WormFlux: mechanistic analysis of C. elegans metabolism

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? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	4hbz
Name .....................................................	:	4-Hydroxybenzoate, etc.Hydroxybenzoic acid, 4-Hydroxybenzoic acid, Hydroxybenzenecarboxylic acid
Model ID .....................................................	:	C00156
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00156
Formula .....................................................	:	C7H5O3
Charge .....................................................	:	-1
Localization .....................................................	:	Mitochondria, Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	4hbz
Other associations .....................................................	:	See reaction table below (6 reactions in total)

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Ubiquinone metabolism (c,e,m)

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM01301Name: 4-Hydroxybenzoyl-CoA hydrolase Type: Regular Location: Mitochondria KEGG ID: R01301 click to see details on this item	3.1.2.23Name: 4-hydroxybenzoyl-CoA thioesterase click to see details on this item	[m] : 4hbzcoaName: 4-hydroxybenoyl-CoA Formula: C28H36N7O18P3S Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		4hbzName: 4-Hydroxybenzoate Formula: C7H5O3 Charge: -1 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	Unknown	Ubiquinone metabolism
RM07273Name: nonaprenyl-4-hydroxybenzoate transferase Type: Regular Location: Mitochondria KEGG ID: R07273 click to see details on this item	2.5.1.39Name: 4-hydroxybenzoate polyprenyltransferase Other names: nonaprenyl-4-hydroxybenzoate transferase, 4-hydroxybenzoate transferase, p-hydroxybenzoate dimethylallyltransferase, p-hydroxybenzoate polyprenyltransferase, p-hydroxybenzoic acid-polyprenyl transferase, p-hydroxybenzoic-polyprenyl transferase, 4-hydroxybenzoate nonaprenyltransferase click to see details on this item	[m] : 4hbzName: 4-Hydroxybenzoate Formula: C7H5O3 Charge: -1 click to see details on this item + nonadpName: all-trans-Nonaprenyl diphosphate Formula: C45H73O7P2 Charge: -3 click to see details on this item		3nphbName: 3-Nonaprenyl-4-hydroxybenzoate Formula: C52H77O3 Charge: -1 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	coq-2	Ubiquinone metabolism
RC01301Name: 4-Hydroxybenzoyl-CoA hydrolase Type: Regular Location: Cytosol KEGG ID: R01301 click to see details on this item	3.1.2.23Name: 4-hydroxybenzoyl-CoA thioesterase click to see details on this item	[c] : 4hbzcoaName: 4-hydroxybenoyl-CoA Formula: C28H36N7O18P3S Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		4hbzName: 4-Hydroxybenzoate Formula: C7H5O3 Charge: -1 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	Unknown	Ubiquinone metabolism
TCE5096Name: 4-Hydroxybenzoate secretion Type: Transport Location: Extracellular, Cytosol KEGG ID: NA click to see details on this item	Not applicable	4hbzName: 4-Hydroxybenzoate Formula: C7H5O3 Charge: -1 click to see details on this item[c]		4hbzName: 4-Hydroxybenzoate Formula: C7H5O3 Charge: -1 click to see details on this item[e]	To be determined	Transport
TCM1033Name: 4-Hydroxybenzoate transport Type: Transport Location: Mitochondria, Cytosol KEGG ID: NA click to see details on this item	Not applicable	4hbzName: 4-Hydroxybenzoate Formula: C7H5O3 Charge: -1 click to see details on this item[c]		4hbzName: 4-Hydroxybenzoate Formula: C7H5O3 Charge: -1 click to see details on this item[m]	Not determined	Transport
EX00156Name: 4-Hydroxybenzoate exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	4hbzName: 4-Hydroxybenzoate Formula: C7H5O3 Charge: -1 click to see details on this item[e]			Not applicable	Exchange with the environment

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