WormFlux: mechanistic analysis of C. elegans metabolism

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? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	kynate
Name .....................................................	:	4-Hydroxy-2-quinolinecarboxylic acid, etc.Kynurenic acid, Kynurenate
Model ID .....................................................	:	C01717
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C01717
Formula .....................................................	:	C10H6NO3
Charge .....................................................	:	-1
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	kynate
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Not yet represented in WormPaths maps.

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC03445Name: 4-(2-Aminophenyl)-2,4-dioxobutanoate dehydratase Type: Regular Location: Cytosol KEGG ID: R03445 click to see details on this item	spontaneous	[c] : 4aphdobName: "4-(2-Aminophenyl)-2,4-dioxobutanoate" Formula: C10H8NO4 Charge: -1 click to see details on this item		h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + kynateName: 4-Hydroxy-2-quinolinecarboxylic acid Formula: C10H6NO3 Charge: -1 click to see details on this item	Not applicable	Miscellaneous
DMN0041Name: kynurenate demand Type: Demand Location: Cytosol KEGG ID: NA click to see details on this item	Not applicable	kynateName: 4-Hydroxy-2-quinolinecarboxylic acid Formula: C10H6NO3 Charge: -1 click to see details on this item[c]			Not applicable	Demand reactions
TCE5330Name: 4-Hydroxy-2-quinolinecarboxylic acid transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	kynateName: 4-Hydroxy-2-quinolinecarboxylic acid Formula: C10H6NO3 Charge: -1 click to see details on this item[e]		kynateName: 4-Hydroxy-2-quinolinecarboxylic acid Formula: C10H6NO3 Charge: -1 click to see details on this item[c]	Not determined	Transport
EX01717Name: 4-Hydroxy-2-quinolinecarboxylic acid exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	kynateName: 4-Hydroxy-2-quinolinecarboxylic acid Formula: C10H6NO3 Charge: -1 click to see details on this item[e]			Not applicable	Exchange with the environment

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