WormFlux: mechanistic analysis of C. elegans metabolism

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Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	3.1.3.5
Name .....................................................	:	5'-nucleotidase, etc.Uridine 5'-nucleotidase, 5'-adenylic phosphatase, Adenosine 5'-phosphatase, AMP phosphatase, Adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, Snake venom 5'-nucleotidase, Thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K01081E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
Genes .....................................................	:	F25B5.3, Y10G11A.1, Y71H10B.1
Localization .....................................................	:	Cytosol
Other associations .....................................................	:	See reaction table below (13 reactions in total)

External links

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC02323Name: Nicotinamide ribonucleotide phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R02323 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nmnName: NMN Formula: C11H14N2O8P Charge: -1 click to see details on this item		rnamName: N-Ribosylnicotinamide Formula: C11H15N2O5 Charge: 1 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	F25B5.3 \| Y10G11A.1 \| Y71H10B.1	Nicotinate and nicotinamide metabolism
RC03346Name: Nicotinate D-ribonucleotide phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R03346 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nicrntName: Nicotinate D-ribonucleotide Formula: C11H12NO9P Charge: -2 click to see details on this item		nicrnsName: Nicotinate D-ribonucleoside Formula: C11H13NO6 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	F25B5.3 \| Y10G11A.1 \| Y71H10B.1	Nicotinate and nicotinamide metabolism
RC01126Name: Inosine 5-monophosphate phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R01126 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + impName: IMP Formula: C10H11N4O8P Charge: -2 click to see details on this item		insName: Inosine Formula: C10H12N4O5 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	F25B5.3 \| Y10G11A.1 \| Y71H10B.1	Purine metabolism
RC00183Name: Adenosine 5-monophosphate phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R00183 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : ampName: AMP Formula: C10H12N5O7P Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		adnName: Adenosine Formula: C10H13N5O4 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	F25B5.3 \| Y10G11A.1 \| Y71H10B.1	Purine metabolism
RC02088Name: 2-Deoxyadenosine 5-monophosphate phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R02088 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : dampName: dAMP Formula: C10H12N5O6P Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		dad-2Name: Deoxyadenosine Formula: C10H13N5O3 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	F25B5.3 \| Y10G11A.1 \| Y71H10B.1	Purine metabolism
RC02719Name: Xanthosine 5-phosphate phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R02719 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + xmpName: Xanthosine 5'-phosphate Formula: C10H11N4O9P Charge: -2 click to see details on this item		piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item + xtsnName: Xanthosine Formula: C10H12N4O6 Charge: 0 click to see details on this item	F25B5.3 \| Y10G11A.1 \| Y71H10B.1	Purine metabolism
RC01227Name: Guanosine 5-monophosphate phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R01227 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : gmpName: GMP Formula: C10H12N5O8P Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		gsnName: Guanosine Formula: C10H13N5O5 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	F25B5.3 \| Y10G11A.1 \| Y71H10B.1	Purine metabolism
RC01968Name: 2-Deoxyguanosine 5-monophosphate phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R01968 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : dgmpName: dGMP Formula: C10H12N5O7P Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		dgsnName: Deoxyguanosine Formula: C10H13N5O4 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	F25B5.3 \| Y10G11A.1 \| Y71H10B.1	Purine metabolism
RC00963Name: Uridine 5-monophosphate phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R00963 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + umpName: UMP Formula: C9H11N2O9P Charge: -2 click to see details on this item		piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item + uriName: Uridine Formula: C9H12N2O6 Charge: 0 click to see details on this item	F25B5.3 \| Y10G11A.1 \| Y71H10B.1	Pyrimidine metabolism
RC00511Name: Cytidine-5-monophosphate phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R00511 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : cmpName: CMP Formula: C9H12N3O8P Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		cytdName: Cytidine Formula: C9H13N3O5 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	F25B5.3 \| Y10G11A.1 \| Y71H10B.1	Pyrimidine metabolism
RC01664Name: 2-Deoxycytidine 5-monophosphate phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R01664 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : dcmpName: dCMP Formula: C9H12N3O7P Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		dcytName: Deoxycytidine Formula: C9H13N3O4 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	F25B5.3 \| Y10G11A.1 \| Y71H10B.1	Pyrimidine metabolism
RC01569Name: Thymidylate 5-phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R01569 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : dtmpName: dTMP Formula: C10H13N2O8P Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item + thymdName: Thymidine Formula: C10H14N2O5 Charge: 0 click to see details on this item	F25B5.3 \| Y10G11A.1 \| Y71H10B.1	Pyrimidine metabolism
RC02102Name: 2-Deoxyuridine 5-monophosphate phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R02102 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : dumpName: dUMP Formula: C9H11N2O8P Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		duriName: Deoxyuridine Formula: C9H12N2O5 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	F25B5.3 \| Y10G11A.1 \| Y71H10B.1	Pyrimidine metabolism

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