Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	prostgh2
Name .....................................................	:	Prostaglandin H2, etc.(5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate, (5Z,13E,15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate, PGH2, (5Z,9alpha,11alpha,13E,15S)-9,11-Epidioxy-15-hydroxy-prosta-5,13-dienoate
Model ID .....................................................	:	C00427
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00427
Formula .....................................................	:	C20H31O5
Charge .....................................................	:	-1
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	prostgh2
Other associations .....................................................	:	See reaction table below.
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Not yet represented in WormPaths maps.

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RCC0078Name: Prostaglandin G/H synthase Type: Regular Location: Cytosol KEGG ID: R01590;R00073 click to see details on this item	1.14.99.1Name: prostaglandin-endoperoxide synthase Other names: prostaglandin synthase, prostaglandin G/H synthase, (PG)H synthase, PG synthetase, prostaglandin synthetase, fatty acid cyclooxygenase, prostaglandin endoperoxide synthetase click to see details on this item	[c] : arachdName: arachidonic acid Formula: C20H31O2 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + (2) o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + prostgh2Name: Prostaglandin H2 Formula: C20H31O5 Charge: -1 click to see details on this item	To be determined	Arachidonic acid metabolism
RC02265Name: (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13- dienoate E-isomerase Type: Regular Location: Cytosol KEGG ID: R02265 click to see details on this item	5.3.99.3Name: prostaglandin-E synthase Other names: prostaglandin-H2 E-isomerase, endoperoxide isomerase, endoperoxide isomerase, prostaglandin R-prostaglandin E isomerase, prostaglandin endoperoxide E isomerase, PGE isomerase, PGH-PGE isomerase, PGE2 isomerase, prostaglandin endoperoxide E2 isomerase, prostaglandin H-E isomerase click to see details on this item	[c] : prostgh2Name: Prostaglandin H2 Formula: C20H31O5 Charge: -1 click to see details on this item		prostge2Name: Prostaglandin E2 Formula: C20H31O5 Charge: -1 click to see details on this item	pges-2 | ZC395.10	Arachidonic acid metabolism
RC02266Name: Prostaglandin-H2 D-isomerase (Precursor) Type: Regular Location: Cytosol KEGG ID: R02266 click to see details on this item	5.3.99.2Name: prostaglandin-D synthase Other names: prostaglandin-H2 Delta-isomerase, prostaglandin-R-prostaglandin D isomerase, PGH-PGD isomerase(5,13)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate Delta-isomerase (incorrect), (5,13)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase, prostaglandin endoperoxide Delta-isomerase, prostaglandin D synthetase click to see details on this item	[c] : prostgh2Name: Prostaglandin H2 Formula: C20H31O5 Charge: -1 click to see details on this item		prostgd2Name: Prostaglandin D2 Formula: C20H31O5 Charge: -1 click to see details on this item	gst-11	Arachidonic acid metabolism
TCE5389Name: Prostaglandin H2 transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	prostgh2Name: Prostaglandin H2 Formula: C20H31O5 Charge: -1 click to see details on this item[e]		prostgh2Name: Prostaglandin H2 Formula: C20H31O5 Charge: -1 click to see details on this item[c]	Not determined	Transport
EX00427Name: Prostaglandin H2 exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	prostgh2Name: Prostaglandin H2 Formula: C20H31O5 Charge: -1 click to see details on this item[e]			Not applicable	Exchange with the environment

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