Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	Rtotal
Name .....................................................	:	R total, etc.Fatty acid
Model ID .....................................................	:	C00162
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00162
Formula .....................................................	:	CO2FULLR
Charge .....................................................	:	-1
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	Rtotal
Other associations .....................................................	:	See reaction table below (8 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Ether lipid metabolism (c), Glycerophospholipid metabolism (c), Sphingolipid metabolism (c)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC04311Name: 1-Acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase Type: Regular Location: Cytosol KEGG ID: R04311 click to see details on this item	2.5.1.26Name: alkylglycerone-phosphate synthase Other names: alkyldihydroxyacetonephosphate synthase, alkyldihydroxyacetone phosphate synthetase, alkyl DHAP synthetase, alkyl-DHAP, dihydroxyacetone-phosphate acyltransferase, DHAP-AT click to see details on this item	[c] : adhapName: 1-Acyl-glycerone 3-phosphate Formula: C4H4O7PR Charge: -2 click to see details on this item + alkylR1ohName: hydroxy alkyl chain Formula: C2H5OFULLR Charge: 0 click to see details on this item		RtotalName: R total Formula: CO2FULLR Charge: -1 click to see details on this item + akdhapName: Alkyl-glycerone 3-phosphate Formula: C3H4O6PRC2H4 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	ads-1	Ether lipid metabolism
RCC0128Name: fatty-acid--CoA ligase (Rtotal) Type: Regular Location: Cytosol KEGG ID: R00390 click to see details on this item	6.2.1.3Name: long-chain-fatty-acid---CoA ligase Other names: acyl-CoA synthetase, fatty acid thiokinase (long chain), acyl-activating enzyme, palmitoyl-CoA synthase, lignoceroyl-CoA synthase, arachidonyl-CoA synthetase, acyl coenzyme A synthetase, acyl-CoA ligase, palmitoyl coenzyme A synthetase, thiokinase, palmitoyl-CoA ligase, acyl-coenzyme A ligase, fatty acid CoA ligase, long-chain fatty acyl coenzyme A synthetase, oleoyl-CoA synthetase, stearoyl-CoA synthetase, long chain fatty acyl-CoA synthetase, long-chain acyl CoA synthetase, fatty acid elongase, LCFA synthetase, pristanoyl-CoA synthetase, ACS3, long-chain acyl-CoA synthetase I, long-chain acyl-CoA synthetase II, fatty acyl-coenzyme A synthetase, long-chain acyl-coenzyme A synthetase, FAA1 click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + RtotalName: R total Formula: CO2FULLR Charge: -1 click to see details on this item		ampName: AMP Formula: C10H12N5O7P Charge: -2 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item + RtotalcoaName: R total Coenzyme A Formula: CO2FULLRC21H31N7O15P3S Charge: -4 click to see details on this item	acs-2 | acs-3 | acs-4 | acs-5 | acs-13 | acs-15 | acs-17 | acs-18	Miscellaneous
RC02746Name: 1-Acyl-sn-glycero-3-phosphocholine acylhydrolase Type: Regular Location: Cytosol KEGG ID: R02746;R02747 click to see details on this item	3.1.1.5Name: lysophospholipase Other names: lecithinase B, lysolecithinase, phospholipase B, lysophosphatidase, lecitholipase, phosphatidase B, lysophosphatidylcholine hydrolase, lysophospholipase A1, lysophopholipase L2, lysophospholipase transacylase, neuropathy target esterase, NTE, NTE-LysoPLA, NTE-lysophospholipase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + lpcholName: Lysophosphatidylcholine Formula: C8H19NO5PFULLRCO2 Charge: 0 click to see details on this item		RtotalName: R total Formula: CO2FULLR Charge: -1 click to see details on this item + g3pcName: sn-Glycero-3-phosphocholine Formula: C8H20NO6P Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	ZK370.4 | C27A7.5 | M05B5.4 | ath-1	Glycerophospholipid metabolism
RC03416Name: 1-Acyl-sn-glycero-3-phosphoethanolamine aldehydohydrolase Type: Regular Location: Cytosol KEGG ID: R03416;R03417 click to see details on this item	3.1.1.5Name: lysophospholipase Other names: lecithinase B, lysolecithinase, phospholipase B, lysophosphatidase, lecitholipase, phosphatidase B, lysophosphatidylcholine hydrolase, lysophospholipase A1, lysophopholipase L2, lysophospholipase transacylase, neuropathy target esterase, NTE, NTE-LysoPLA, NTE-lysophospholipase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + acg3peName: 1-Acyl-sn-glycero-3-phosphoethanolamine;2-Acyl-sn-glycero-3-phosphoethanolamine Formula: C6H13NO7PR Charge: 0 click to see details on this item		RtotalName: R total Formula: CO2FULLR Charge: -1 click to see details on this item + g3peName: sn-Glycero-3-phosphoethanolamine Formula: C5H14NO6P Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	ZK370.4 | C27A7.5 | ath-1	Glycerophospholipid metabolism
RC06518Name: N-acylsphingosine amidohydrolase Type: Regular Location: Cytosol KEGG ID: R06518 click to see details on this item	3.5.1.23Name: ceramidase Other names: acylsphingosine deacylase, glycosphingolipid ceramide deacylase click to see details on this item	[c] : dhcrm_ceName: dihydroceramide Formula: C19H40NO2FULLRCO Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		RtotalName: R total Formula: CO2FULLR Charge: -1 click to see details on this item + sphgn_ceName: Sphinganine Formula: C19H42NO2 Charge: 1 click to see details on this item	W02F12.2	Sphingolipid metabolism
RC01494Name: N-Acylsphingosine amidohydrolase Type: Regular Location: Cytosol KEGG ID: R01494 click to see details on this item	3.5.1.23Name: ceramidase Other names: acylsphingosine deacylase, glycosphingolipid ceramide deacylase click to see details on this item	[c] : crm_ceName: ceramide Formula: C19H38NO2FULLRCO Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		RtotalName: R total Formula: CO2FULLR Charge: -1 click to see details on this item + sphings_ceName: Sphingosine Formula: C19H40NO2 Charge: 1 click to see details on this item	W02F12.2 | (asah-2 | asah-1)	Sphingolipid metabolism
TCE5396Name: R total transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	RtotalName: R total Formula: CO2FULLR Charge: -1 click to see details on this item[e]		RtotalName: R total Formula: CO2FULLR Charge: -1 click to see details on this item[c]	Not determined	Transport
EX00162Name: R total exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	RtotalName: R total Formula: CO2FULLR Charge: -1 click to see details on this item[e]			Not applicable	Exchange with the environment

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