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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 1.2.1.27
Name ..................................................... : Methylmalonate-semialdehyde dehydrogenase (acylating), etc.MSDH, MMSA dehydrogenase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K00140mmsA iolA ALDH6A1; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
Genes ..................................................... : alh-8
Localization ..................................................... : Mitochondria
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RM00705Name: 3-Oxopropanoate:NAD+ oxidoreductase (decarboxylating, CoA-acetylating)
Type: Regular
Location: Mitochondria
KEGG ID: R00705

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1.2.1.18Name: malonate-semialdehyde dehydrogenase (acetylating)
Other names: malonic semialdehyde oxidative decarboxylase

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1.2.1.27Name: methylmalonate-semialdehyde dehydrogenase (acylating)
Other names: MSDH, MMSA dehydrogenase

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[m] : coaName: Coenzyme A
Formula: C21H32N7O16P3S
Charge: -4




click to see details on this item + msaName: Malonate semialdehyde
Formula: C3H3O3
Charge: -1




click to see details on this item + nadName: Nicotinamide adenine dinucleotide
Formula: C21H26N7O14P2
Charge: -1




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accoaName: Acetyl-CoA
Formula: C23H34N7O17P3S
Charge: -4




click to see details on this item + co2Name: CO2
Formula: CO2
Charge: 0




click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced
Formula: C21H27N7O14P2
Charge: -2




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alh-8
Propionate degradation
RM00935Name: (S)-Methylmalonate semialdehyde:NAD+ oxidoreductase (CoA-propanoylating)
Type: Regular
Location: Mitochondria
KEGG ID: R00935

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1.2.1.27Name: methylmalonate-semialdehyde dehydrogenase (acylating)
Other names: MSDH, MMSA dehydrogenase

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[m] : 2mopName: 2-Methyl-3-oxopropanoate
Formula: C4H5O3
Charge: -1




click to see details on this item + coaName: Coenzyme A
Formula: C21H32N7O16P3S
Charge: -4




click to see details on this item + nadName: Nicotinamide adenine dinucleotide
Formula: C21H26N7O14P2
Charge: -1




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co2Name: CO2
Formula: CO2
Charge: 0




click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced
Formula: C21H27N7O14P2
Charge: -2




click to see details on this item + ppcoaName: Propanoyl-CoA
Formula: C24H36N7O17P3S
Charge: -4




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alh-8
Propionate degradation
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