WormFlux: mechanistic analysis of C. elegans metabolism

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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Pathway Overview

Name .....................................................	:	Methionine / S-adenosylmethionine cycle
Related pathway (?) The pathway found in other databases to which this pathway is related. .....................................................	:	ERROR
Number of reactions .....................................................	:	3

In WormPaths (?) If the pathway is available as a WormPaths map you will find the name and link of map here. .....................................................	:	Methionine / S-adenosylmethionine cycle

External links

Reactions (?) Click to see these reactions in the related KEGG pathway (only enzymes that are represented in kegg are highlighted).

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC00192Name: S-Adenosyl-L-homocysteine hydrolase Type: Regular Location: Cytosol KEGG ID: R00192 click to see details on this item	3.3.1.1Name: adenosylhomocysteinase Other names: S-adenosylhomocysteine synthase, S-adenosylhomocysteine hydrolase (ambiguous), adenosylhomocysteine hydrolase, S-adenosylhomocysteinase, SAHase, AdoHcyase click to see details on this item	[c] : ahcysName: S-Adenosyl-L-homocysteine Formula: C14H20N6O5S Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		adnName: Adenosine Formula: C10H13N5O4 Charge: 0 click to see details on this item + hcys-LName: L-Homocysteine Formula: C4H9NO2S Charge: 0 click to see details on this item	ahcy-1	Methionine / S-adenosylmethionine cycle
RC00177Name: ATP:L-methionine S-adenosyltransferase Type: Regular Location: Cytosol KEGG ID: R00177 click to see details on this item	2.5.1.6Name: methionine adenosyltransferase Other names: adenosylmethionine synthetase, ATP-methionine adenosyltransferase, methionine S-adenosyltransferase, methionine-activating enzyme, S-adenosyl-L-methionine synthetase, S-adenosylmethionine synthase, S-adenosylmethionine synthetase, AdoMet synthetase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + met-LName: L-Methionine Formula: C5H11NO2S Charge: 0 click to see details on this item		ametName: S-Adenosyl-L-methionine Formula: C15H23N6O5S Charge: 1 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	sams-1 \| sams-3 \| sams-4 \| sams-5	Methionine / S-adenosylmethionine cycle
RC00650Name: S-Adenosyl-L-methionine:L-homocysteine S-methyltransferase Type: Regular Location: Cytosol KEGG ID: R00650 click to see details on this item	2.1.1.10Name: homocysteine S-methyltransferase Other names: S-adenosylmethionine homocysteine transmethylase, S-methylmethionine homocysteine transmethylase, adenosylmethionine transmethylase, methylmethionine:homocysteine methyltransferase, adenosylmethionine:homocysteine methyltransferase, homocysteine methylase, homocysteine methyltransferase, homocysteine transmethylase, L-homocysteine S-methyltransferase, S-adenosyl-L-methionine:L-homocysteine methyltransferase, S-adenosylmethionine-homocysteine transmethylase, S-adenosylmethionine:homocysteine methyltransferase click to see details on this item	[c] : ametName: S-Adenosyl-L-methionine Formula: C15H23N6O5S Charge: 1 click to see details on this item + hcys-LName: L-Homocysteine Formula: C4H9NO2S Charge: 0 click to see details on this item		ahcysName: S-Adenosyl-L-homocysteine Formula: C14H20N6O5S Charge: 0 click to see details on this item + met-LName: L-Methionine Formula: C5H11NO2S Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	T13G4.4	Methionine / S-adenosylmethionine cycle

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