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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 1.8.1.9
Name ..................................................... : Thioredoxin-disulfide reductase, etc.NADP-thioredoxin reductase, NADPH-thioredoxin reductase, Thioredoxin reductase (NADPH), NADPH2:oxidized thioredoxin oxidoreductase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K00384E1.8.1.9 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
Genes ..................................................... : trxr-1
Localization ..................................................... : Mitochondria, Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC02016Name: NADPH:oxidized-thioredoxin oxidoreductase
Type: Regular
Location: Cytosol
KEGG ID: R02016

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1.8.1.9Name: thioredoxin-disulfide reductase
Other names: NADP-thioredoxin reductase, NADPH-thioredoxin reductase, thioredoxin reductase (NADPH), NADPH2:oxidized thioredoxin oxidoreductase

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[c] : hName: H+
Formula: H
Charge: 1




click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item + trdoxName: Oxidized thioredoxin
Formula: X
Charge: 0




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nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item + trdrdName: Reduced thioredoxin
Formula: XH2
Charge: 0




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trxr-1
Reactive oxygen species metabolism
RM02016Name: NADPH:oxidized-thioredoxin oxidoreductase
Type: Regular
Location: Mitochondria
KEGG ID: R02016

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1.8.1.9Name: thioredoxin-disulfide reductase
Other names: NADP-thioredoxin reductase, NADPH-thioredoxin reductase, thioredoxin reductase (NADPH), NADPH2:oxidized thioredoxin oxidoreductase

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[m] : hName: H+
Formula: H
Charge: 1




click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item + trdoxName: Oxidized thioredoxin
Formula: X
Charge: 0




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nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item + trdrdName: Reduced thioredoxin
Formula: XH2
Charge: 0




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trxr-1
Reactive oxygen species metabolism
RC03596Name: Hydrogen selenide:NADP+ oxidoreductase
Type: Regular
Location: Cytosol
KEGG ID: R03596

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1.8.1.9Name: thioredoxin-disulfide reductase
Other names: NADP-thioredoxin reductase, NADPH-thioredoxin reductase, thioredoxin reductase (NADPH), NADPH2:oxidized thioredoxin oxidoreductase

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[c] : selnName: Selenide
Formula: HSe
Charge: -1




click to see details on this item + (3) nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item + (3) h2oName: H2O
Formula: H2O
Charge: 0




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selntName: Selenite
Formula: O3Se
Charge: -2




click to see details on this item + (3) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item + (4) hName: H+
Formula: H
Charge: 1




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trxr-1
Selenocompound metabolism
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