WormFlux: mechanistic analysis of C. elegans metabolism

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? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

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PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	Sfglutth
Name .....................................................	:	S-Formylglutathione
Model ID .....................................................	:	C01031
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C01031
Formula .....................................................	:	C11H16N3O7S
Charge .....................................................	:	-1
Localization .....................................................	:	Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	Sfglutth
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Not yet represented in WormPaths maps.

iCEL1314

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ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC06983Name: S-(hydroxymethyl)glutathione dehydrogenase Type: Regular Location: Cytosol KEGG ID: R06983 click to see details on this item	1.1.1.284Name: S-(hydroxymethyl)glutathione dehydrogenase Other names: NAD-linked formaldehyde dehydrogenase (incorrect), formaldehyde dehydrogenase (incorrect), formic dehydrogenase (incorrect), class III alcohol dehydrogenase, ADH3, chi-ADH, FDH (incorrect), formaldehyde dehydrogenase (glutathione) (incorrect), GS-FDH (incorrect), glutathione-dependent formaldehyde dehydrogenase (incorrect), NAD-dependent formaldehyde dehydrogenase, GD-FALDH, NAD- and glutathione-dependent formaldehyde dehydrogenase click to see details on this item	[c] : hmgthName: hydroxymethylglutathione Formula: C11H18N3O7S Charge: -1 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		SfglutthName: S-Formylglutathione Formula: C11H16N3O7S Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	H24K24.3	Miscellaneous
RC00527Name: S-Formylglutathione hydrolase Type: Regular Location: Cytosol KEGG ID: R00527 click to see details on this item	3.1.2.12Name: S-formylglutathione hydrolase click to see details on this item	[c] : SfglutthName: S-Formylglutathione Formula: C11H16N3O7S Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		forName: Formate Formula: CH1O2 Charge: -1 click to see details on this item + gthrdName: Reduced glutathione Formula: C10H16N3O6S Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	Y48G10A.1	Miscellaneous
RC07140Name: S-(hydroxymethyl)glutathione:NADP+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R07140 click to see details on this item	1.1.1.284Name: S-(hydroxymethyl)glutathione dehydrogenase Other names: NAD-linked formaldehyde dehydrogenase (incorrect), formaldehyde dehydrogenase (incorrect), formic dehydrogenase (incorrect), class III alcohol dehydrogenase, ADH3, chi-ADH, FDH (incorrect), formaldehyde dehydrogenase (glutathione) (incorrect), GS-FDH (incorrect), glutathione-dependent formaldehyde dehydrogenase (incorrect), NAD-dependent formaldehyde dehydrogenase, GD-FALDH, NAD- and glutathione-dependent formaldehyde dehydrogenase click to see details on this item	[c] : hmgthName: hydroxymethylglutathione Formula: C11H18N3O7S Charge: -1 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item		SfglutthName: S-Formylglutathione Formula: C11H16N3O7S Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item	H24K24.3	Miscellaneous

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