Network Biomass WormPaths

FBAFlux Balance Analysis PEA

WormClustClustering- and enrichment-based association of genes with the metabolic network

Walhout Lab web page:
walhoutlab.umassmed.edu

Email for PEA:
lutfu.yilmaz@umassmed.edu

Statistical enrichment analysis of a given set of genes in our annotation categories (Walker et al., 2021). These categories are defined at four levels of increasing resolution (click to download in TSV format). For example, hphd-1 gene is in the category of lipids at Level 1, short-chain fatty acid degradation at Level 2, propionate degradation at Level 3, and propionate shunt pathway at Level 4. These categories cover the pathway maps in WormPaths.

• Enter the WormBase IDs of the genes of interest as comma delimited or in different lines in the box below and submit.
• See your results in an interactive table which illustrates the significance of enrichment or depletion at every category.
• Download your results as a tab-separated text file.

Note: When calculating enrichment p-values (hypergeometric), this tool assumes that all categorized genes in the iCEL model are detectable. For a list of genes in CSV format, click here. For the distribution of genes to the categories at the four levels in MS Excel, click here.

Change filename (optional) and download results as tab-separated text.

File name

PEA_StatsTable.txt

DOWNLOAD

Input

Enter WormBase IDs (e.g., WBGene00007974) Use comma between entries or enter each gene on a different line.

SUBMIT