Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	L2aadp6sa
Name .....................................................	:	L-2-Aminoadipate 6-semialdehyde, etc.2-Aminoadipate 6-semialdehyde, L-Allysine, Allysine, (S)-2-Amino-6-oxohexanoate
Model ID .....................................................	:	C04076
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C04076
Formula .....................................................	:	C6H11NO3
Charge .....................................................	:	0
Localization .....................................................	:	Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	L2aadp6sa
Other associations .....................................................	:	See reaction table below.
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Lysine degradation (m)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM02313Name: N6-(L-1,3-Dicarboxypropyl)-L-lysine:NAD+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R02313 click to see details on this item	1.5.1.9Name: saccharopine dehydrogenase (NAD+, L-glutamate-forming) Other names: dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, glutamate-forming), saccharopin dehydrogenase, NAD+ oxidoreductase (L-2-aminoadipic-delta-semialdehyde and glutamate forming), aminoadipic semialdehyde synthase, 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming) click to see details on this item	[m] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + saccrp-LName: L-Saccharopine Formula: C11H19N2O6 Charge: -1 click to see details on this item		L2aadp6saName: L-2-Aminoadipate 6-semialdehyde Formula: C6H11NO3 Charge: 0 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	R02D3.1	Lysine degradation
RM03102Name: L-2-Aminoadipate-6-semialdehyde:NAD+ 6-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R03102 click to see details on this item	1.2.1.31Name: L-aminoadipate-semialdehyde dehydrogenase Other names: aminoadipate semialdehyde dehydrogenase, 2-aminoadipate semialdehyde dehydrogenase, alpha-aminoadipate-semialdehyde dehydrogenase, alpha-aminoadipate reductase, 2-aminoadipic semialdehyde dehydrogenase, L-alpha-aminoadipate delta-semialdehyde oxidoreductase, L-alpha-aminoadipate delta-semialdehyde:NAD+ oxidoreductase, L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase, L-2-aminoadipate 6-semialdehyde:NAD(P)+ 6-oxidoreductase click to see details on this item	[m] : L2aadp6saName: L-2-Aminoadipate 6-semialdehyde Formula: C6H11NO3 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		L2aadpName: L-2-Aminoadipate Formula: C6H10NO4 Charge: -1 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	alh-9	Lysine degradation
RM03103Name: L-2-Aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R03103 click to see details on this item	1.2.1.31Name: L-aminoadipate-semialdehyde dehydrogenase Other names: aminoadipate semialdehyde dehydrogenase, 2-aminoadipate semialdehyde dehydrogenase, alpha-aminoadipate-semialdehyde dehydrogenase, alpha-aminoadipate reductase, 2-aminoadipic semialdehyde dehydrogenase, L-alpha-aminoadipate delta-semialdehyde oxidoreductase, L-alpha-aminoadipate delta-semialdehyde:NAD+ oxidoreductase, L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase, L-2-aminoadipate 6-semialdehyde:NAD(P)+ 6-oxidoreductase click to see details on this item	[m] : L2aadp6saName: L-2-Aminoadipate 6-semialdehyde Formula: C6H11NO3 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item		L2aadpName: L-2-Aminoadipate Formula: C6H10NO4 Charge: -1 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item	alh-9	Lysine degradation

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