WormFlux: mechanistic analysis of C. elegans metabolism

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Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	mhista
Name .....................................................	:	N-Methylhistamine, etc.1-Methylhistamine, 1-Methyl-4-(2-aminoethyl)imidazole, Ntau-Methylhistamine
Model ID .....................................................	:	C05127
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C05127
Formula .....................................................	:	C6H12N3
Charge .....................................................	:	+1
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	mhista
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Histidine degradation (c,e)

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC04674Name: N-Methylhistamine:oxygen oxidoreductase (deaminating) (copper-containing) Type: Regular Location: Cytosol KEGG ID: R04674 click to see details on this item	1.4.3.4Name: monoamine oxidase Other names: adrenalin oxidase, adrenaline oxidase, amine oxidase (ambiguous), amine oxidase (flavin-containing), amine:oxygen oxidoreductase (deaminating) (flavin-containing), epinephrine oxidase, MAO, MAO A, MAO B, MAO-A, MAO-B, monoamine oxidase A, monoamine oxidase B, monoamine:O2 oxidoreductase (deaminating), polyamine oxidase (ambiguous), serotonin deaminase, spermidine oxidase (ambiguous), spermine oxidase (ambiguous), tyraminase, tyramine oxidase click to see details on this item	[c] : mhistaName: N-Methylhistamine Formula: C6H12N3 Charge: 1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		3mldzName: 3-Methylimidazole acetaldehyde Formula: C6H8N2O Charge: 0 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item + h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item	amx-2	Histidine degradation
TCE7666Name: Methylhistamine transport Type: Transport Location: Extracellular, Cytosol KEGG ID: NA click to see details on this item	Not applicable	mhistaName: N-Methylhistamine Formula: C6H12N3 Charge: 1 click to see details on this item[c]		mhistaName: N-Methylhistamine Formula: C6H12N3 Charge: 1 click to see details on this item[e]	Not determined	Transport
EX05127Name: N-Methylhistamine exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	mhistaName: N-Methylhistamine Formula: C6H12N3 Charge: 1 click to see details on this item[e]			Not applicable	Exchange with the environment

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