Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Pathway Overview

Name .....................................................	:	Pyrimidine metabolism
Related pathway (?) The pathway found in other databases to which this pathway is related. .....................................................	:	ERROR
Number of reactions .....................................................	:	50
In WormPaths (?) If the pathway is available as a WormPaths map you will find the name and link of map here. .....................................................	:	Pyrimidine metabolism

External links

Reactions (?) Click to see these reactions in the related KEGG pathway (only enzymes that are represented in kegg are highlighted).

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC00575Name: hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) Type: Regular Location: Cytosol KEGG ID: R00575 click to see details on this item	6.3.5.5Name: carbamoyl-phosphate synthase (glutamine-hydrolysing) Other names: carbamoyl-phosphate synthetase (glutamine-hydrolysing), carbamyl phosphate synthetase (glutamine), carbamoylphosphate synthetase II, glutamine-dependent carbamyl phosphate synthetase, carbamoyl phosphate synthetase, CPS, carbon-dioxide:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) click to see details on this item	[c] : (2) atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + gln-LName: L-Glutamine Formula: C5H10N2O3 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + hco3Name: Bicarbonate Formula: CHO3 Charge: -1 click to see details on this item		(2) adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + cbpName: Carbamoyl phosphate Formula: CH2NO5P Charge: -2 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	pyr-1	Pyrimidine metabolism
RC01993Name: (S)-dihydroorotate amidohydrolase Type: Regular Location: Cytosol KEGG ID: R01993 click to see details on this item	3.5.2.3Name: dihydroorotase Other names: carbamoylaspartic dehydrase, dihydroorotate hydrolase click to see details on this item	[c] : dhor-SName: (S)-Dihydroorotate Formula: C5H5N2O4 Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		cbaspName: N-Carbamoyl-L-aspartate Formula: C5H6N2O5 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	pyr-1	Pyrimidine metabolism
RM01868Name: (S)-dihydroorotate:quinone oxidoreductase Type: Regular Location: Mitochondria, Cytosol KEGG ID: R01868 click to see details on this item	1.3.5.2Name: dihydroorotate dehydrogenase (quinone) Other names: dihydroorotate:ubiquinone oxidoreductase, (S)-dihydroorotate:(acceptor) oxidoreductase, (S)-dihydroorotate:acceptor oxidoreductase, DHOdehase (ambiguous), DHOD (ambiguous), DHODase (ambiguous), DHODH click to see details on this item	dhor-SName: (S)-Dihydroorotate Formula: C5H5N2O4 Charge: -1 click to see details on this item[c] + qName: Ubiquinone Formula: C14H18O4 Charge: 0 click to see details on this item[m]		orotName: Orotate Formula: C5H3N2O4 Charge: -1 click to see details on this item[c] + qh2Name: Ubiquinol Formula: C14H20O4 Charge: 0 click to see details on this item[m]	dhod-1	Pyrimidine metabolism
RC01870Name: Orotidine-5-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase Type: Regular Location: Cytosol KEGG ID: R01870 click to see details on this item	2.4.2.10Name: orotate phosphoribosyltransferase Other names: orotidylic acid phosphorylase, orotidine-5'-phosphate pyrophosphorylase, OPRTase, orotate phosphoribosyl pyrophosphate transferase, orotic acid phosphoribosyltransferase, orotidine 5'-monophosphate pyrophosphorylase, orotidine monophosphate pyrophosphorylase, orotidine phosphoribosyltransferase, orotidylate phosphoribosyltransferase, orotidylate pyrophosphorylase, orotidylic acid pyrophosphorylase, orotidylic phosphorylase, orotidylic pyrophosphorylase click to see details on this item	[c] : orot5pName: Orotidine 5'-phosphate Formula: C10H10N2O11P Charge: -3 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item		orotName: Orotate Formula: C5H3N2O4 Charge: -1 click to see details on this item + prppName: 5-Phospho-alpha-D-ribose 1-diphosphate Formula: C5H8O14P3 Charge: -5 click to see details on this item	R12E2.11 | umps-1	Pyrimidine metabolism
RC00965Name: orotidine-5-phosphate carboxy-lyase (UMP-forming) Type: Regular Location: Cytosol KEGG ID: R00965 click to see details on this item	4.1.1.23Name: orotidine-5'-phosphate decarboxylase Other names: orotidine-5'-monophosphate decarboxylase, orotodylate decarboxylase, orotidine phosphate decarboxylase, OMP decarboxylase, orotate monophosphate decarboxylase, orotidine monophosphate decarboxylase, orotidine phosphate decarboxylase, OMP-DC, orotate decarboxylase, orotidine 5'-phosphate decarboxylase, orotidylic decarboxylase, orotidylic acid decarboxylase, orotodylate decarboxylase, ODCase, orotic decarboxylase, orotidine-5'-phosphate carboxy-lyase click to see details on this item	[c] : hName: H+ Formula: H Charge: 1 click to see details on this item + orot5pName: Orotidine 5'-phosphate Formula: C10H10N2O11P Charge: -3 click to see details on this item		co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + umpName: UMP Formula: C9H11N2O9P Charge: -2 click to see details on this item	umps-1	Pyrimidine metabolism
RC00963Name: Uridine 5-monophosphate phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R00963 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + umpName: UMP Formula: C9H11N2O9P Charge: -2 click to see details on this item		piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item + uriName: Uridine Formula: C9H12N2O6 Charge: 0 click to see details on this item	F25B5.3 | Y10G11A.1 | Y71H10B.1	Pyrimidine metabolism
RC00964Name: ATP:uridine 5-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R00964 click to see details on this item	2.7.1.48Name: uridine kinase Other names: pyrimidine ribonucleoside kinase, uridine-cytidine kinase, uridine kinase (phosphorylating), uridine phosphokinase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + uriName: Uridine Formula: C9H12N2O6 Charge: 0 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + umpName: UMP Formula: C9H11N2O9P Charge: -2 click to see details on this item	B0001.4 | F19B6.1	Pyrimidine metabolism
RC01876Name: Uridine:phosphate alpha-D-ribosyltransferase Type: Regular Location: Cytosol KEGG ID: R01876 click to see details on this item	2.4.2.3Name: uridine phosphorylase Other names: pyrimidine phosphorylase, UrdPase, UPH, UPase click to see details on this item	[c] : piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item + uriName: Uridine Formula: C9H12N2O6 Charge: 0 click to see details on this item		r1pName: alpha-D-Ribose 1-phosphate Formula: C5H9O8P Charge: -2 click to see details on this item + uraName: Uracil Formula: C4H4N2O2 Charge: 0 click to see details on this item	upp-1	Pyrimidine metabolism
RC00978Name: 5,6-Dihydrouracil:NADP+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R00978 click to see details on this item	1.3.1.2Name: dihydropyrimidine dehydrogenase (NADP+) Other names: dihydrothymine dehydrogenase, dihydrouracil dehydrogenase (NADP+), 4,5-dihydrothymine: oxidoreductase, DPD, DHPDH, dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate), DHU dehydrogenase, hydropyrimidine dehydrogenase, dihydropyrimidine dehydrogenase (NADP) click to see details on this item	[c] : 56duraName: "5,6-dihydrouracil" Formula: C4H6N2O2 Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item		hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + uraName: Uracil Formula: C4H4N2O2 Charge: 0 click to see details on this item	dpyd-1	Pyrimidine metabolism
RC02269Name: 5,6-Dihydrouracil amidohydrolase Type: Regular Location: Cytosol KEGG ID: R02269 click to see details on this item	3.5.2.2Name: dihydropyrimidinase Other names: hydantoinase, hydropyrimidine hydrase, hydantoin peptidase, pyrimidine hydrase, D-hydantoinase click to see details on this item	[c] : 56duraName: "5,6-dihydrouracil" Formula: C4H6N2O2 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		calaName: N-Carbamoyl-beta-alanine Formula: C4H7N2O3 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	dhp-1 | dhp-2	Pyrimidine metabolism
RC00905Name: N-Carbamoyl-beta-alanine amidohydrolase Type: Regular Location: Cytosol KEGG ID: R00905 click to see details on this item	3.5.1.6Name: beta-ureidopropionase click to see details on this item	[c] : calaName: N-Carbamoyl-beta-alanine Formula: C4H7N2O3 Charge: -1 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		ala-BName: beta-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item	upb-1	Pyrimidine metabolism
RC01055Name: uracil hydro-lyase Type: Regular Location: Cytosol KEGG ID: R01055 click to see details on this item	3.2.-.-Name: uracil hydro-lyase click to see details on this item	[c] : r5pName: alpha-D-Ribose 5-phosphate Formula: C5H9O8P Charge: -2 click to see details on this item + uraName: Uracil Formula: C4H4N2O2 Charge: 0 click to see details on this item		h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + psd5pName: Pseudouridine 5'-phosphate Formula: C9H11N2O9P Charge: -2 click to see details on this item	T24C12.3	Pyrimidine metabolism
RC03315Name: ATP:pseudouridine 5'-phosphotransferase; pseudouridine kinase Type: Regular Location: Cytosol KEGG ID: R03315 click to see details on this item	2.7.1.83Name: pseudouridine kinase Other names: pseudouridine kinase (phosphorylating) click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + psduriName: Pseudouridine Formula: C9H12N2O6 Charge: 0 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + psd5pName: Pseudouridine 5'-phosphate Formula: C9H11N2O9P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	T24C12.3	Pyrimidine metabolism
RC00158Name: ATP:UMP phosphotransferase Type: Regular Location: Cytosol KEGG ID: R00158 click to see details on this item	2.7.4.14Name: UMP/CMP kinase Other names: cytidylate kinase, deoxycytidylate kinase, CTP:CMP phosphotransferase, dCMP kinase, deoxycytidine monophosphokinase, UMP-CMP kinase, ATP:UMP-CMP phosphotransferase, pyrimidine nucleoside monophosphate kinase, uridine monophosphate-cytidine monophosphate phosphotransferase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + umpName: UMP Formula: C9H11N2O9P Charge: -2 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + udpName: UDP Formula: C9H11N2O12P2 Charge: -3 click to see details on this item	C29F7.3 | F40F8.1	Pyrimidine metabolism
RC00155Name: UDP phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R00155 click to see details on this item	3.6.1.6Name: nucleoside diphosphate phosphatase Other names: nucleoside-diphosphatase, thiaminpyrophosphatase, UDPase, inosine diphosphatase, adenosine diphosphatase, IDPase, ADPase, adenosinepyrophosphatase, guanosine diphosphatase, guanosine 5'-diphosphatase, inosine 5'-diphosphatase, uridine diphosphatase, uridine 5'-diphosphatase, type B nucleoside diphosphatase, GDPase, CDPase, nucleoside 5'-diphosphatase, type L nucleoside diphosphatase, NDPase, nucleoside diphosphate phosphohydrolase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + udpName: UDP Formula: C9H11N2O12P2 Charge: -3 click to see details on this item		hName: H+ Formula: H Charge: 1 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item + umpName: UMP Formula: C9H11N2O9P Charge: -2 click to see details on this item	(ZK563.7 | apy-1) | mig-23 | uda-1	Pyrimidine metabolism
RC00156Name: ATP:UDP phosphotransferase Type: Regular Location: Cytosol KEGG ID: R00156 click to see details on this item	2.7.4.6Name: nucleoside-diphosphate kinase Other names: nucleoside 5'-diphosphate kinase, nucleoside diphosphate (UDP) kinase, nucleoside diphosphokinase, nucleotide phosphate kinase, UDP kinase, uridine diphosphate kinase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + udpName: UDP Formula: C9H11N2O12P2 Charge: -3 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + utpName: UTP Formula: C9H11N2O15P3 Charge: -4 click to see details on this item	R05G6.5 | Y48G8AL.15 | ndk-1	Pyrimidine metabolism
RC00662Name: Uridine triphosphate pyrophosphohydrolase Type: Regular Location: Cytosol KEGG ID: R00662 click to see details on this item	3.6.1.19Name: nucleoside-triphosphate diphosphatase Other names: nucleoside-triphosphate pyrophosphatase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + utpName: UTP Formula: C9H11N2O15P3 Charge: -4 click to see details on this item		hName: H+ Formula: H Charge: 1 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item + umpName: UMP Formula: C9H11N2O9P Charge: -2 click to see details on this item	hap-1	Pyrimidine metabolism
RC00571Name: UTP:ammonia ligase (ADP-forming) Type: Regular Location: Cytosol KEGG ID: R00571 click to see details on this item	6.3.4.2Name: CTP synthase (glutamine hydrolysing) Other names: UTP---ammonia ligase, cytidine triphosphate synthetase, uridine triphosphate aminase, cytidine 5'-triphosphate synthetase, CTPS (gene name), pyrG (gene name), CTP synthase, UTP:ammonia ligase (ADP-forming) click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item + utpName: UTP Formula: C9H11N2O15P3 Charge: -4 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + ctpName: CTP Formula: C9H12N3O14P3 Charge: -4 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	ctps-1	Pyrimidine metabolism
RC00573Name: UTP:L-glutamine amido-ligase (ADP-forming) Type: Regular Location: Cytosol KEGG ID: R00573 click to see details on this item	6.3.4.2Name: CTP synthase (glutamine hydrolysing) Other names: UTP---ammonia ligase, cytidine triphosphate synthetase, uridine triphosphate aminase, cytidine 5'-triphosphate synthetase, CTPS (gene name), pyrG (gene name), CTP synthase, UTP:ammonia ligase (ADP-forming) click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + gln-LName: L-Glutamine Formula: C5H10N2O3 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + utpName: UTP Formula: C9H11N2O15P3 Charge: -4 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + ctpName: CTP Formula: C9H12N3O14P3 Charge: -4 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	ctps-1	Pyrimidine metabolism
RC00570Name: ATP:CDP phosphotransferase Type: Regular Location: Cytosol KEGG ID: R00570 click to see details on this item	2.7.4.6Name: nucleoside-diphosphate kinase Other names: nucleoside 5'-diphosphate kinase, nucleoside diphosphate (UDP) kinase, nucleoside diphosphokinase, nucleotide phosphate kinase, UDP kinase, uridine diphosphate kinase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + cdpName: CDP Formula: C9H12N3O11P2 Charge: -3 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + ctpName: CTP Formula: C9H12N3O14P3 Charge: -4 click to see details on this item	R05G6.5 | Y48G8AL.15 | ndk-1	Pyrimidine metabolism
RC00512Name: ATP:CMP phosphotransferase Type: Regular Location: Cytosol KEGG ID: R00512 click to see details on this item	2.7.4.14Name: UMP/CMP kinase Other names: cytidylate kinase, deoxycytidylate kinase, CTP:CMP phosphotransferase, dCMP kinase, deoxycytidine monophosphokinase, UMP-CMP kinase, ATP:UMP-CMP phosphotransferase, pyrimidine nucleoside monophosphate kinase, uridine monophosphate-cytidine monophosphate phosphotransferase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + cmpName: CMP Formula: C9H12N3O8P Charge: -2 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + cdpName: CDP Formula: C9H12N3O11P2 Charge: -3 click to see details on this item	C29F7.3 | F40F8.1	Pyrimidine metabolism
RC00511Name: Cytidine-5-monophosphate phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R00511 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : cmpName: CMP Formula: C9H12N3O8P Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		cytdName: Cytidine Formula: C9H13N3O5 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	F25B5.3 | Y10G11A.1 | Y71H10B.1	Pyrimidine metabolism
RC00513Name: ATP:cytidine 5-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R00513 click to see details on this item	2.7.1.48Name: uridine kinase Other names: pyrimidine ribonucleoside kinase, uridine-cytidine kinase, uridine kinase (phosphorylating), uridine phosphokinase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + cytdName: Cytidine Formula: C9H13N3O5 Charge: 0 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + cmpName: CMP Formula: C9H12N3O8P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	B0001.4 | F19B6.1	Pyrimidine metabolism
RC01878Name: Cytidine aminohydrolase Type: Regular Location: Cytosol KEGG ID: R01878 click to see details on this item	3.5.4.5Name: cytidine deaminase Other names: cytosine nucleoside deaminase, (deoxy)cytidine deaminase, cdd (gene name), CDA (gene name) click to see details on this item	[c] : cytdName: Cytidine Formula: C9H13N3O5 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item + uriName: Uridine Formula: C9H12N2O6 Charge: 0 click to see details on this item	cdd-1 | cdd-2	Pyrimidine metabolism
RC02024Name: 2-Deoxycytidine diphosphate:oxidized-thioredoxin 2-oxidoreductase Type: Regular Location: Cytosol KEGG ID: R02024 click to see details on this item	1.17.4.1Name: ribonucleoside-diphosphate reductase Other names: ribonucleotide reductase, CDP reductase, ribonucleoside diphosphate reductase, UDP reductase, ADP reductase, nucleoside diphosphate reductase, ribonucleoside 5'-diphosphate reductase, ribonucleotide diphosphate reductase, 2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase, RR click to see details on this item	[c] : cdpName: CDP Formula: C9H12N3O11P2 Charge: -3 click to see details on this item + trdrdName: Reduced thioredoxin Formula: XH2 Charge: 0 click to see details on this item		dcdpName: dCDP Formula: C9H12N3O10P2 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + trdoxName: Oxidized thioredoxin Formula: X Charge: 0 click to see details on this item	rnr-1 & rnr-2 & (F19G12.2 | F58F9.1)	Pyrimidine metabolism
RC02326Name: ATP:dCDP phosphotransferase Type: Regular Location: Cytosol KEGG ID: R02326 click to see details on this item	2.7.4.6Name: nucleoside-diphosphate kinase Other names: nucleoside 5'-diphosphate kinase, nucleoside diphosphate (UDP) kinase, nucleoside diphosphokinase, nucleotide phosphate kinase, UDP kinase, uridine diphosphate kinase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + dcdpName: dCDP Formula: C9H12N3O10P2 Charge: -3 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + dctpName: dCTP Formula: C9H12N3O13P3 Charge: -4 click to see details on this item	R05G6.5 | Y48G8AL.15 | ndk-1	Pyrimidine metabolism
RC01665Name: ATP:dCMP phosphotransferase Type: Regular Location: Cytosol KEGG ID: R01665 click to see details on this item	2.7.4.14Name: UMP/CMP kinase Other names: cytidylate kinase, deoxycytidylate kinase, CTP:CMP phosphotransferase, dCMP kinase, deoxycytidine monophosphokinase, UMP-CMP kinase, ATP:UMP-CMP phosphotransferase, pyrimidine nucleoside monophosphate kinase, uridine monophosphate-cytidine monophosphate phosphotransferase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + dcmpName: dCMP Formula: C9H12N3O7P Charge: -2 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + dcdpName: dCDP Formula: C9H12N3O10P2 Charge: -3 click to see details on this item	C29F7.3 | F40F8.1	Pyrimidine metabolism
RC01664Name: 2-Deoxycytidine 5-monophosphate phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R01664 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : dcmpName: dCMP Formula: C9H12N3O7P Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		dcytName: Deoxycytidine Formula: C9H13N3O4 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	F25B5.3 | Y10G11A.1 | Y71H10B.1	Pyrimidine metabolism
RC01663Name: dCMP aminohydrolase Type: Regular Location: Cytosol KEGG ID: R01663 click to see details on this item	3.5.4.12Name: dCMP deaminase Other names: deoxycytidylate deaminase, deoxy-CMP-deaminase, deoxycytidylate aminohydrolase, deoxycytidine monophosphate deaminase, deoxycytidine-5'-phosphate deaminase, deoxycytidine-5'-monophosphate aminohydrolase click to see details on this item	[c] : dcmpName: dCMP Formula: C9H12N3O7P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		dumpName: dUMP Formula: C9H11N2O8P Charge: -2 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item	ZK643.2	Pyrimidine metabolism
RC02099Name: ATP:deoxyuridine 5-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R02099 click to see details on this item	2.7.1.21Name: thymidine kinase Other names: thymidine kinase (phosphorylating), 2'-deoxythymidine kinase, deoxythymidine kinase (phosphorylating) click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + duriName: Deoxyuridine Formula: C9H12N2O5 Charge: 0 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + dumpName: dUMP Formula: C9H11N2O8P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	thk-1	Pyrimidine metabolism
RC02485Name: Deoxycytidine aminohydrolase Type: Regular Location: Cytosol KEGG ID: R02485 click to see details on this item	3.5.4.5Name: cytidine deaminase Other names: cytosine nucleoside deaminase, (deoxy)cytidine deaminase, cdd (gene name), CDA (gene name) click to see details on this item	[c] : dcytName: Deoxycytidine Formula: C9H13N3O4 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		duriName: Deoxyuridine Formula: C9H12N2O5 Charge: 0 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item	cdd-1 | cdd-2	Pyrimidine metabolism
RC02484Name: deoxyuridine:orthophosphate 2-deoxy-D-ribosyltransferase Type: Regular Location: Cytosol KEGG ID: R02484 click to see details on this item	2.4.2.1Name: purine-nucleoside phosphorylase Other names: inosine phosphorylase, PNPase, PUNPI, PUNPII, inosine-guanosine phosphorylase, nucleotide phosphatase, purine deoxynucleoside phosphorylase, purine deoxyribonucleoside phosphorylase, purine nucleoside phosphorylase, purine ribonucleoside phosphorylase click to see details on this item 2.4.2.3Name: uridine phosphorylase Other names: pyrimidine phosphorylase, UrdPase, UPH, UPase click to see details on this item	[c] : duriName: Deoxyuridine Formula: C9H12N2O5 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item		2dr1pName: 2-Deoxy-D-ribose 1-phosphate Formula: C5H9O7P Charge: -2 click to see details on this item + uraName: Uracil Formula: C4H4N2O2 Charge: 0 click to see details on this item	K02D7.1 | upp-1	Pyrimidine metabolism
RC02098Name: ATP:dUMP phosphotransferase Type: Regular Location: Cytosol KEGG ID: R02098 click to see details on this item	2.7.4.9Name: dTMP kinase Other names: thymidine monophosphate kinase, thymidylate kinase, thymidylate monophosphate kinase, thymidylic acid kinase, thymidylic kinase, deoxythymidine 5'-monophosphate kinase, TMPK, thymidine 5'-monophosphate kinase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + dumpName: dUMP Formula: C9H11N2O8P Charge: -2 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + dudpName: dUDP Formula: C9H11N2O11P2 Charge: -3 click to see details on this item	dtmk-1	Pyrimidine metabolism
RC02331Name: ATP:dUDP phosphotransferase Type: Regular Location: Cytosol KEGG ID: R02331 click to see details on this item	2.7.4.6Name: nucleoside-diphosphate kinase Other names: nucleoside 5'-diphosphate kinase, nucleoside diphosphate (UDP) kinase, nucleoside diphosphokinase, nucleotide phosphate kinase, UDP kinase, uridine diphosphate kinase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + dudpName: dUDP Formula: C9H11N2O11P2 Charge: -3 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + dutpName: dUTP Formula: C9H11N2O14P3 Charge: -4 click to see details on this item	R05G6.5 | Y48G8AL.15 | ndk-1	Pyrimidine metabolism
RC02100Name: dUTP nucleotidohydrolase Type: Regular Location: Cytosol KEGG ID: R02100 click to see details on this item	3.6.1.19Name: nucleoside-triphosphate diphosphatase Other names: nucleoside-triphosphate pyrophosphatase click to see details on this item 3.6.1.23Name: dUTP diphosphatase Other names: deoxyuridine-triphosphatase, dUTPase, dUTP pyrophosphatase, desoxyuridine 5'-triphosphate nucleotidohydrolase, desoxyuridine 5'-triphosphatase click to see details on this item	[c] : dutpName: dUTP Formula: C9H11N2O14P3 Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		dumpName: dUMP Formula: C9H11N2O8P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	hap-1 | dut-1	Pyrimidine metabolism
RC02018Name: 2-Deoxyuridine 5-diphosphate:oxidized-thioredoxin 2-oxidoreductase Type: Regular Location: Cytosol KEGG ID: R02018 click to see details on this item	1.17.4.1Name: ribonucleoside-diphosphate reductase Other names: ribonucleotide reductase, CDP reductase, ribonucleoside diphosphate reductase, UDP reductase, ADP reductase, nucleoside diphosphate reductase, ribonucleoside 5'-diphosphate reductase, ribonucleotide diphosphate reductase, 2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase, RR click to see details on this item	[c] : trdrdName: Reduced thioredoxin Formula: XH2 Charge: 0 click to see details on this item + udpName: UDP Formula: C9H11N2O12P2 Charge: -3 click to see details on this item		dudpName: dUDP Formula: C9H11N2O11P2 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + trdoxName: Oxidized thioredoxin Formula: X Charge: 0 click to see details on this item	rnr-1 & rnr-2 & (F19G12.2 | F58F9.1)	Pyrimidine metabolism
RC02094Name: ATP:dTMP phosphotransferase Type: Regular Location: Cytosol KEGG ID: R02094 click to see details on this item	2.7.4.9Name: dTMP kinase Other names: thymidine monophosphate kinase, thymidylate kinase, thymidylate monophosphate kinase, thymidylic acid kinase, thymidylic kinase, deoxythymidine 5'-monophosphate kinase, TMPK, thymidine 5'-monophosphate kinase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + dtmpName: dTMP Formula: C10H13N2O8P Charge: -2 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + dtdpName: dTDP Formula: C10H13N2O11P2 Charge: -3 click to see details on this item	dtmk-1	Pyrimidine metabolism
RC02093Name: ATP:dTDP phosphotransferase Type: Regular Location: Cytosol KEGG ID: R02093 click to see details on this item	2.7.4.6Name: nucleoside-diphosphate kinase Other names: nucleoside 5'-diphosphate kinase, nucleoside diphosphate (UDP) kinase, nucleoside diphosphokinase, nucleotide phosphate kinase, UDP kinase, uridine diphosphate kinase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + dtdpName: dTDP Formula: C10H13N2O11P2 Charge: -3 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item	R05G6.5 | Y48G8AL.15 | ndk-1	Pyrimidine metabolism
RC01569Name: Thymidylate 5-phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R01569 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : dtmpName: dTMP Formula: C10H13N2O8P Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item + thymdName: Thymidine Formula: C10H14N2O5 Charge: 0 click to see details on this item	F25B5.3 | Y10G11A.1 | Y71H10B.1	Pyrimidine metabolism
RC02102Name: 2-Deoxyuridine 5-monophosphate phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R02102 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : dumpName: dUMP Formula: C9H11N2O8P Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		duriName: Deoxyuridine Formula: C9H12N2O5 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	F25B5.3 | Y10G11A.1 | Y71H10B.1	Pyrimidine metabolism
RC01567Name: ATP:thymidine 5-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R01567 click to see details on this item	2.7.1.21Name: thymidine kinase Other names: thymidine kinase (phosphorylating), 2'-deoxythymidine kinase, deoxythymidine kinase (phosphorylating) click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + thymdName: Thymidine Formula: C10H14N2O5 Charge: 0 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + dtmpName: dTMP Formula: C10H13N2O8P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	thk-1	Pyrimidine metabolism
RC01415Name: 5,6-Dihydrothymine:NADP+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R01415 click to see details on this item	1.3.1.2Name: dihydropyrimidine dehydrogenase (NADP+) Other names: dihydrothymine dehydrogenase, dihydrouracil dehydrogenase (NADP+), 4,5-dihydrothymine: oxidoreductase, DPD, DHPDH, dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate), DHU dehydrogenase, hydropyrimidine dehydrogenase, dihydropyrimidine dehydrogenase (NADP) click to see details on this item	[c] : 56dthmName: "5,6-Dihydrothymine" Formula: C5H8N2O2 Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item		hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + thymName: Thymine Formula: C5H6N2O2 Charge: 0 click to see details on this item	dpyd-1	Pyrimidine metabolism
RC03055Name: 5,6-Dihydrothymine amidohydrolase Type: Regular Location: Cytosol KEGG ID: R03055 click to see details on this item	3.5.2.2Name: dihydropyrimidinase Other names: hydantoinase, hydropyrimidine hydrase, hydantoin peptidase, pyrimidine hydrase, D-hydantoinase click to see details on this item	[c] : 56dthmName: "5,6-Dihydrothymine" Formula: C5H8N2O2 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		3uibName: 3-Ureidoisobutyrate Formula: C5H9N2O3 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	dhp-1 | dhp-2	Pyrimidine metabolism
RC04666Name: 3-Ureidoisobutyrate amidohydrolase Type: Regular Location: Cytosol KEGG ID: R04666 click to see details on this item	3.5.1.6Name: beta-ureidopropionase click to see details on this item	[c] : 3uibName: 3-Ureidoisobutyrate Formula: C5H9N2O3 Charge: -1 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		3aib-DName: D-3-Amino-isobutanoate Formula: C4H9NO2 Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item	upb-1	Pyrimidine metabolism
RC07641Name: hydrogen-carbonate:ammonia amido-ligase (ADP-forming, carbamate-phosphorylating) Type: Regular Location: Cytosol KEGG ID: R07641 click to see details on this item	6.3.5.5Name: carbamoyl-phosphate synthase (glutamine-hydrolysing) Other names: carbamoyl-phosphate synthetase (glutamine-hydrolysing), carbamyl phosphate synthetase (glutamine), carbamoylphosphate synthetase II, glutamine-dependent carbamyl phosphate synthetase, carbamoyl phosphate synthetase, CPS, carbon-dioxide:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) click to see details on this item	[c] : (2) atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + hco3Name: Bicarbonate Formula: CHO3 Charge: -1 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item		(2) adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + cbpName: Carbamoyl phosphate Formula: CH2NO5P Charge: -2 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	pyr-1	Pyrimidine metabolism
RC00287Name: UDP-glucose glucophosphohydrolase Type: Regular Location: Cytosol KEGG ID: R00287 click to see details on this item	3.6.1.9Name: nucleotide diphosphatase Other names: nucleotide pyrophosphatase, nucleotide-sugar pyrophosphatase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + udpgName: UDPglucose Formula: C15H22N2O17P2 Charge: -2 click to see details on this item		g1pName: D-Glucose 1-phosphate Formula: C6H11O9P Charge: -2 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + umpName: UMP Formula: C9H11N2O9P Charge: -2 click to see details on this item	C27A7.1 | C27A7.3	Pyrimidine metabolism
RM00513Name: ATP:cytidine 5-phosphotransferase Type: Regular Location: Mitochondria KEGG ID: R00513 click to see details on this item	2.7.1.48Name: uridine kinase Other names: pyrimidine ribonucleoside kinase, uridine-cytidine kinase, uridine kinase (phosphorylating), uridine phosphokinase click to see details on this item	[m] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + cytdName: Cytidine Formula: C9H13N3O5 Charge: 0 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + cmpName: CMP Formula: C9H12N3O8P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	F19B6.1	Pyrimidine metabolism
RC00966Name: UMP:diphosphate phospho-alpha-D-ribosyltransferase Type: Regular Location: Cytosol KEGG ID: R00966 click to see details on this item	2.4.2.9Name: uracil phosphoribosyltransferase Other names: UMP pyrophosphorylase, UPRTase, UMP:pyrophosphate phosphoribosyltransferase, uridine 5'-phosphate pyrophosphorylase, uridine monophosphate pyrophosphorylase, uridylate pyrophosphorylase, uridylic pyrophosphorylase click to see details on this item	[c] : uraName: Uracil Formula: C4H4N2O2 Charge: 0 click to see details on this item + prppName: 5-Phospho-alpha-D-ribose 1-diphosphate Formula: C5H8O14P3 Charge: -5 click to see details on this item		umpName: UMP Formula: C9H11N2O9P Charge: -2 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	C47B2.2	Pyrimidine metabolism
RC03020Name: pseudouridine synthase Type: Regular Location: Cytosol KEGG ID: R03020 click to see details on this item	5.4.99.12Name: tRNA pseudouridine38-40 synthase Other names: TruA, tRNA pseudouridine synthase I, PSUI, hisT (gene name) click to see details on this item	[c] : uriName: Uridine Formula: C9H12N2O6 Charge: 0 click to see details on this item		psduriName: Pseudouridine Formula: C9H12N2O6 Charge: 0 click to see details on this item	Y73B6BL.29 | pus-1	Pyrimidine metabolism
RC01570Name: thymidine:phosphate deoxy-alpha-D-ribosyltransferase Type: Regular Location: Cytosol KEGG ID: R01570 click to see details on this item	2.4.2.4Name: thymidine phosphorylase Other names: pyrimidine phosphorylase, thymidine-orthophosphate deoxyribosyltransferase, animal growth regulators, blood platelet-derived endothelial cell growth factors, blood platelet-derived endothelial cell growth factor, deoxythymidine phosphorylase, gliostatins, pyrimidine deoxynucleoside phosphorylase, thymidine:phosphate deoxy-D-ribosyltransferase click to see details on this item	[c] : piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item + thymdName: Thymidine Formula: C10H14N2O5 Charge: 0 click to see details on this item		2dr1pName: 2-Deoxy-D-ribose 1-phosphate Formula: C5H9O7P Charge: -2 click to see details on this item + thymName: Thymine Formula: C5H6N2O2 Charge: 0 click to see details on this item	upp-1	Pyrimidine metabolism

The information and tools provided in this website are to be used for academic purposes only.