WormFlux: mechanistic analysis of C. elegans metabolism

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? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

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PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	pan4p
Name .....................................................	:	Pantetheine 4'-phosphate, etc.4'-Phosphopantetheine, Phosphopantetheine, D-Pantetheine 4'-phosphate
Model ID .....................................................	:	C01134
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C01134
Formula .....................................................	:	C11H21N2O7PS
Charge .....................................................	:	-2
Localization .....................................................	:	Mitochondria, Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	pan4p
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Pantothenate and CoA biosynthesis (c,m)

iCEL1314

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Enzyme

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Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC03269Name: N-[(R)-4-Phosphopantothenoyl]-L-cysteine carboxy-lyase Type: Regular Location: Cytosol KEGG ID: R03269 click to see details on this item	4.1.1.36Name: phosphopantothenoylcysteine decarboxylase Other names: 4-phosphopantotheoylcysteine decarboxylase, 4-phosphopantothenoyl-L-cysteine decarboxylase, PPC-decarboxylase, N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase click to see details on this item	[c] : 4ppcysName: N-((R)-4-Phosphopantothenoyl)-L-cysteine Formula: C12H20N2O9PS Charge: -3 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + pan4pName: Pantetheine 4'-phosphate Formula: C11H21N2O7PS Charge: -2 click to see details on this item	F25H9.6	Pantothenate and CoA biosynthesis
RM03035Name: ATP:pantetheine-4-phosphate adenylyltransferase Type: Regular Location: Mitochondria KEGG ID: R03035 click to see details on this item	2.7.7.3Name: pantetheine-phosphate adenylyltransferase Other names: dephospho-CoA pyrophosphorylase, pantetheine phosphate adenylyltransferase, dephospho-coenzyme A pyrophosphorylase, 3'-dephospho-CoA pyrophosphorylase click to see details on this item	[m] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + pan4pName: Pantetheine 4'-phosphate Formula: C11H21N2O7PS Charge: -2 click to see details on this item		dpcoaName: Dephospho-CoA Formula: C21H33N7O13P2S Charge: -2 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	Y65B4A.8	Pantothenate and CoA biosynthesis
TCM1039Name: Pantetheine 4'-phosphate transport Type: Transport Location: Mitochondria, Cytosol KEGG ID: NA click to see details on this item	Not applicable	pan4pName: Pantetheine 4'-phosphate Formula: C11H21N2O7PS Charge: -2 click to see details on this item[c]		pan4pName: Pantetheine 4'-phosphate Formula: C11H21N2O7PS Charge: -2 click to see details on this item[m]	Not determined	Transport

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