarate aminotransferase, 4-aminobutyrate-2-oxoglutarate aminotransferase, 4-aminobutyrate-2-oxoglutarate transaminase, 4-aminobutyric acid 2-ketoglutaric acid aminotransferase, 4-aminobutyric acid aminotransferase (ambiguous), aminobutyrate transaminase (ambiguous), GABA aminotransferase (ambiguous), GABA transaminase (ambiguous), GABA transferase, GABA-alpha-ketoglutarate aminotransferase, GABA-alpha-ketoglutarate transaminase, GABA-alpha-ketoglutaric acid transaminase, GABA-alpha-oxoglutarate aminotransferase, GABA-2-oxoglutarate aminotransferase, GABA-2-oxoglutarate transaminase, GABA-oxoglutarate aminotransferase, GABA-oxoglutarate transaminase, glutamate-succinic semialdehyde transaminase, GabT click to see details on this item	[m] : 4abutName: 4-Aminobutanoate Formula: C4H9NO2 Charge: 0 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item		glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + sucsalName: Succinic semialdehyde Formula: C4H5O3 Charge: -1 click to see details on this item	gta-1	Glutamate / glutamine metabolism
TCE5366Name: Succinic semialdehyde transport Type: Transport Location: Extracellular, Cytosol KEGG ID: NA click to see details on this item	Not applicable	sucsalName: Succinic semialdehyde Formula: C4H5O3 Charge: -1 click to see details on this item[c]		sucsalName: Succinic semialdehyde Formula: C4H5O3 Charge: -1 click to see details on this item[e]	Not determined	Transport
EX00232Name: Succinic semialdehyde exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	sucsalName: Succinic semialdehyde Formula: C4H5O3 Charge: -1 click to see details on this item[e]			Not applicable	Exchange with the environment

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