WormFlux: mechanistic analysis of C. elegans metabolism

HOME DOWNLOAD CITATION HELP

(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	mettrna
Name .....................................................	:	L-Methionyl-tRNA (Met), etc.L-Methionyl-tRNA, L-Methionyl-tRNA(Met)
Model ID .....................................................	:	C02430
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C02430
Formula .....................................................	:	C5H11NO2SR
Charge .....................................................	:	+1
Localization .....................................................	:	Mitochondria, Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	mettrna
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Not yet represented in WormPaths maps.

iCEL1314

Comments

TRNA formula in BiGG was modified for mass balance.

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC03659Name: L-Methionine:tRNAMet ligase (AMP-forming) Type: Regular Location: Cytosol KEGG ID: R03659 click to see details on this item	6.1.1.10Name: methionine---tRNA ligase Other names: methionyl-tRNA synthetase, methionyl-transfer ribonucleic acid synthetase, methionyl-transfer ribonucleate synthetase, methionyl-transfer RNA synthetase, methionine translase, MetRS click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + met-LName: L-Methionine Formula: C5H11NO2S Charge: 0 click to see details on this item + trnametName: tRNA(Met) Formula: ROH Charge: 0 click to see details on this item		ampName: AMP Formula: C10H12N5O7P Charge: -2 click to see details on this item + mettrnaName: L-Methionyl-tRNA (Met) Formula: C5H11NO2SR Charge: 1 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	mars-1 \| Y105E8A.20	Aminoacyl-tRNA biosynthesis
RM03659Name: L-Methionine:tRNAMet ligase (AMP-forming) Type: Regular Location: Mitochondria KEGG ID: R03659 click to see details on this item	6.1.1.10Name: methionine---tRNA ligase Other names: methionyl-tRNA synthetase, methionyl-transfer ribonucleic acid synthetase, methionyl-transfer ribonucleate synthetase, methionyl-transfer RNA synthetase, methionine translase, MetRS click to see details on this item	[m] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + met-LName: L-Methionine Formula: C5H11NO2S Charge: 0 click to see details on this item + trnametName: tRNA(Met) Formula: ROH Charge: 0 click to see details on this item		ampName: AMP Formula: C10H12N5O7P Charge: -2 click to see details on this item + mettrnaName: L-Methionyl-tRNA (Met) Formula: C5H11NO2SR Charge: 1 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	Y105E8A.20	Aminoacyl-tRNA biosynthesis
RCC0170Name: Procollagen synthesis (unmodified protein) Type: Regular Location: Cytosol KEGG ID: NA click to see details on this item	Not applicable	[c] : (2.0) gtpName: GTP Formula: C10H12N5O14P3 Charge: -4 click to see details on this item + (0.324) atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + (2.324) h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + (0.072072) alatrnaName: L-Alanyl-tRNA(Ala) Formula: C3H7NO2R Charge: 1 click to see details on this item + (0.048116) argtrnaName: L-Arginyl-tRNA(Arg) Formula: C6H15N4O2R Charge: 2 click to see details on this item + (0.033015) asntrnaName: L-Asparaginyl-tRNA(Asn) Formula: C4H8N2O3R Charge: 1 click to see details on this item + (0.049284) asptrnaName: L-Aspartyl-tRNA(Asp) Formula: C4H6NO4R Charge: 0 click to see details on this item + (0.027047) cystrnaName: L-Cysteinyl-tRNA(Cys) Formula: C3H7NO2SR Charge: 1 click to see details on this item + (0.049537) glutrnaName: L-Glutamyl-tRNA(Glu) Formula: C5H8NO4R Charge: 0 click to see details on this item + (0.046288) glntrnaName: L-Glutaminyl-tRNA(Gln) Formula: C5H10N2O3R Charge: 1 click to see details on this item + (0.195952) glytrnaName: Glycyl-tRNA(Gly) Formula: C2H5NO2R Charge: 1 click to see details on this item + (0.014203) histrnaName: L-Histidyl-tRNA(His) Formula: C6H9N3O2R Charge: 1 click to see details on this item + (0.027694) iletrnaName: L-Isoleucyl-tRNA(Ile) Formula: C6H13NO2R Charge: 1 click to see details on this item + (0.033232) leutrnaName: L-Leucyl-tRNA(Leu) Formula: C6H13NO2R Charge: 1 click to see details on this item + (0.036365) lystrnaName: L-Lysine-tRNA (Lys) Formula: C6H15N2O2R Charge: 2 click to see details on this item + (0.017249) mettrnaName: L-Methionyl-tRNA (Met) Formula: C5H11NO2SR Charge: 1 click to see details on this item + (0.017276) phetrnaName: L-Phenylalanyl-tRNA(Phe) Formula: C9H11NO2R Charge: 1 click to see details on this item + (0.167533) protrnaName: L-Prolyl-tRNA(Pro) Formula: C5H9NO2R Charge: 1 click to see details on this item + (0.051072) sertrnaName: L-Seryl-tRNA(Ser) Formula: C3H7NO3R Charge: 1 click to see details on this item + (0.042924) thrtrnaName: L-Threonyl-tRNA(Thr) Formula: C4H9NO3R Charge: 1 click to see details on this item + (0.004785) trptrnaName: L-Tryptophanyl-tRNA(Trp) Formula: C11H12N2O2R Charge: 1 click to see details on this item + (0.022921) tyrtrnaName: L-Tyrosyl-tRNA(Tyr) Formula: C9H11NO3R Charge: 1 click to see details on this item + (0.043435) valtrnaName: L-Valyl-tRNA(Val) Formula: C5H11NO2R Charge: 1 click to see details on this item		(0.921682) pcollg_restName: Procollagen (unmodified portion) Formula: X Charge: 0 click to see details on this item + (0.006239) pcollglysName: Procollagen L-lysine (to be modified) Formula: XH Charge: 1 click to see details on this item + (0.072079) pcollgproName: Procollagen L-proline (to be modified) Formula: XH Charge: 0 click to see details on this item + (2.0) gdpName: GDP Formula: C10H12N5O11P2 Charge: -3 click to see details on this item + (0.324) adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + (3.324) hName: H+ Formula: H Charge: 1 click to see details on this item + (2.324) piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item + (0.072072) trnaalaName: tRNA(Ala) Formula: ROH Charge: 0 click to see details on this item + (0.048116) trnaargName: tRNA(Arg) Formula: ROH Charge: 0 click to see details on this item + (0.033015) trnaasnName: tRNA(Asn) Formula: ROH Charge: 0 click to see details on this item + (0.049284) trnaaspName: tRNA(Asp) Formula: ROH Charge: 0 click to see details on this item + (0.027047) trnacysName: tRNA(Cys) Formula: ROH Charge: 0 click to see details on this item + (0.049537) trnagluName: tRNA (Glu) Formula: ROH Charge: 0 click to see details on this item + (0.046288) trnaglnName: tRNA(Gln) Formula: ROH Charge: 0 click to see details on this item + (0.195952) trnaglyName: tRNA(Gly) Formula: ROH Charge: 0 click to see details on this item + (0.014203) trnahisName: tRNA(His) Formula: ROH Charge: 0 click to see details on this item + (0.027694) trnaileName: tRNA(Ile) Formula: ROH Charge: 0 click to see details on this item + (0.033232) trnaleuName: tRNA(Leu) Formula: ROH Charge: 0 click to see details on this item + (0.036365) trnalysName: tRNA(Lys) Formula: ROH Charge: 0 click to see details on this item + (0.017249) trnametName: tRNA(Met) Formula: ROH Charge: 0 click to see details on this item + (0.017276) trnapheName: tRNA(Phe) Formula: ROH Charge: 0 click to see details on this item + (0.167533) trnaproName: tRNA(Pro) Formula: ROH Charge: 0 click to see details on this item + (0.051072) trnaserName: tRNA(Ser) Formula: ROH Charge: 0 click to see details on this item + (0.042924) trnathrName: tRNA(Thr) Formula: ROH Charge: 0 click to see details on this item + (0.004785) trnatrpName: tRNA(Trp) Formula: ROH Charge: 0 click to see details on this item + (0.022921) trnatyrName: tRNA(Tyr) Formula: ROH Charge: 0 click to see details on this item + (0.043435) trnavalName: tRNA(Val) Formula: ROH Charge: 0 click to see details on this item	Not applicable	Miscellaneous
BIO0001Name: Protein synthesis (mitochondrial) Type: Biomass Location: Mitochondria KEGG ID: NA click to see details on this item	Not applicable	[m] : (2.0) gtpName: GTP Formula: C10H12N5O14P3 Charge: -4 click to see details on this item + (0.324) atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + (2.324) h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + (0.111867) alatrnaName: L-Alanyl-tRNA(Ala) Formula: C3H7NO2R Charge: 1 click to see details on this item + (0.048846) argtrnaName: L-Arginyl-tRNA(Arg) Formula: C6H15N4O2R Charge: 2 click to see details on this item + (0.035405) asntrnaName: L-Asparaginyl-tRNA(Asn) Formula: C4H8N2O3R Charge: 1 click to see details on this item + (0.064946) asptrnaName: L-Aspartyl-tRNA(Asp) Formula: C4H6NO4R Charge: 0 click to see details on this item + (0.008665) cystrnaName: L-Cysteinyl-tRNA(Cys) Formula: C3H7NO2SR Charge: 1 click to see details on this item + (0.067386) glutrnaName: L-Glutamyl-tRNA(Glu) Formula: C5H8NO4R Charge: 0 click to see details on this item + (0.037694) glntrnaName: L-Glutaminyl-tRNA(Gln) Formula: C5H10N2O3R Charge: 1 click to see details on this item + (0.094618) glytrnaName: Glycyl-tRNA(Gly) Formula: C2H5NO2R Charge: 1 click to see details on this item + (0.01782) histrnaName: L-Histidyl-tRNA(His) Formula: C6H9N3O2R Charge: 1 click to see details on this item + (0.053231) iletrnaName: L-Isoleucyl-tRNA(Ile) Formula: C6H13NO2R Charge: 1 click to see details on this item + (0.082051) leutrnaName: L-Leucyl-tRNA(Leu) Formula: C6H13NO2R Charge: 1 click to see details on this item + (0.071622) lystrnaName: L-Lysine-tRNA (Lys) Formula: C6H15N2O2R Charge: 2 click to see details on this item + (0.020458) mettrnaName: L-Methionyl-tRNA (Met) Formula: C5H11NO2SR Charge: 1 click to see details on this item + (0.035592) phetrnaName: L-Phenylalanyl-tRNA(Phe) Formula: C9H11NO2R Charge: 1 click to see details on this item + (0.043238) protrnaName: L-Prolyl-tRNA(Pro) Formula: C5H9NO2R Charge: 1 click to see details on this item + (0.045815) sertrnaName: L-Seryl-tRNA(Ser) Formula: C3H7NO3R Charge: 1 click to see details on this item + (0.049868) thrtrnaName: L-Threonyl-tRNA(Thr) Formula: C4H9NO3R Charge: 1 click to see details on this item + (0.008944) trptrnaName: L-Tryptophanyl-tRNA(Trp) Formula: C11H12N2O2R Charge: 1 click to see details on this item + (0.026832) tyrtrnaName: L-Tyrosyl-tRNA(Tyr) Formula: C9H11NO3R Charge: 1 click to see details on this item + (0.075105) valtrnaName: L-Valyl-tRNA(Val) Formula: C5H11NO2R Charge: 1 click to see details on this item		prot_mitoName: Mitochondrial protein Formula: X Charge: 0 click to see details on this item + (2.0) gdpName: GDP Formula: C10H12N5O11P2 Charge: -3 click to see details on this item + (0.324) adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + (3.324) hName: H+ Formula: H Charge: 1 click to see details on this item + (2.324) piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item + (0.111867) trnaalaName: tRNA(Ala) Formula: ROH Charge: 0 click to see details on this item + (0.048846) trnaargName: tRNA(Arg) Formula: ROH Charge: 0 click to see details on this item + (0.035405) trnaasnName: tRNA(Asn) Formula: ROH Charge: 0 click to see details on this item + (0.064946) trnaaspName: tRNA(Asp) Formula: ROH Charge: 0 click to see details on this item + (0.008665) trnacysName: tRNA(Cys) Formula: ROH Charge: 0 click to see details on this item + (0.067386) trnagluName: tRNA (Glu) Formula: ROH Charge: 0 click to see details on this item + (0.037694) trnaglnName: tRNA(Gln) Formula: ROH Charge: 0 click to see details on this item + (0.094618) trnaglyName: tRNA(Gly) Formula: ROH Charge: 0 click to see details on this item + (0.01782) trnahisName: tRNA(His) Formula: ROH Charge: 0 click to see details on this item + (0.053231) trnaileName: tRNA(Ile) Formula: ROH Charge: 0 click to see details on this item + (0.082051) trnaleuName: tRNA(Leu) Formula: ROH Charge: 0 click to see details on this item + (0.071622) trnalysName: tRNA(Lys) Formula: ROH Charge: 0 click to see details on this item + (0.020458) trnametName: tRNA(Met) Formula: ROH Charge: 0 click to see details on this item + (0.035592) trnapheName: tRNA(Phe) Formula: ROH Charge: 0 click to see details on this item + (0.043238) trnaproName: tRNA(Pro) Formula: ROH Charge: 0 click to see details on this item + (0.045815) trnaserName: tRNA(Ser) Formula: ROH Charge: 0 click to see details on this item + (0.049868) trnathrName: tRNA(Thr) Formula: ROH Charge: 0 click to see details on this item + (0.008944) trnatrpName: tRNA(Trp) Formula: ROH Charge: 0 click to see details on this item + (0.026832) trnatyrName: tRNA(Tyr) Formula: ROH Charge: 0 click to see details on this item + (0.075105) trnavalName: tRNA(Val) Formula: ROH Charge: 0 click to see details on this item	Not applicable	Biomass assembly
BIO0002Name: Protein synthesis (cytoplasmic) Type: Biomass Location: Cytosol KEGG ID: NA click to see details on this item	Not applicable	[c] : (2.0) gtpName: GTP Formula: C10H12N5O14P3 Charge: -4 click to see details on this item + (0.324) atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + (2.324) h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + (0.12769) alatrnaName: L-Alanyl-tRNA(Ala) Formula: C3H7NO2R Charge: 1 click to see details on this item + (0.042387) argtrnaName: L-Arginyl-tRNA(Arg) Formula: C6H15N4O2R Charge: 2 click to see details on this item + (0.025739) asntrnaName: L-Asparaginyl-tRNA(Asn) Formula: C4H8N2O3R Charge: 1 click to see details on this item + (0.084822) asptrnaName: L-Aspartyl-tRNA(Asp) Formula: C4H6NO4R Charge: 0 click to see details on this item + (0.000208) cystrnaName: L-Cysteinyl-tRNA(Cys) Formula: C3H7NO2SR Charge: 1 click to see details on this item + (0.085568) glutrnaName: L-Glutamyl-tRNA(Glu) Formula: C5H8NO4R Charge: 0 click to see details on this item + (0.026184) glntrnaName: L-Glutaminyl-tRNA(Gln) Formula: C5H10N2O3R Charge: 1 click to see details on this item + (0.074691) glytrnaName: Glycyl-tRNA(Gly) Formula: C2H5NO2R Charge: 1 click to see details on this item + (0.017927) histrnaName: L-Histidyl-tRNA(His) Formula: C6H9N3O2R Charge: 1 click to see details on this item + (0.052143) iletrnaName: L-Isoleucyl-tRNA(Ile) Formula: C6H13NO2R Charge: 1 click to see details on this item + (0.079867) leutrnaName: L-Leucyl-tRNA(Leu) Formula: C6H13NO2R Charge: 1 click to see details on this item + (0.079083) lystrnaName: L-Lysine-tRNA (Lys) Formula: C6H15N2O2R Charge: 2 click to see details on this item + (0.012181) mettrnaName: L-Methionyl-tRNA (Met) Formula: C5H11NO2SR Charge: 1 click to see details on this item + (0.036544) phetrnaName: L-Phenylalanyl-tRNA(Phe) Formula: C9H11NO2R Charge: 1 click to see details on this item + (0.045145) protrnaName: L-Prolyl-tRNA(Pro) Formula: C5H9NO2R Charge: 1 click to see details on this item + (0.051284) sertrnaName: L-Seryl-tRNA(Ser) Formula: C3H7NO3R Charge: 1 click to see details on this item + (0.052305) thrtrnaName: L-Threonyl-tRNA(Thr) Formula: C4H9NO3R Charge: 1 click to see details on this item + (0.007259) trptrnaName: L-Tryptophanyl-tRNA(Trp) Formula: C11H12N2O2R Charge: 1 click to see details on this item + (0.027882) tyrtrnaName: L-Tyrosyl-tRNA(Tyr) Formula: C9H11NO3R Charge: 1 click to see details on this item + (0.071091) valtrnaName: L-Valyl-tRNA(Val) Formula: C5H11NO2R Charge: 1 click to see details on this item		prot_otherName: Non-mitochondrial protein Formula: X Charge: 0 click to see details on this item + (2.0) gdpName: GDP Formula: C10H12N5O11P2 Charge: -3 click to see details on this item + (0.324) adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + (3.324) hName: H+ Formula: H Charge: 1 click to see details on this item + (2.324) piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item + (0.12769) trnaalaName: tRNA(Ala) Formula: ROH Charge: 0 click to see details on this item + (0.042387) trnaargName: tRNA(Arg) Formula: ROH Charge: 0 click to see details on this item + (0.025739) trnaasnName: tRNA(Asn) Formula: ROH Charge: 0 click to see details on this item + (0.084822) trnaaspName: tRNA(Asp) Formula: ROH Charge: 0 click to see details on this item + (0.000208) trnacysName: tRNA(Cys) Formula: ROH Charge: 0 click to see details on this item + (0.085568) trnagluName: tRNA (Glu) Formula: ROH Charge: 0 click to see details on this item + (0.026184) trnaglnName: tRNA(Gln) Formula: ROH Charge: 0 click to see details on this item + (0.074691) trnaglyName: tRNA(Gly) Formula: ROH Charge: 0 click to see details on this item + (0.017927) trnahisName: tRNA(His) Formula: ROH Charge: 0 click to see details on this item + (0.052143) trnaileName: tRNA(Ile) Formula: ROH Charge: 0 click to see details on this item + (0.079867) trnaleuName: tRNA(Leu) Formula: ROH Charge: 0 click to see details on this item + (0.079083) trnalysName: tRNA(Lys) Formula: ROH Charge: 0 click to see details on this item + (0.012181) trnametName: tRNA(Met) Formula: ROH Charge: 0 click to see details on this item + (0.036544) trnapheName: tRNA(Phe) Formula: ROH Charge: 0 click to see details on this item + (0.045145) trnaproName: tRNA(Pro) Formula: ROH Charge: 0 click to see details on this item + (0.051284) trnaserName: tRNA(Ser) Formula: ROH Charge: 0 click to see details on this item + (0.052305) trnathrName: tRNA(Thr) Formula: ROH Charge: 0 click to see details on this item + (0.007259) trnatrpName: tRNA(Trp) Formula: ROH Charge: 0 click to see details on this item + (0.027882) trnatyrName: tRNA(Tyr) Formula: ROH Charge: 0 click to see details on this item + (0.071091) trnavalName: tRNA(Val) Formula: ROH Charge: 0 click to see details on this item	Not applicable	Biomass assembly

The information and tools provided in this website are to be used for academic purposes only.