Network Biomass

FBA FVA Integrate expression

Pathway Overview

Name .....................................................	:	Fatty acid elongation
Related pathway (?) The pathway found in other databases to which this pathway is related. .....................................................	:	ERROR
Number of reactions .....................................................	:	30

External links

Reactions (?) Click to see these reactions in the related KEGG pathway (only enzymes that are represented in kegg are highlighted).

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM04738Name: (S)-3-Hydroxyhexadecanoyl-CoA hydro-lyase Type: Regular Location: Mitochondria KEGG ID: R04738 click to see details on this item	4.2.1.17Name: enoyl-CoA hydratase Other names: enoyl hydrase, unsaturated acyl-CoA hydratase, beta-hydroxyacyl-CoA dehydrase, beta-hydroxyacid dehydrase, hydratase, enoyl coenzyme A, acyl coenzyme A hydrase, crotonase, crotonyl hydrase, 2-octenoyl coenzyme A hydrase, enoyl coenzyme A hydratase, 2-enoyl-CoA hydratase, short-chain enoyl-CoA hydratase, ECH, trans-2-enoyl-CoA hydratase, enoyl coenzyme A hydrase (D), enoyl coenzyme A hydrase (L), short chain enoyl coenzyme A hydratase, D-3-hydroxyacyl-CoA dehydratase, enol-CoA hydratase click to see details on this item	[m] : 3hhdcoaName: (S)-3-Hydroxyhexadecanoyl-CoA Formula: C37H62N7O18P3S Charge: -4 click to see details on this item		h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + hdd2coaName: trans-Hexadec-2-enoyl-CoA Formula: C37H60N7O17P3S Charge: -4 click to see details on this item	(ech-6 | ech-7) | (ech-1.2 | ech-1.1) | ech-3	Fatty acid elongation
RM04737Name: (S)-3-Hydroxyhexadecanoyl-CoA:NAD+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R04737 click to see details on this item	1.1.1.35Name: 3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl dehydrogenase, beta-keto-reductase, 3-keto reductase, 3-hydroxyacyl coenzyme A dehydrogenase, beta-hydroxyacyl-coenzyme A synthetase, beta-hydroxyacylcoenzyme A dehydrogenase, beta-hydroxybutyrylcoenzyme A dehydrogenase, 3-hydroxyacetyl-coenzyme A dehydrogenase, L-3-hydroxyacyl coenzyme A dehydrogenase, L-3-hydroxyacyl CoA dehydrogenase, beta-hydroxyacyl CoA dehydrogenase, 3beta-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxybutyryl-CoA dehydrogenase, beta-ketoacyl-CoA reductase, beta-hydroxy acid dehydrogenase, 3-L-hydroxyacyl-CoA dehydrogenase, 3-hydroxyisobutyryl-CoA dehydrogenase, 1-specific DPN-linked beta-hydroxybutyric dehydrogenase click to see details on this item 1.1.1.211Name: long-chain-3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl-CoA dehydrogenase, long-chain 3-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase, LCHAD click to see details on this item	[m] : 3ohdcoaName: 3-Oxohexadecanoyl-CoA Formula: C37H60N7O18P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item		3hhdcoaName: (S)-3-Hydroxyhexadecanoyl-CoA Formula: C37H62N7O18P3S Charge: -4 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	(B0272.3 | F54C8.1 | ech-8) | (ech-1.2 | ech-1.1)	Fatty acid elongation
RM03991Name: myristoyl-CoA:acetylCoA C-myristoyltransferase Type: Regular Location: Mitochondria KEGG ID: R03991 click to see details on this item	2.3.1.16Name: acetyl-CoA C-acyltransferase Other names: beta-ketothiolase, 3-ketoacyl-CoA thiolase, KAT, beta-ketoacyl coenzyme A thiolase, beta-ketoacyl-CoA thiolase, beta-ketoadipyl coenzyme A thiolase, beta-ketoadipyl-CoA thiolase, 3-ketoacyl CoA thiolase, 3-ketoacyl coenzyme A thiolase, 3-ketoacyl thiolase, 3-ketothiolase, 3-oxoacyl-CoA thiolase, 3-oxoacyl-coenzyme A thiolase, 6-oxoacyl-CoA thiolase, acetoacetyl-CoA beta-ketothiolase, acetyl-CoA acyltransferase, ketoacyl-CoA acyltransferase, ketoacyl-coenzyme A thiolase, long-chain 3-oxoacyl-CoA thiolase, oxoacyl-coenzyme A thiolase, pro-3-ketoacyl-CoA thiolase, thiolase I, 2-methylacetoacetyl-CoA thiolase [misleading] click to see details on this item	[m] : 3ohdcoaName: 3-Oxohexadecanoyl-CoA Formula: C37H60N7O18P3S Charge: -4 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item		accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + tdcoaName: Tetradecanoyl-CoA (n-C14:0CoA) Formula: C35H58N7O17P3S Charge: -4 click to see details on this item	B0303.3 | acaa-2	Fatty acid elongation
RM04740Name: (S)-3-Hydroxytetradecanoyl-CoA hydro-lyase Type: Regular Location: Mitochondria KEGG ID: R04740 click to see details on this item	4.2.1.17Name: enoyl-CoA hydratase Other names: enoyl hydrase, unsaturated acyl-CoA hydratase, beta-hydroxyacyl-CoA dehydrase, beta-hydroxyacid dehydrase, hydratase, enoyl coenzyme A, acyl coenzyme A hydrase, crotonase, crotonyl hydrase, 2-octenoyl coenzyme A hydrase, enoyl coenzyme A hydratase, 2-enoyl-CoA hydratase, short-chain enoyl-CoA hydratase, ECH, trans-2-enoyl-CoA hydratase, enoyl coenzyme A hydrase (D), enoyl coenzyme A hydrase (L), short chain enoyl coenzyme A hydratase, D-3-hydroxyacyl-CoA dehydratase, enol-CoA hydratase click to see details on this item	[m] : 3htdcoaName: (S)-3-Hydroxytetradecanoyl-CoA Formula: C35H58N7O18P3S Charge: -4 click to see details on this item		h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + td2coaName: trans-Tetradec-2-enoyl-CoA Formula: C35H56N7O17P3S Charge: -4 click to see details on this item	(ech-6 | ech-7) | (ech-1.2 | ech-1.1) | ech-3	Fatty acid elongation
RM04739Name: (S)-3-Hydroxytetradecanoyl-CoA:NAD+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R04739 click to see details on this item	1.1.1.211Name: long-chain-3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl-CoA dehydrogenase, long-chain 3-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase, LCHAD click to see details on this item 1.1.1.35Name: 3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl dehydrogenase, beta-keto-reductase, 3-keto reductase, 3-hydroxyacyl coenzyme A dehydrogenase, beta-hydroxyacyl-coenzyme A synthetase, beta-hydroxyacylcoenzyme A dehydrogenase, beta-hydroxybutyrylcoenzyme A dehydrogenase, 3-hydroxyacetyl-coenzyme A dehydrogenase, L-3-hydroxyacyl coenzyme A dehydrogenase, L-3-hydroxyacyl CoA dehydrogenase, beta-hydroxyacyl CoA dehydrogenase, 3beta-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxybutyryl-CoA dehydrogenase, beta-ketoacyl-CoA reductase, beta-hydroxy acid dehydrogenase, 3-L-hydroxyacyl-CoA dehydrogenase, 3-hydroxyisobutyryl-CoA dehydrogenase, 1-specific DPN-linked beta-hydroxybutyric dehydrogenase click to see details on this item	[m] : 3otdcoaName: 3-Oxotetradecanoyl-CoA Formula: C35H56N7O18P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item		3htdcoaName: (S)-3-Hydroxytetradecanoyl-CoA Formula: C35H58N7O18P3S Charge: -4 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	(B0272.3 | F54C8.1 | ech-8 | ech-9 | hacd-1) | (ech-1.2 | ech-1.1)	Fatty acid elongation
RM03858Name: Lauroyl-CoA:acetyl-CoA C-acyltransferase Type: Regular Location: Mitochondria KEGG ID: R03858 click to see details on this item	2.3.1.16Name: acetyl-CoA C-acyltransferase Other names: beta-ketothiolase, 3-ketoacyl-CoA thiolase, KAT, beta-ketoacyl coenzyme A thiolase, beta-ketoacyl-CoA thiolase, beta-ketoadipyl coenzyme A thiolase, beta-ketoadipyl-CoA thiolase, 3-ketoacyl CoA thiolase, 3-ketoacyl coenzyme A thiolase, 3-ketoacyl thiolase, 3-ketothiolase, 3-oxoacyl-CoA thiolase, 3-oxoacyl-coenzyme A thiolase, 6-oxoacyl-CoA thiolase, acetoacetyl-CoA beta-ketothiolase, acetyl-CoA acyltransferase, ketoacyl-CoA acyltransferase, ketoacyl-coenzyme A thiolase, long-chain 3-oxoacyl-CoA thiolase, oxoacyl-coenzyme A thiolase, pro-3-ketoacyl-CoA thiolase, thiolase I, 2-methylacetoacetyl-CoA thiolase [misleading] click to see details on this item	[m] : 3otdcoaName: 3-Oxotetradecanoyl-CoA Formula: C35H56N7O18P3S Charge: -4 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item		accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + ddcacoaName: Dodecanoyl-CoA (n-C12:0CoA) Formula: C33H54N7O17P3S Charge: -4 click to see details on this item	B0303.3 | acaa-2	Fatty acid elongation
RM04170Name: (S)-3-Hydroxydodecanoyl-CoA hydro-lyase Type: Regular Location: Mitochondria KEGG ID: R04170 click to see details on this item	4.2.1.17Name: enoyl-CoA hydratase Other names: enoyl hydrase, unsaturated acyl-CoA hydratase, beta-hydroxyacyl-CoA dehydrase, beta-hydroxyacid dehydrase, hydratase, enoyl coenzyme A, acyl coenzyme A hydrase, crotonase, crotonyl hydrase, 2-octenoyl coenzyme A hydrase, enoyl coenzyme A hydratase, 2-enoyl-CoA hydratase, short-chain enoyl-CoA hydratase, ECH, trans-2-enoyl-CoA hydratase, enoyl coenzyme A hydrase (D), enoyl coenzyme A hydrase (L), short chain enoyl coenzyme A hydratase, D-3-hydroxyacyl-CoA dehydratase, enol-CoA hydratase click to see details on this item	[m] : 3hddcoaName: (S)-3-Hydroxydodecanoyl-CoA Formula: C33H54N7O18P3S Charge: -4 click to see details on this item		dd2coaName: trans-Dodec-2-enoyl-CoA Formula: C33H52N7O17P3S Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	(ech-6 | ech-7) | (ech-1.2 | ech-1.1) | ech-3	Fatty acid elongation
RM04741Name: (S)-3-hydroxydodecanoyl-CoA:NAD+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R04741 click to see details on this item	1.1.1.211Name: long-chain-3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl-CoA dehydrogenase, long-chain 3-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase, LCHAD click to see details on this item 1.1.1.35Name: 3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl dehydrogenase, beta-keto-reductase, 3-keto reductase, 3-hydroxyacyl coenzyme A dehydrogenase, beta-hydroxyacyl-coenzyme A synthetase, beta-hydroxyacylcoenzyme A dehydrogenase, beta-hydroxybutyrylcoenzyme A dehydrogenase, 3-hydroxyacetyl-coenzyme A dehydrogenase, L-3-hydroxyacyl coenzyme A dehydrogenase, L-3-hydroxyacyl CoA dehydrogenase, beta-hydroxyacyl CoA dehydrogenase, 3beta-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxybutyryl-CoA dehydrogenase, beta-ketoacyl-CoA reductase, beta-hydroxy acid dehydrogenase, 3-L-hydroxyacyl-CoA dehydrogenase, 3-hydroxyisobutyryl-CoA dehydrogenase, 1-specific DPN-linked beta-hydroxybutyric dehydrogenase click to see details on this item	[m] : 3oddcoaName: 3-Oxododecanoyl-CoA Formula: C33H52N7O18P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item		3hddcoaName: (S)-3-Hydroxydodecanoyl-CoA Formula: C33H54N7O18P3S Charge: -4 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	(B0272.3 | F54C8.1 | ech-8 | ech-9 | hacd-1) | (ech-1.2 | ech-1.1)	Fatty acid elongation
RM04742Name: Decanoyl-CoA:acetyl-CoA C-acyltransferase Type: Regular Location: Mitochondria KEGG ID: R04742 click to see details on this item	2.3.1.16Name: acetyl-CoA C-acyltransferase Other names: beta-ketothiolase, 3-ketoacyl-CoA thiolase, KAT, beta-ketoacyl coenzyme A thiolase, beta-ketoacyl-CoA thiolase, beta-ketoadipyl coenzyme A thiolase, beta-ketoadipyl-CoA thiolase, 3-ketoacyl CoA thiolase, 3-ketoacyl coenzyme A thiolase, 3-ketoacyl thiolase, 3-ketothiolase, 3-oxoacyl-CoA thiolase, 3-oxoacyl-coenzyme A thiolase, 6-oxoacyl-CoA thiolase, acetoacetyl-CoA beta-ketothiolase, acetyl-CoA acyltransferase, ketoacyl-CoA acyltransferase, ketoacyl-coenzyme A thiolase, long-chain 3-oxoacyl-CoA thiolase, oxoacyl-coenzyme A thiolase, pro-3-ketoacyl-CoA thiolase, thiolase I, 2-methylacetoacetyl-CoA thiolase [misleading] click to see details on this item	[m] : 3oddcoaName: 3-Oxododecanoyl-CoA Formula: C33H52N7O18P3S Charge: -4 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item		accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + dcacoaName: Decanoyl-CoA (n-C10:0CoA) Formula: C31H50N7O17P3S Charge: -4 click to see details on this item	B0303.3 | acaa-2	Fatty acid elongation
RM04744Name: (S)-Hydroxydecanoyl-CoA hydro-lyase Type: Regular Location: Mitochondria KEGG ID: R04744 click to see details on this item	4.2.1.17Name: enoyl-CoA hydratase Other names: enoyl hydrase, unsaturated acyl-CoA hydratase, beta-hydroxyacyl-CoA dehydrase, beta-hydroxyacid dehydrase, hydratase, enoyl coenzyme A, acyl coenzyme A hydrase, crotonase, crotonyl hydrase, 2-octenoyl coenzyme A hydrase, enoyl coenzyme A hydratase, 2-enoyl-CoA hydratase, short-chain enoyl-CoA hydratase, ECH, trans-2-enoyl-CoA hydratase, enoyl coenzyme A hydrase (D), enoyl coenzyme A hydrase (L), short chain enoyl coenzyme A hydratase, D-3-hydroxyacyl-CoA dehydratase, enol-CoA hydratase click to see details on this item	[m] : 3hdcoaName: (S)-3-Hydroxydecanoyl-CoA Formula: C31H50N7O18P3S Charge: -4 click to see details on this item		dc2coaName: trans-Dec-2-enoyl-CoA Formula: C31H48N7O17P3S Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	(ech-6 | ech-7) | (ech-1.2 | ech-1.1) | ech-3	Fatty acid elongation
RM04743Name: (S)-hydroxydecanoyl-CoA:NAD+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R04743 click to see details on this item	1.1.1.211Name: long-chain-3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl-CoA dehydrogenase, long-chain 3-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase, LCHAD click to see details on this item 1.1.1.35Name: 3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl dehydrogenase, beta-keto-reductase, 3-keto reductase, 3-hydroxyacyl coenzyme A dehydrogenase, beta-hydroxyacyl-coenzyme A synthetase, beta-hydroxyacylcoenzyme A dehydrogenase, beta-hydroxybutyrylcoenzyme A dehydrogenase, 3-hydroxyacetyl-coenzyme A dehydrogenase, L-3-hydroxyacyl coenzyme A dehydrogenase, L-3-hydroxyacyl CoA dehydrogenase, beta-hydroxyacyl CoA dehydrogenase, 3beta-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxybutyryl-CoA dehydrogenase, beta-ketoacyl-CoA reductase, beta-hydroxy acid dehydrogenase, 3-L-hydroxyacyl-CoA dehydrogenase, 3-hydroxyisobutyryl-CoA dehydrogenase, 1-specific DPN-linked beta-hydroxybutyric dehydrogenase click to see details on this item	[m] : 3odcoaName: 3-Oxodecanoyl-CoA Formula: C31H48N7O18P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item		3hdcoaName: (S)-3-Hydroxydecanoyl-CoA Formula: C31H50N7O18P3S Charge: -4 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	(B0272.3 | F54C8.1 | ech-8 | ech-9 | hacd-1) | (ech-1.2 | ech-1.1)	Fatty acid elongation
RM03778Name: Octanoyl-CoA:acetyl-CoA C-acyltransferase Type: Regular Location: Mitochondria KEGG ID: R03778 click to see details on this item	2.3.1.16Name: acetyl-CoA C-acyltransferase Other names: beta-ketothiolase, 3-ketoacyl-CoA thiolase, KAT, beta-ketoacyl coenzyme A thiolase, beta-ketoacyl-CoA thiolase, beta-ketoadipyl coenzyme A thiolase, beta-ketoadipyl-CoA thiolase, 3-ketoacyl CoA thiolase, 3-ketoacyl coenzyme A thiolase, 3-ketoacyl thiolase, 3-ketothiolase, 3-oxoacyl-CoA thiolase, 3-oxoacyl-coenzyme A thiolase, 6-oxoacyl-CoA thiolase, acetoacetyl-CoA beta-ketothiolase, acetyl-CoA acyltransferase, ketoacyl-CoA acyltransferase, ketoacyl-coenzyme A thiolase, long-chain 3-oxoacyl-CoA thiolase, oxoacyl-coenzyme A thiolase, pro-3-ketoacyl-CoA thiolase, thiolase I, 2-methylacetoacetyl-CoA thiolase [misleading] click to see details on this item	[m] : 3odcoaName: 3-Oxodecanoyl-CoA Formula: C31H48N7O18P3S Charge: -4 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item		accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + occoaName: Octanoyl-CoA (n-C8:0CoA) Formula: C29H46N7O17P3S Charge: -4 click to see details on this item	B0303.3 | acaa-2	Fatty acid elongation
RM04746Name: (S)-Hydroxyoctanoyl-CoA hydro-lyase Type: Regular Location: Mitochondria KEGG ID: R04746 click to see details on this item	4.2.1.17Name: enoyl-CoA hydratase Other names: enoyl hydrase, unsaturated acyl-CoA hydratase, beta-hydroxyacyl-CoA dehydrase, beta-hydroxyacid dehydrase, hydratase, enoyl coenzyme A, acyl coenzyme A hydrase, crotonase, crotonyl hydrase, 2-octenoyl coenzyme A hydrase, enoyl coenzyme A hydratase, 2-enoyl-CoA hydratase, short-chain enoyl-CoA hydratase, ECH, trans-2-enoyl-CoA hydratase, enoyl coenzyme A hydrase (D), enoyl coenzyme A hydrase (L), short chain enoyl coenzyme A hydratase, D-3-hydroxyacyl-CoA dehydratase, enol-CoA hydratase click to see details on this item	[m] : 3hocoaName: (S)-3-Hydroxyoctanoyl-CoA Formula: C29H46N7O18P3S Charge: -4 click to see details on this item		h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + oc2coaName: trans-Oct-2-enoyl-CoA Formula: C29H44N7O17P3S Charge: -4 click to see details on this item	(ech-6 | ech-7) | (ech-1.2 | ech-1.1) | ech-3	Fatty acid elongation
RM04745Name: (S)-hydroxyoctanoyl-CoA:NAD+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R04745 click to see details on this item	1.1.1.211Name: long-chain-3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl-CoA dehydrogenase, long-chain 3-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase, LCHAD click to see details on this item 1.1.1.35Name: 3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl dehydrogenase, beta-keto-reductase, 3-keto reductase, 3-hydroxyacyl coenzyme A dehydrogenase, beta-hydroxyacyl-coenzyme A synthetase, beta-hydroxyacylcoenzyme A dehydrogenase, beta-hydroxybutyrylcoenzyme A dehydrogenase, 3-hydroxyacetyl-coenzyme A dehydrogenase, L-3-hydroxyacyl coenzyme A dehydrogenase, L-3-hydroxyacyl CoA dehydrogenase, beta-hydroxyacyl CoA dehydrogenase, 3beta-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxybutyryl-CoA dehydrogenase, beta-ketoacyl-CoA reductase, beta-hydroxy acid dehydrogenase, 3-L-hydroxyacyl-CoA dehydrogenase, 3-hydroxyisobutyryl-CoA dehydrogenase, 1-specific DPN-linked beta-hydroxybutyric dehydrogenase click to see details on this item	[m] : 3oocoaName: 3-Oxooctanoyl-CoA Formula: C29H44N7O18P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item		3hocoaName: (S)-3-Hydroxyoctanoyl-CoA Formula: C29H46N7O18P3S Charge: -4 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	(B0272.3 | F54C8.1 | ech-8 | ech-9 | hacd-1) | (ech-1.2 | ech-1.1)	Fatty acid elongation
RM04747Name: Hexanoyl-CoA:acetyl-CoA C-acyltransferase Type: Regular Location: Mitochondria KEGG ID: R04747 click to see details on this item	2.3.1.16Name: acetyl-CoA C-acyltransferase Other names: beta-ketothiolase, 3-ketoacyl-CoA thiolase, KAT, beta-ketoacyl coenzyme A thiolase, beta-ketoacyl-CoA thiolase, beta-ketoadipyl coenzyme A thiolase, beta-ketoadipyl-CoA thiolase, 3-ketoacyl CoA thiolase, 3-ketoacyl coenzyme A thiolase, 3-ketoacyl thiolase, 3-ketothiolase, 3-oxoacyl-CoA thiolase, 3-oxoacyl-coenzyme A thiolase, 6-oxoacyl-CoA thiolase, acetoacetyl-CoA beta-ketothiolase, acetyl-CoA acyltransferase, ketoacyl-CoA acyltransferase, ketoacyl-coenzyme A thiolase, long-chain 3-oxoacyl-CoA thiolase, oxoacyl-coenzyme A thiolase, pro-3-ketoacyl-CoA thiolase, thiolase I, 2-methylacetoacetyl-CoA thiolase [misleading] click to see details on this item	[m] : 3oocoaName: 3-Oxooctanoyl-CoA Formula: C29H44N7O18P3S Charge: -4 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item		accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + hxcoaName: Hexanoyl-CoA (n-C6:0CoA) Formula: C27H42N7O17P3S Charge: -4 click to see details on this item	B0303.3 | acaa-2	Fatty acid elongation
RM04749Name: (S)-Hydroxyhexanoyl-CoA hydro-lyase Type: Regular Location: Mitochondria KEGG ID: R04749 click to see details on this item	4.2.1.17Name: enoyl-CoA hydratase Other names: enoyl hydrase, unsaturated acyl-CoA hydratase, beta-hydroxyacyl-CoA dehydrase, beta-hydroxyacid dehydrase, hydratase, enoyl coenzyme A, acyl coenzyme A hydrase, crotonase, crotonyl hydrase, 2-octenoyl coenzyme A hydrase, enoyl coenzyme A hydratase, 2-enoyl-CoA hydratase, short-chain enoyl-CoA hydratase, ECH, trans-2-enoyl-CoA hydratase, enoyl coenzyme A hydrase (D), enoyl coenzyme A hydrase (L), short chain enoyl coenzyme A hydratase, D-3-hydroxyacyl-CoA dehydratase, enol-CoA hydratase click to see details on this item	[m] : 3hhcoaName: (S)-3-Hydroxyhexanoyl-CoA Formula: C27H42N7O18P3S Charge: -4 click to see details on this item		h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + hx2coaName: trans-Hex-2-enoyl-CoA Formula: C27H40N7O17P3S Charge: -4 click to see details on this item	(ech-6 | ech-7) | (ech-1.2 | ech-1.1) | ech-3	Fatty acid elongation
RM04748Name: (S)-hydroxyhexanoyl-CoA:NAD+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R04748 click to see details on this item	1.1.1.211Name: long-chain-3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl-CoA dehydrogenase, long-chain 3-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase, LCHAD click to see details on this item 1.1.1.35Name: 3-hydroxyacyl-CoA dehydrogenase Other names: beta-hydroxyacyl dehydrogenase, beta-keto-reductase, 3-keto reductase, 3-hydroxyacyl coenzyme A dehydrogenase, beta-hydroxyacyl-coenzyme A synthetase, beta-hydroxyacylcoenzyme A dehydrogenase, beta-hydroxybutyrylcoenzyme A dehydrogenase, 3-hydroxyacetyl-coenzyme A dehydrogenase, L-3-hydroxyacyl coenzyme A dehydrogenase, L-3-hydroxyacyl CoA dehydrogenase, beta-hydroxyacyl CoA dehydrogenase, 3beta-hydroxyacyl coenzyme A dehydrogenase, 3-hydroxybutyryl-CoA dehydrogenase, beta-ketoacyl-CoA reductase, beta-hydroxy acid dehydrogenase, 3-L-hydroxyacyl-CoA dehydrogenase, 3-hydroxyisobutyryl-CoA dehydrogenase, 1-specific DPN-linked beta-hydroxybutyric dehydrogenase click to see details on this item	[m] : 3ohcoaName: 3-Oxohexanoyl-CoA Formula: C27H40N7O18P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item		3hhcoaName: (S)-3-Hydroxyhexanoyl-CoA Formula: C27H42N7O18P3S Charge: -4 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	(B0272.3 | F54C8.1 | ech-8 | ech-9 | hacd-1) | (ech-1.2 | ech-1.1)	Fatty acid elongation
RM01177Name: butanoyl-CoA:acetyl-CoA C-butanoyltransferase Type: Regular Location: Mitochondria KEGG ID: R01177 click to see details on this item	2.3.1.16Name: acetyl-CoA C-acyltransferase Other names: beta-ketothiolase, 3-ketoacyl-CoA thiolase, KAT, beta-ketoacyl coenzyme A thiolase, beta-ketoacyl-CoA thiolase, beta-ketoadipyl coenzyme A thiolase, beta-ketoadipyl-CoA thiolase, 3-ketoacyl CoA thiolase, 3-ketoacyl coenzyme A thiolase, 3-ketoacyl thiolase, 3-ketothiolase, 3-oxoacyl-CoA thiolase, 3-oxoacyl-coenzyme A thiolase, 6-oxoacyl-CoA thiolase, acetoacetyl-CoA beta-ketothiolase, acetyl-CoA acyltransferase, ketoacyl-CoA acyltransferase, ketoacyl-coenzyme A thiolase, long-chain 3-oxoacyl-CoA thiolase, oxoacyl-coenzyme A thiolase, pro-3-ketoacyl-CoA thiolase, thiolase I, 2-methylacetoacetyl-CoA thiolase [misleading] click to see details on this item 2.3.1.9Name: acetyl-CoA C-acetyltransferase Other names: acetoacetyl-CoA thiolase, beta-acetoacetyl coenzyme A thiolase, 2-methylacetoacetyl-CoA thiolase [misleading], 3-oxothiolase, acetyl coenzyme A thiolase, acetyl-CoA acetyltransferase, acetyl-CoA:N-acetyltransferase, thiolase II click to see details on this item	[m] : 3ohcoaName: 3-Oxohexanoyl-CoA Formula: C27H40N7O18P3S Charge: -4 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item		accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + btcoaName: Butanoyl-CoA Formula: C25H38N7O17P3S Charge: -4 click to see details on this item	(B0303.3 | acaa-2) | (T02G5.7 | kat-1)	Fatty acid elongation
RM06985Name: trans-Hex-2-enoyl-CoA reductase Type: Regular Location: Mitochondria KEGG ID: R06985 click to see details on this item	1.3.1.38Name: trans-2-enoyl-CoA reductase (NADPH) Other names: NADPH-dependent trans-2-enoyl-CoA reductase, reductase, trans-enoyl coenzyme A, trans-2-enoyl-CoA reductase (NADPH2) click to see details on this item	[m] : hName: H+ Formula: H Charge: 1 click to see details on this item + hx2coaName: trans-Hex-2-enoyl-CoA Formula: C27H40N7O17P3S Charge: -4 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item		hxcoaName: Hexanoyl-CoA (n-C6:0CoA) Formula: C27H42N7O17P3S Charge: -4 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item	mecr-1 | Y48A6B.9	Fatty acid elongation
RM03776Name: trans-Oct-2-enoyl-CoA reductase Type: Regular Location: Mitochondria KEGG ID: R03776 click to see details on this item	1.3.1.38Name: trans-2-enoyl-CoA reductase (NADPH) Other names: NADPH-dependent trans-2-enoyl-CoA reductase, reductase, trans-enoyl coenzyme A, trans-2-enoyl-CoA reductase (NADPH2) click to see details on this item	[m] : hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + oc2coaName: trans-Oct-2-enoyl-CoA Formula: C29H44N7O17P3S Charge: -4 click to see details on this item		nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + occoaName: Octanoyl-CoA (n-C8:0CoA) Formula: C29H46N7O17P3S Charge: -4 click to see details on this item	mecr-1 | Y48A6B.9	Fatty acid elongation
RM04753Name: trans-Dec-2-enoyl-CoA reductase Type: Regular Location: Mitochondria KEGG ID: R04753 click to see details on this item	1.3.1.38Name: trans-2-enoyl-CoA reductase (NADPH) Other names: NADPH-dependent trans-2-enoyl-CoA reductase, reductase, trans-enoyl coenzyme A, trans-2-enoyl-CoA reductase (NADPH2) click to see details on this item	[m] : dc2coaName: trans-Dec-2-enoyl-CoA Formula: C31H48N7O17P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item		dcacoaName: Decanoyl-CoA (n-C10:0CoA) Formula: C31H50N7O17P3S Charge: -4 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item	mecr-1 | Y48A6B.9	Fatty acid elongation
RM03856Name: trans-Dodec-2-enoyl-CoA reductase Type: Regular Location: Mitochondria KEGG ID: R03856 click to see details on this item	1.3.1.38Name: trans-2-enoyl-CoA reductase (NADPH) Other names: NADPH-dependent trans-2-enoyl-CoA reductase, reductase, trans-enoyl coenzyme A, trans-2-enoyl-CoA reductase (NADPH2) click to see details on this item	[m] : dd2coaName: trans-Dodec-2-enoyl-CoA Formula: C33H52N7O17P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item		ddcacoaName: Dodecanoyl-CoA (n-C12:0CoA) Formula: C33H54N7O17P3S Charge: -4 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item	mecr-1 | Y48A6B.9	Fatty acid elongation
RM03989Name: trans-Tetradec-2-enoyl-CoA reductase Type: Regular Location: Mitochondria KEGG ID: R03989 click to see details on this item	1.3.1.38Name: trans-2-enoyl-CoA reductase (NADPH) Other names: NADPH-dependent trans-2-enoyl-CoA reductase, reductase, trans-enoyl coenzyme A, trans-2-enoyl-CoA reductase (NADPH2) click to see details on this item	[m] : hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + td2coaName: trans-Tetradec-2-enoyl-CoA Formula: C35H56N7O17P3S Charge: -4 click to see details on this item		nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + tdcoaName: Tetradecanoyl-CoA (n-C14:0CoA) Formula: C35H58N7O17P3S Charge: -4 click to see details on this item	mecr-1 | Y48A6B.9	Fatty acid elongation
RM01278Name: hexadecanoyl-CoA:NADP+ trans-2-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R01278 click to see details on this item	1.3.1.38Name: trans-2-enoyl-CoA reductase (NADPH) Other names: NADPH-dependent trans-2-enoyl-CoA reductase, reductase, trans-enoyl coenzyme A, trans-2-enoyl-CoA reductase (NADPH2) click to see details on this item	[m] : hName: H+ Formula: H Charge: 1 click to see details on this item + hdd2coaName: trans-Hexadec-2-enoyl-CoA Formula: C37H60N7O17P3S Charge: -4 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item		nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + pmtcoaName: Palmitoyl-CoA (n-C16:0CoA) Formula: C37H62N7O17P3S Charge: -4 click to see details on this item	mecr-1 | Y48A6B.9	Fatty acid elongation
RC07758Name: very-long-chain 3-oxoacyl-CoA synthase Type: Regular Location: Cytosol KEGG ID: R07758 click to see details on this item	2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name) click to see details on this item	[c] : malcoaName: Malonyl-CoA Formula: C24H33N7O19P3S Charge: -5 click to see details on this item + pmtcoaName: Palmitoyl-CoA (n-C16:0CoA) Formula: C37H62N7O17P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		3oodcoaName: 3-Oxooctadecanoyl-CoA Formula: C39H64N7O18P3S Charge: -4 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	elo-1	Fatty acid elongation
RC07759Name: very-long-chain 3-oxoacyl-CoA reductase Type: Regular Location: Cytosol KEGG ID: R07759 click to see details on this item	1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name) click to see details on this item	[c] : 3oodcoaName: 3-Oxooctadecanoyl-CoA Formula: C39H64N7O18P3S Charge: -4 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		3hodcoaName: (S)-3-Hydroxyoctadecanoyl-CoA Formula: C39H66N7O18P3S Charge: -4 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item	let-767	Fatty acid elongation
RC07760Name: 3-hydroxyacyl-CoA dehydratase 2 Type: Regular Location: Cytosol KEGG ID: R07760 click to see details on this item	4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase Other names: PHS1 (gene name), PAS2 (gene name) click to see details on this item	[c] : 3hodcoaName: (S)-3-Hydroxyoctadecanoyl-CoA Formula: C39H66N7O18P3S Charge: -4 click to see details on this item		h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + od2coaName: trans-Octadec-2-enoyl-CoA Formula: C39H64N7O17P3S Charge: -4 click to see details on this item	hpo-8	Fatty acid elongation
RC07761Name: very-long-chain enoyl-CoA reductase Type: Regular Location: Cytosol KEGG ID: R07761 click to see details on this item	1.3.1.93Name: very-long-chain enoyl-CoA reductase Other names: TSC13 (gene name), CER10 (gene name) click to see details on this item	[c] : od2coaName: trans-Octadec-2-enoyl-CoA Formula: C39H64N7O17P3S Charge: -4 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		stcoaName: Stearoyl-CoA (n-C18:0CoA) Formula: C39H66N7O17P3S Charge: -4 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item	art-1	Fatty acid elongation
RCC0124Name: merged fatty acid elongation (C18 to C24) Type: Regular Location: Cytosol KEGG ID: R10825;R10826;R10827;R10828 click to see details on this item	2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name) click to see details on this item 1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name) click to see details on this item 4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase Other names: PHS1 (gene name), PAS2 (gene name) click to see details on this item 1.3.1.93Name: very-long-chain enoyl-CoA reductase Other names: TSC13 (gene name), CER10 (gene name) click to see details on this item	[c] : (9) hName: H+ Formula: H Charge: 1 click to see details on this item + (3) malcoaName: Malonyl-CoA Formula: C24H33N7O19P3S Charge: -5 click to see details on this item + (6) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + stcoaName: Stearoyl-CoA (n-C18:0CoA) Formula: C39H66N7O17P3S Charge: -4 click to see details on this item		(3) co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + (3) coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + (3) h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + (6) nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + lgnccoaName: lignocericyl coenzyme A Formula: C45H78N7O17P3S Charge: -4 click to see details on this item	elo-1 & let-767 & hpo-8 & art-1	Fatty acid elongation
RC01274Name: Palmitoyl-CoA hydrolase Type: Regular Location: Cytosol KEGG ID: R01274 click to see details on this item	3.1.2.22Name: palmitoyl[protein] hydrolase Other names: palmitoyl-protein thioesterase, palmitoyl-(protein) hydrolase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + pmtcoaName: Palmitoyl-CoA (n-C16:0CoA) Formula: C37H62N7O17P3S Charge: -4 click to see details on this item		coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + hdcaName: Hexadecanoate (n-C16:0) Formula: C16H31O2 Charge: -1 click to see details on this item	ppt-1	Fatty acid elongation

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