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  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal
Metabolite Overview
Abbreviation ..................................................... : dhbpt
Name ..................................................... : "6,7-Dihydrobiopterin", etc.Dihydrobiopterin, 6,7-Dihydrobiopterin, Quinoid-dihydrobiopterin, (6R)-6-(L-erythro-1,2-Dihydroxypropyl)-7,8-dihydro-6H-pterin
Model ID ..................................................... : C00268
KEGG ID (?) Compounds in KEGG database that match this compound. ..................................................... : C00268
Formula ..................................................... : C9H13N5O3
Charge ..................................................... : 0
Localization ..................................................... : Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. ..................................................... : dhbpt
Other associations ..................................................... : See reaction table below (11 reactions in total)

In WormPaths (?) Pathway maps where this metabolite is represented are listed here.

Letters after map name indicate the compartments the metabolite is placed in the map:

(c) Cytosol
(m) Mitochondria
(e) Extracellular space ..................................................... 		:   Go to map
Comments
ERROR
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RCC0140Name: glyceryl-ether monoxygenase
Type: Regular
Location: Cytosol
KEGG ID: R04044

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1.14.16.5Name: alkylglycerol monooxygenase
Other names: glyceryl-ether monooxygenase, glyceryl-ether cleaving enzyme, glyceryl ether oxygenase, glyceryl etherase, O-alkylglycerol monooxygenase

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[c] : ak2lgcholName: 1-Alkyl-2-lyso-sn-glycero-3-phosphocholine
Formula: C8H19NO6PRC2H4
Charge: 0




click to see details on this item + thbptName: Tetrahydrobiopterin
Formula: C9H15N5O3
Charge: 0




click to see details on this item + o2Name: O2
Formula: O2
Charge: 0




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hak2lgcholName: 1-hydroxyalkyl-2-lyso-sn-glycero-3-phosphocholine
Formula: C8H19NO6PRC2H4O
Charge: 0




click to see details on this item + dhbptName: "6,7-Dihydrobiopterin"
Formula: C9H13N5O3
Charge: 0




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




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agmo-1
Ether lipid metabolism
RC01793Name: 5,6,7,8-tetrahydrobiopterin:NAD+ oxidoreductase
Type: Regular
Location: Cytosol
KEGG ID: R01793

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1.5.1.34Name: 6,7-dihydropteridine reductase
Other names: 6,7-dihydropteridine:NAD(P)H oxidoreductase, DHPR, NAD(P)H:6,7-dihydropteridine oxidoreductase, NADH-dihydropteridine reductase, NADPH-dihydropteridine reductase, NADPH-specific dihydropteridine reductase, dihydropteridine (reduced nicotinamide adenine dinucleotide) reductase, dihydropteridine reductase, dihydropteridine reductase (NADH), 5,6,7,8-tetrahydropteridine:NAD(P)H+ oxidoreductase

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[c] : dhbptName: "6,7-Dihydrobiopterin"
Formula: C9H13N5O3
Charge: 0




click to see details on this item + hName: H+
Formula: H
Charge: 1




click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced
Formula: C21H27N7O14P2
Charge: -2




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nadName: Nicotinamide adenine dinucleotide
Formula: C21H26N7O14P2
Charge: -1




click to see details on this item + thbptName: Tetrahydrobiopterin
Formula: C9H15N5O3
Charge: 0




click to see details on this item
qdpr-1
Folate biosynthesis
RC01794Name: 5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase
Type: Regular
Location: Cytosol
KEGG ID: R01794

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1.5.1.34Name: 6,7-dihydropteridine reductase
Other names: 6,7-dihydropteridine:NAD(P)H oxidoreductase, DHPR, NAD(P)H:6,7-dihydropteridine oxidoreductase, NADH-dihydropteridine reductase, NADPH-dihydropteridine reductase, NADPH-specific dihydropteridine reductase, dihydropteridine (reduced nicotinamide adenine dinucleotide) reductase, dihydropteridine reductase, dihydropteridine reductase (NADH), 5,6,7,8-tetrahydropteridine:NAD(P)H+ oxidoreductase

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[c] : dhbptName: "6,7-Dihydrobiopterin"
Formula: C9H13N5O3
Charge: 0




click to see details on this item + hName: H+
Formula: H
Charge: 1




click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




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nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item + thbptName: Tetrahydrobiopterin
Formula: C9H15N5O3
Charge: 0




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qdpr-1
Folate biosynthesis
RC01795Name: L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)
Type: Regular
Location: Cytosol
KEGG ID: R01795

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1.14.16.1Name: phenylalanine 4-monooxygenase
Other names: phenylalaninase, phenylalanine 4-hydroxylase, phenylalanine hydroxylase

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[c] : o2Name: O2
Formula: O2
Charge: 0




click to see details on this item + phe-LName: L-Phenylalanine
Formula: C9H11NO2
Charge: 0




click to see details on this item + thbptName: Tetrahydrobiopterin
Formula: C9H15N5O3
Charge: 0




click to see details on this item
dhbptName: "6,7-Dihydrobiopterin"
Formula: C9H13N5O3
Charge: 0




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + tyr-LName: L-Tyrosine
Formula: C9H11NO3
Charge: 0




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pah-1
Folate biosynthesis
RC04734Name: 4a-hydroxytetrahydrobiopterin hydro-lyase
Type: Regular
Location: Cytosol
KEGG ID: R04734

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4.2.1.96Name: 4a-hydroxytetrahydrobiopterin dehydratase
Other names: 4alpha-hydroxy-tetrahydropterin dehydratase, pterin-4alpha-carbinolamine dehydratase, 4a-hydroxytetrahydrobiopterin hydro-lyase

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[c] : thbpt4acamName: Tetrahydrobiopterin-4a-carbinolamine
Formula: C9H15N5O4
Charge: 0




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dhbptName: "6,7-Dihydrobiopterin"
Formula: C9H13N5O3
Charge: 0




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




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pcbd-1
Folate biosynthesis
RC01816Name: anthranilate 3-monooxygenase
Type: Regular
Location: Cytosol
KEGG ID: R01816

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1.14.16.3Name: anthranilate 3-monooxygenase
Other names: anthranilate 3-hydroxylase, anthranilate hydroxylase, anthranilic hydroxylase, anthranilic acid hydroxylase

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[c] : thbptName: Tetrahydrobiopterin
Formula: C9H15N5O3
Charge: 0




click to see details on this item + anthName: Anthranilate
Formula: C7H6NO2
Charge: -1




click to see details on this item + o2Name: O2
Formula: O2
Charge: 0




click to see details on this item + hName: H+
Formula: H
Charge: 1




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3hanthrnName: 3-Hydroxyanthranilate
Formula: C7H7NO3
Charge: 0




click to see details on this item + dhbptName: "6,7-Dihydrobiopterin"
Formula: C9H13N5O3
Charge: 0




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




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Unknown
Tryptophan degradation
RC01814Name: L-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating) (Dihydrobiopterin forming)
Type: Regular
Location: Cytosol
KEGG ID: R01814

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1.14.16.4Name: tryptophan 5-monooxygenase
Other names: L-tryptophan hydroxylase, indoleacetic acid-5-hydroxylase, tryptophan 5-hydroxylase, tryptophan hydroxylase

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[c] : thbptName: Tetrahydrobiopterin
Formula: C9H15N5O3
Charge: 0




click to see details on this item + trp-LName: L-Tryptophan
Formula: C11H12N2O2
Charge: 0




click to see details on this item + o2Name: O2
Formula: O2
Charge: 0




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5htrpName: 5-Hydroxy-L-tryptophan
Formula: C11H12N2O3
Charge: 0




click to see details on this item + dhbptName: "6,7-Dihydrobiopterin"
Formula: C9H13N5O3
Charge: 0




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




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tph-1
Folate biosynthesis
RC01815Name: L-Tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating) (Dihydrobiopterin forming)
Type: Regular
Location: Cytosol
KEGG ID: R01815

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1.14.16.2Name: tyrosine 3-monooxygenase
Other names: L-tyrosine hydroxylase, tyrosine 3-hydroxylase, tyrosine hydroxylase

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[c] : thbptName: Tetrahydrobiopterin
Formula: C9H15N5O3
Charge: 0




click to see details on this item + tyr-LName: L-Tyrosine
Formula: C9H11NO3
Charge: 0




click to see details on this item + o2Name: O2
Formula: O2
Charge: 0




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34dhpheName: "3,4-Dihydroxy-L-phenylalanine"
Formula: C9H11NO4
Charge: 0




click to see details on this item + dhbptName: "6,7-Dihydrobiopterin"
Formula: C9H13N5O3
Charge: 0




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




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cat-2
Folate biosynthesis
DMN0048Name: dihydrobiopterin demand
Type: Demand
Location: Cytosol
KEGG ID: NA

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Not applicable
dhbptName: "6,7-Dihydrobiopterin"
Formula: C9H13N5O3
Charge: 0




click to see details on this item[c]
Not applicable
Demand reactions
TCE5325Name: 6,7-Dihydrobiopterin transport
Type: Transport
Location: Extracellular, Cytosol
KEGG ID: NA

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Not applicable
dhbptName: "6,7-Dihydrobiopterin"
Formula: C9H13N5O3
Charge: 0




click to see details on this item[c]
dhbptName: "6,7-Dihydrobiopterin"
Formula: C9H13N5O3
Charge: 0




click to see details on this item[e]
Not determined
Transport
EX00268Name: "6,7-Dihydrobiopterin" exchange
Type: Exchange
Location: Extracellular
KEGG ID: NA

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Not applicable
dhbptName: "6,7-Dihydrobiopterin"
Formula: C9H13N5O3
Charge: 0




click to see details on this item[e]
Not applicable
Exchange with the environment
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