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Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
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PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal
Metabolite Overview
Abbreviation ..................................................... : nac
Name ..................................................... : Nicotinate, etc.Nicotinic acid, Niacin, 3-Pyridinecarboxylic acid
Model ID ..................................................... : C00253
KEGG ID (?) Compounds in KEGG database that match this compound. ..................................................... : C00253
Formula ..................................................... : C6H4NO2
Charge ..................................................... : -1
Localization ..................................................... : Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. ..................................................... : nac
Other associations ..................................................... : See reaction table below (6 reactions in total)

In WormPaths (?) Pathway maps where this metabolite is represented are listed here.

Letters after map name indicate the compartments the metabolite is placed in the map:

(c) Cytosol
(m) Mitochondria
(e) Extracellular space ..................................................... 		: Nicotinate and nicotinamide metabolism (c)
Comments
ERROR
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC02295Name: Nicotinate D-ribonucleoside:orthophosphate ribosyltransferase
Type: Regular
Location: Cytosol
KEGG ID: R02295

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2.4.2.1Name: purine-nucleoside phosphorylase
Other names: inosine phosphorylase, PNPase, PUNPI, PUNPII, inosine-guanosine phosphorylase, nucleotide phosphatase, purine deoxynucleoside phosphorylase, purine deoxyribonucleoside phosphorylase, purine nucleoside phosphorylase, purine ribonucleoside phosphorylase

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[c] : hName: H+
Formula: H
Charge: 1




click to see details on this item + nacName: Nicotinate
Formula: C6H4NO2
Charge: -1




click to see details on this item + r1pName: alpha-D-Ribose 1-phosphate
Formula: C5H9O8P
Charge: -2




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nicrnsName: Nicotinate D-ribonucleoside
Formula: C11H13NO6
Charge: 0




click to see details on this item + piName: Phosphate
Formula: HO4P
Charge: -2




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K02D7.1
Nicotinate and nicotinamide metabolism
RC01724Name: Nicotinate D-ribonucleotide:diphosphate phosphoribosyltransferase
Type: Regular
Location: Cytosol
KEGG ID: R01724

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6.3.4.21Name: nicotinate phosphoribosyltransferase
Other names: niacin ribonucleotidase, nicotinic acid mononucleotide glycohydrolase, nicotinic acid mononucleotide pyrophosphorylase, nicotinic acid phosphoribosyltransferase, nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase

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[c] : hName: H+
Formula: H
Charge: 1




click to see details on this item + nacName: Nicotinate
Formula: C6H4NO2
Charge: -1




click to see details on this item + prppName: 5-Phospho-alpha-D-ribose 1-diphosphate
Formula: C5H8O14P3
Charge: -5




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nicrntName: Nicotinate D-ribonucleotide
Formula: C11H12NO9P
Charge: -2




click to see details on this item + ppiName: Diphosphate
Formula: HO7P2
Charge: -3




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nprt-1
Nicotinate and nicotinamide metabolism
RC01268Name: nicotinamidase
Type: Regular
Location: Cytosol
KEGG ID: R01268

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3.5.1.19Name: nicotinamidase
Other names: nicotinamide deaminase, nicotinamide amidase, YNDase

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[c] : h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + ncamName: Nicotinamide
Formula: C6H6N2O
Charge: 0




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nacName: Nicotinate
Formula: C6H4NO2
Charge: -1




click to see details on this item + nh4Name: Ammonium
Formula: H4N
Charge: 1




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pnc-1 | pnc-2
Nicotinate and nicotinamide metabolism
TCE5405Name: Nicotinic acid (niacin) transport
Type: Transport
Location: Cytosol, Extracellular
KEGG ID: NA

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Not applicable
na1Name: Sodium
Formula: Na
Charge: 1




click to see details on this item[e] + nacName: Nicotinate
Formula: C6H4NO2
Charge: -1




click to see details on this item[e]
na1Name: Sodium
Formula: Na
Charge: 1




click to see details on this item[c] + nacName: Nicotinate
Formula: C6H4NO2
Charge: -1




click to see details on this item[c]
Not determined
Transport
TCE0687Name: Nicotinate transport
Type: Transport
Location: Cytosol, Extracellular
KEGG ID: NA

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Not applicable
nacName: Nicotinate
Formula: C6H4NO2
Charge: -1




click to see details on this item[e]
nacName: Nicotinate
Formula: C6H4NO2
Charge: -1




click to see details on this item[c]
Not determined
Transport
EX00253Name: Nicotinate exchange
Type: Exchange
Location: Extracellular
KEGG ID: NA

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Not applicable
nacName: Nicotinate
Formula: C6H4NO2
Charge: -1




click to see details on this item[e]
Not applicable
Exchange with the environment
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