WormFlux: online metabolic network model of C. elegans; genome-scale reconstruction of the worm metabolism and flux balance analysis.

Walhout Lab web page:
walhoutlab.umassmed.edu

Email for WormFlux:
lutfu.yilmaz@umassmed.edu

WormFlux News

September 28, 2023
WormFlux moved to the cloud!
All functionality of the website is preserved except for FBA. Please use the old link to use this tool in the old server for a limited time. We will let you know if and when FBA tool becomes active here.

Mar 21, 2023
WormClust and related work on the transcriptional regulation of C. elegans metabolism is published in Molecular Systems Biology!

Feb 27, 2023
Our new tool WormClust is now available! Use WormClust to obtain metabolic clusters or pathways that best match a query gene based on gene expression profiles. See more here.

April 8, 2021
Check out our new Pathway Enrichment Analysis tool (PEA)!

December 23, 2020
WormPaths is published in bioRxiv.

December 21, 2020
Our new metabolic pathway visualization tool for C. elegans, WormPaths , is ready to explore. It consists of 66 hand-drawn pathway maps!

October 6, 2020
Our study on tissue relevant metabolism in C. elegans is published online.

March 13, 2020
Metabolic network model in WormFlux is updated and named iCEL1314! The former model (iCEL1273) is still available here .

June 9, 2017
WormFlux will be introduced in the C. elegans Metabolomics and Metabolic Networks Workshop on June 23 at the Worm meeting.

May 25, 2016
iCEL1273 is published in Cell Systems. Click to reach.

May 24, 2016
The search engine of WormFlux is updated. Partial hits are shown and wild characters are allowed.

May 19, 2016
iCEL1273 appears online in Cell Systems.

May 19, 2016
The first official version of WormFlux web site is launched.

February 15, 2016
Beta version of WormFlux web site is launched for a test ride.

November 15, 2015
Our current model, iCEL1273, is developed and finalized with 1273 genes, 1985 reactions, 623 enzymes, and 887 unique compounds.

Metabolic Network Modeling of C. elegans

The FBA tool is not available in our current server. You can find this tool (temporarily) in our previous server.

The current metabolic network model is iCEL1314. You can:

Use the orange buttons to explore the network or modify the biomass parameters.
Use the Download button to obtain this model in different formats.
Use the WormClust tool to evaluate the association of any gene of interest with the metabolic network based on similarities in gene expression.
Use the PEA button to perform pathway enrichment analysis for a set of genes of interest.

Note: This website is optimized for Firefox, and mostly compatible with Chrome and IE. It has not been thoroughly checked with other browsers.

The information and tools provided in this website are to be used for academic purposes only.