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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 1.3.1.3
Name ..................................................... : Delta4-3-oxosteroid 5beta-reductase, etc.3-oxo-Delta4-steroid 5beta-reductase, 5beta-reductase, Androstenedione 5beta-reductase, Cholestenone 5beta-reductase, Cortisone 5beta-reductase, Cortisone beta-reductase, Cortisone Delta4-5beta-reductase, Steroid 5beta-reductase, Testosterone 5beta-reductase, Delta4-3-ketosteroid 5beta-reductase, Delta4-5beta-reductase, Delta4-hydrogenase, 4,5beta-dihydrocortisone:NADP+ Delta4-oxidoreductase, 3-oxo-5beta-steroid:NADP+ Delta4-oxidoreductase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K00251AKR1D1; 3-oxo-5-beta-steroid 4-dehydrogenase [EC:1.3.1.3]
Genes ..................................................... : C07D8.6, F53F1.2, F53F1.3, T08H10.1, Y39G8B.1, Y39G8B.2, ZC443.1
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC04823Name: 3-oxo-Delta4-steroid 5beta-reductase
Type: Regular
Location: Cytosol
KEGG ID: R04823

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1.3.1.3Name: Delta4-3-oxosteroid 5beta-reductase
Other names: 3-oxo-Delta4-steroid 5beta-reductase, 5beta-reductase, androstenedione 5beta-reductase, cholestenone 5beta-reductase, cortisone 5beta-reductase, cortisone beta-reductase, cortisone Delta4-5beta-reductase, steroid 5beta-reductase, testosterone 5beta-reductase, Delta4-3-ketosteroid 5beta-reductase, Delta4-5beta-reductase, Delta4-hydrogenase, 4,5beta-dihydrocortisone:NADP+ Delta4-oxidoreductase, 3-oxo-5beta-steroid:NADP+ Delta4-oxidoreductase

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[c] : hName: H+
Formula: H
Charge: 1




click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item + xoldioloneName: "7alpha,12alpha-Dihydroxycholest-4-en-3-one"
Formula: C27H44O3
Charge: 0




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nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item + xoldiolonehName: "7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one"
Formula: C27H46O3
Charge: 0




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Y39G8B.1 | T08H10.1 | C07D8.6 | ZC443.1 | Y39G8B.2 | F53F1.3 | F53F1.2
Biosynthesis of bile acid-like molecules
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