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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 4.6.1.2
Name ..................................................... : Guanylate cyclase, etc.Guanylyl cyclase, Guanyl cyclase, GTP diphosphate-lyase (cyclizing)
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K01769E4.6.1.2; guanylate cyclase other [EC:4.6.1.2], K12323ANPRA NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2], K12319GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
Genes ..................................................... : gcy-1, gcy-12, gcy-14, gcy-15, gcy-17, gcy-18, gcy-2, gcy-20, gcy-21, gcy-23, gcy-28, gcy-3, gcy-31, gcy-33, gcy-34, gcy-35, gcy-36, gcy-37, gcy-5, gcy-8
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC00434Name: GTP diphosphate-lyase (cyclizing, 3',5'-cyclic-GMP-forming)
Type: Regular
Location: Cytosol
KEGG ID: R00434

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4.6.1.1Name: adenylate cyclase
Other names: adenylylcyclase, adenyl cyclase, 3',5'-cyclic AMP synthetase, ATP diphosphate-lyase (cyclizing)

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4.6.1.2Name: guanylate cyclase
Other names: guanylyl cyclase, guanyl cyclase, GTP diphosphate-lyase (cyclizing)

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[c] : gtpName: GTP
Formula: C10H12N5O14P3
Charge: -4




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35cgmpName: "3',5'-Cyclic GMP"
Formula: C10H11N5O7P
Charge: -1




click to see details on this item + ppiName: Diphosphate
Formula: HO7P2
Charge: -3




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[(gcy-1 | gcy-12 | gcy-14 | gcy-15 | gcy-18 | gcy-2 | gcy-20 | gcy-21 | gcy-23 | gcy-3 | gcy-34 | gcy-5 | gcy-8) | (gcy-17 | gcy-28) | (gcy-31 | gcy-33 | gcy-35 | gcy-36 | gcy-37)] | (acy-1 | acy-4) | acy-2 | (daf-11 | gcy-19 | gcy-22 | gcy-25 | gcy-29 | gcy-32 | gcy-4 | gcy-9)
Miscellaneous
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